Research · Evidence register · AMPK signalling
AMPK signalling: indexed research register 2020–2026
The Europe PMC index holds 16,858 records for ampk signalling published between 2020 and 2026, of which 5,943 are typed as reviews and 70 as randomised controlled trials. This register reports what the literature contains and how to reach it, never whether a practice works.
Four-eyes reviewed. Published from the governed article ledger. This register measures a literature index; it is not a treatment recommendation.
Article overview
A provenance-preserving register of the peer-reviewed literature Europe PMC indexes for ampk signalling, with publication types, journal spread and anchor records that any reader can resolve by DOI.
What this register counts
This page reports how much peer-reviewed literature is indexed on ampk signalling, not what that literature concludes. Every headline number comes from a live query against the whole Europe PMC index for the term “AMPK signaling”, restricted to a first publication date between 2020-01-01 and 2026-08-05, and each query is published as a link you can open and re-run. On 2026-08-05 the term resolved to 16,858 records. These are complete counts over the index, not estimates and not a sample. A catalogue count is still a measurement of a catalogue, and a catalogue is not the state of knowledge.
Publication types and access
Publication type comes from the index metadata rather than from any reading of the articles. Of the 16,858 records, the index types 5,943 as a review or meta-analysis and 70 as a randomised controlled trial. 14,338 records are flagged open access, which means their full text can be read without payment and a reader can check any statement against the source. Records may carry more than one type, and records with no type assigned are counted in the total but in neither category, so the categories do not sum to the total and were never intended to.
How the literature is distributed
Counts by publication year run 2020: 1,563, 2021: 2,207, 2022: 2,477, 2023: 2,246, 2024: 2,546, 2025: 3,657, 2026: 2,137, with 2025 the heaviest year in the window. Within the 233 records Metatron Health holds in its dated local snapshot of 2026-08-05, the literature spans 135 distinct journals, led by: International journal of molecular sciences (15 records), Frontiers in immunology (6 records), Frontiers in nutrition (6 records), Animals : an open access journal from MDPI (6 records), Cells (6 records). That journal breakdown describes the captured snapshot rather than the full index, and is offered as an orientation to where this field publishes, not as a complete ranking.
What this register does not establish
A record count is not evidence of benefit, and being indexed is not endorsement by anyone, including us. This page carries no effect estimate, no comparison between treatments, no dose and no recommendation. A large literature can be large because a question is hard, commercially interesting, or repeatedly studied at low quality, and a captured subset can over-represent whichever records the index returned first. Anyone using this register to decide what to take or which practitioner to see is using it for something it was not built to do.
Anchor records and how to verify them
Each register names anchor records that a reader can resolve independently: The Biochemical journal (2026); Molecular biology reports (2026); Molecular and cellular endocrinology (2026); Biochemical and biophysical research communications (2026). Anchors are selected deterministically, favouring reviews and trials, then open access, then citation count, with one record per journal. Records carrying a retraction or withdrawal notice in the index are excluded. Every anchor carries a DOI, its indexed grant support and its correction state as observed on 2026-08-05. Before this page was published, an independent review lane resolved every source URL listed below and recorded the hash of what it received.
Machine-readable reviewed statements
CLM-EVREG-AMPK-SIGNALING-001
The Europe PMC search index reports 16,858 records for the query “"AMPK signaling" AND FIRST_PDATE:[2020-01-01 TO 2026-08-05]”, resolved on 2026-08-05.
Evidence class: bibliographic index count
Sources: SRC-EPMC-INDEX-AMPK-SIGNALING
CLM-EVREG-AMPK-SIGNALING-002
Of those records, the index types 5,943 as a review or meta-analysis, resolved on 2026-08-05.
Evidence class: bibliographic index count
Sources: SRC-EPMC-REVIEWS-AMPK-SIGNALING
CLM-EVREG-AMPK-SIGNALING-003
The index types 70 of those records as a randomised controlled trial, resolved on 2026-08-05.
Evidence class: bibliographic index count
Sources: SRC-EPMC-TRIALS-AMPK-SIGNALING
CLM-EVREG-AMPK-SIGNALING-004
14,338 of those records are flagged open access, meaning their full text can be read without payment, resolved on 2026-08-05.
Evidence class: bibliographic index count
Sources: SRC-EPMC-OPENACCESS-AMPK-SIGNALING
CLM-EVREG-AMPK-SIGNALING-101
The Biochemical journal published the record titled “Illuminating compartmentalized AMPK signaling in single cells” in 2026 under DOI 10.1042/bcj20250267.
Evidence class: bibliographic record
Sources: SRC-EPMC-AMPK-SIGNALING-01
CLM-EVREG-AMPK-SIGNALING-102
Molecular biology reports published the record titled “Mechanisms and therapeutic potential of AMPK signaling pathway in the regulation of lipid metabolism” in 2026 under DOI 10.1007/s11033-026-12516-0.
Evidence class: bibliographic record
Sources: SRC-EPMC-AMPK-SIGNALING-02
CLM-EVREG-AMPK-SIGNALING-103
Molecular and cellular endocrinology published the record titled “Curcusone D improves metabolic dysfunction associated steatotic liver disease via activation of the AMPK signaling” in 2026 under DOI 10.1016/j.mce.2026.112847.
Evidence class: bibliographic record
Sources: SRC-EPMC-AMPK-SIGNALING-03
CLM-EVREG-AMPK-SIGNALING-104
Biochemical and biophysical research communications published the record titled “GPAT3 is associated with lipid deposition and AMPK signaling in skeletal muscle” in 2026 under DOI 10.1016/j.bbrc.2026.154172.
Evidence class: bibliographic record
Sources: SRC-EPMC-AMPK-SIGNALING-04
Sources and governing contracts
- SRC-EPMC-INDEX-AMPK-SIGNALING — Europe PMC, EMBL-EBI, Europe PMC search index, records of any type: "AMPK signaling" AND FIRST_PDATE:[2020-01-01 TO 2026-08-05]. Role: bibliographic index. Public literature index operated by EMBL-EBI. Metatron Health has no commercial or editorial relationship with the index operator and receives no payment connected to what it indexes. Open source
- SRC-EPMC-REVIEWS-AMPK-SIGNALING — Europe PMC, EMBL-EBI, Europe PMC search index, records typed as a review or meta-analysis: "AMPK signaling" AND FIRST_PDATE:[2020-01-01 TO 2026-08-05] AND PUB_TYPE:"Review". Role: bibliographic index. Public literature index operated by EMBL-EBI. Metatron Health has no commercial or editorial relationship with the index operator and receives no payment connected to what it indexes. Open source
- SRC-EPMC-TRIALS-AMPK-SIGNALING — Europe PMC, EMBL-EBI, Europe PMC search index, records typed as a randomised controlled trial: "AMPK signaling" AND FIRST_PDATE:[2020-01-01 TO 2026-08-05] AND PUB_TYPE:"Randomized Controlled Trial". Role: bibliographic index. Public literature index operated by EMBL-EBI. Metatron Health has no commercial or editorial relationship with the index operator and receives no payment connected to what it indexes. Open source
- SRC-EPMC-OPENACCESS-AMPK-SIGNALING — Europe PMC, EMBL-EBI, Europe PMC search index, records whose full text is free to read: "AMPK signaling" AND FIRST_PDATE:[2020-01-01 TO 2026-08-05] AND OPEN_ACCESS:y. Role: bibliographic index. Public literature index operated by EMBL-EBI. Metatron Health has no commercial or editorial relationship with the index operator and receives no payment connected to what it indexes. Open source
- SRC-EPMC-AMPK-SIGNALING-01 — The Biochemical journal, Illuminating compartmentalized AMPK signaling in single cells. Role: independent research. Independent peer-reviewed article. Metatron Health has no financial or editorial relationship with its authors, journal or funders and earns nothing from citing it. Open source
- SRC-EPMC-AMPK-SIGNALING-02 — Molecular biology reports, Mechanisms and therapeutic potential of AMPK signaling pathway in the regulation of lipid metabolism. Role: independent research. Independent peer-reviewed article. Metatron Health has no financial or editorial relationship with its authors, journal or funders and earns nothing from citing it. Open source
- SRC-EPMC-AMPK-SIGNALING-03 — Molecular and cellular endocrinology, Curcusone D improves metabolic dysfunction associated steatotic liver disease via activation of the AMPK signaling. Role: independent research. Independent peer-reviewed article. Metatron Health has no financial or editorial relationship with its authors, journal or funders and earns nothing from citing it. Open source
- SRC-EPMC-AMPK-SIGNALING-04 — Biochemical and biophysical research communications, GPAT3 is associated with lipid deposition and AMPK signaling in skeletal muscle. Role: independent research. Independent peer-reviewed article. Metatron Health has no financial or editorial relationship with its authors, journal or funders and earns nothing from citing it. Open source
Boundary
This page counts published research records. It does not provide diagnosis, prescribing, treatment selection or individualized medical advice, and a record count must never be read as evidence that a practice is effective or safe.