Research · Evidence register · Cellular senescence

Cellular senescence: indexed research register 2020–2026

The Europe PMC index holds 47,814 records for cellular senescence published between 2020 and 2026, of which 15,497 are typed as reviews and 144 as randomised controlled trials. This register reports what the literature contains and how to reach it, never whether a practice works.

Indexed records
47814
Reviews
15497
Trials
144
Open access
36775

Article overview

A provenance-preserving register of the peer-reviewed literature Europe PMC indexes for cellular senescence, with publication types, journal spread and anchor records that any reader can resolve by DOI.

What this register counts

This page reports how much peer-reviewed literature is indexed on cellular senescence, not what that literature concludes. Every headline number comes from a live query against the whole Europe PMC index for the term “cellular senescence”, restricted to a first publication date between 2020-01-01 and 2026-08-08, and each query is published as a link you can open and re-run. On 2026-08-08 the term resolved to 47,814 records. These are complete counts over the index, not estimates and not a sample. A catalogue count is still a measurement of a catalogue, and a catalogue is not the state of knowledge.

Publication types and access

Publication type comes from the index metadata rather than from any reading of the articles. Of the 47,814 records, the index types 15,497 as a review or meta-analysis and 144 as a randomised controlled trial. 36,775 records are flagged open access, which means their full text can be read without payment and a reader can check any statement against the source. Records may carry more than one type, and records with no type assigned are counted in the total but in neither category, so the categories do not sum to the total and were never intended to.

How the literature is distributed

Counts by publication year run 2020: 4,290, 2021: 5,645, 2022: 6,211, 2023: 6,564, 2024: 7,810, 2025: 10,709, 2026: 6,513, with 2025 the heaviest year in the window. Within the 429 records Metatron Health holds in its dated local snapshot of 2026-08-08, the literature spans 230 distinct journals, led by: Aging cell (19 records), Ageing research reviews (12 records), Biogerontology (10 records), Frontiers in immunology (10 records), International journal of molecular sciences (8 records). That journal breakdown describes the captured snapshot rather than the full index, and is offered as an orientation to where this field publishes, not as a complete ranking.

What this register does not establish

A record count is not evidence of benefit, and being indexed is not endorsement by anyone, including us. This page carries no effect estimate, no comparison between treatments, no dose and no recommendation. A large literature can be large because a question is hard, commercially interesting, or repeatedly studied at low quality, and a captured subset can over-represent whichever records the index returned first. Anyone using this register to decide what to take or which practitioner to see is using it for something it was not built to do.

Anchor records and how to verify them

Each register names anchor records that a reader can resolve independently: Ageing research reviews (2026); Apoptosis : an international journal on programmed cell death (2026); Biochimica et biophysica acta. Reviews on cancer (2026); Cellular and molecular life sciences : CMLS (2026). Anchors are selected deterministically, favouring reviews and trials, then open access, then citation count, with one record per journal. Records carrying a retraction or withdrawal notice in the index are excluded. Every anchor carries a DOI, its indexed grant support and its correction state as observed on 2026-08-08. Before this page was published, an independent review lane resolved every source URL listed below and recorded the hash of what it received.

Machine-readable reviewed statements

CLM-EVREG-CELLULAR-SENESCENCE-001

The Europe PMC search index reports 47,814 records for the query “"cellular senescence" AND FIRST_PDATE:[2020-01-01 TO 2026-08-08]”, resolved on 2026-08-08.

Evidence class: bibliographic index count

Sources: SRC-EPMC-INDEX-CELLULAR-SENESCENCE

CLM-EVREG-CELLULAR-SENESCENCE-002

Of those records, the index types 15,497 as a review or meta-analysis, resolved on 2026-08-08.

Evidence class: bibliographic index count

Sources: SRC-EPMC-REVIEWS-CELLULAR-SENESCENCE

CLM-EVREG-CELLULAR-SENESCENCE-003

The index types 144 of those records as a randomised controlled trial, resolved on 2026-08-08.

Evidence class: bibliographic index count

Sources: SRC-EPMC-TRIALS-CELLULAR-SENESCENCE

CLM-EVREG-CELLULAR-SENESCENCE-004

36,775 of those records are flagged open access, meaning their full text can be read without payment, resolved on 2026-08-08.

Evidence class: bibliographic index count

Sources: SRC-EPMC-OPENACCESS-CELLULAR-SENESCENCE

CLM-EVREG-CELLULAR-SENESCENCE-101

Ageing research reviews published the record titled “Effects of nutritional interventions on biomarkers of cellular senescence in humans: A systematic review” in 2026 under DOI 10.1016/j.arr.2026.103224.

Evidence class: bibliographic record

Sources: SRC-EPMC-CELLULAR-SENESCENCE-01

CLM-EVREG-CELLULAR-SENESCENCE-102

Apoptosis : an international journal on programmed cell death published the record titled “Mitochondrial dysfunction and cellular senescence drive accelerated gestational aging in spontaneous preterm birth: a narrative review” in 2026 under DOI 10.1007/s10495-026-02394-z.

Evidence class: bibliographic record

Sources: SRC-EPMC-CELLULAR-SENESCENCE-02

CLM-EVREG-CELLULAR-SENESCENCE-103

Biochimica et biophysica acta. Reviews on cancer published the record titled “Regulation of tumorigenesis by cellular senescence: Mechanisms and pathways in liver cancer and cholangiocarcinoma” in 2026 under DOI 10.1016/j.bbcan.2026.189657.

Evidence class: bibliographic record

Sources: SRC-EPMC-CELLULAR-SENESCENCE-03

CLM-EVREG-CELLULAR-SENESCENCE-104

Cellular and molecular life sciences : CMLS published the record titled “Cellular senescence and aging: molecular mechanisms and convergent pathways” in 2026 under DOI 10.1007/s00018-026-06317-8.

Evidence class: bibliographic record

Sources: SRC-EPMC-CELLULAR-SENESCENCE-04

Sources and governing contracts

  • SRC-EPMC-INDEX-CELLULAR-SENESCENCE — Europe PMC, EMBL-EBI, Europe PMC search index, records of any type: "cellular senescence" AND FIRST_PDATE:[2020-01-01 TO 2026-08-08]. Role: bibliographic index. Public literature index operated by EMBL-EBI. Metatron Health has no commercial or editorial relationship with the index operator and receives no payment connected to what it indexes. Open source
  • SRC-EPMC-REVIEWS-CELLULAR-SENESCENCE — Europe PMC, EMBL-EBI, Europe PMC search index, records typed as a review or meta-analysis: "cellular senescence" AND FIRST_PDATE:[2020-01-01 TO 2026-08-08] AND PUB_TYPE:"Review". Role: bibliographic index. Public literature index operated by EMBL-EBI. Metatron Health has no commercial or editorial relationship with the index operator and receives no payment connected to what it indexes. Open source
  • SRC-EPMC-TRIALS-CELLULAR-SENESCENCE — Europe PMC, EMBL-EBI, Europe PMC search index, records typed as a randomised controlled trial: "cellular senescence" AND FIRST_PDATE:[2020-01-01 TO 2026-08-08] AND PUB_TYPE:"Randomized Controlled Trial". Role: bibliographic index. Public literature index operated by EMBL-EBI. Metatron Health has no commercial or editorial relationship with the index operator and receives no payment connected to what it indexes. Open source
  • SRC-EPMC-OPENACCESS-CELLULAR-SENESCENCE — Europe PMC, EMBL-EBI, Europe PMC search index, records whose full text is free to read: "cellular senescence" AND FIRST_PDATE:[2020-01-01 TO 2026-08-08] AND OPEN_ACCESS:y. Role: bibliographic index. Public literature index operated by EMBL-EBI. Metatron Health has no commercial or editorial relationship with the index operator and receives no payment connected to what it indexes. Open source
  • SRC-EPMC-CELLULAR-SENESCENCE-01 — Ageing research reviews, Effects of nutritional interventions on biomarkers of cellular senescence in humans: A systematic review. Role: independent research. Independent peer-reviewed article. Metatron Health has no financial or editorial relationship with its authors, journal or funders and earns nothing from citing it. Open source
  • SRC-EPMC-CELLULAR-SENESCENCE-02 — Apoptosis : an international journal on programmed cell death, Mitochondrial dysfunction and cellular senescence drive accelerated gestational aging in spontaneous preterm birth: a narrative review. Role: independent research. Independent peer-reviewed article. Metatron Health has no financial or editorial relationship with its authors, journal or funders and earns nothing from citing it. Open source
  • SRC-EPMC-CELLULAR-SENESCENCE-03 — Biochimica et biophysica acta. Reviews on cancer, Regulation of tumorigenesis by cellular senescence: Mechanisms and pathways in liver cancer and cholangiocarcinoma. Role: independent research. Independent peer-reviewed article. Metatron Health has no financial or editorial relationship with its authors, journal or funders and earns nothing from citing it. Open source
  • SRC-EPMC-CELLULAR-SENESCENCE-04 — Cellular and molecular life sciences : CMLS, Cellular senescence and aging: molecular mechanisms and convergent pathways. Role: independent research. Independent peer-reviewed article. Metatron Health has no financial or editorial relationship with its authors, journal or funders and earns nothing from citing it. Open source

Reviewed: 2026-08-08 · Publication: four independent review lanes

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