Research · Evidence register · Epigenetic inheritance

Epigenetic inheritance: indexed research register 2020–2026

The Europe PMC index holds 3,625 records for epigenetic inheritance published between 2020 and 2026, of which 1,433 are typed as reviews and 3 as randomised controlled trials. This register reports what the literature contains and how to reach it, never whether a practice works.

Indexed records
3625
Reviews
1433
Trials
3
Open access
2755

Article overview

A provenance-preserving register of the peer-reviewed literature Europe PMC indexes for epigenetic inheritance, with publication types, journal spread and anchor records that any reader can resolve by DOI.

What this register counts

This page reports how much peer-reviewed literature is indexed on epigenetic inheritance, not what that literature concludes. Every headline number comes from a live query against the whole Europe PMC index for the term “epigenetic inheritance”, restricted to a first publication date between 2020-01-01 and 2026-08-17, and each query is published as a link you can open and re-run. On 2026-08-17 the term resolved to 3,625 records. These are complete counts over the index, not estimates and not a sample. A catalogue count is still a measurement of a catalogue, and a catalogue is not the state of knowledge.

Publication types and access

Publication type comes from the index metadata rather than from any reading of the articles. Of the 3,625 records, the index types 1,433 as a review or meta-analysis and 3 as a randomised controlled trial. 2,755 records are flagged open access, which means their full text can be read without payment and a reader can check any statement against the source. Records may carry more than one type, and records with no type assigned are counted in the total but in neither category, so the categories do not sum to the total and were never intended to.

How the literature is distributed

Counts by publication year run 2020: 422, 2021: 520, 2022: 561, 2023: 546, 2024: 549, 2025: 684, 2026: 333, with 2025 the heaviest year in the window. Within the 217 records Metatron Health holds in its dated local snapshot of 2026-08-17, the literature spans 138 distinct journals, led by: International journal of molecular sciences (11 records), Nature communications (6 records), Frontiers in plant science (4 records), Frontiers in endocrinology (3 records), Biology (3 records). That journal breakdown describes the captured snapshot rather than the full index, and is offered as an orientation to where this field publishes, not as a complete ranking.

What this register does not establish

A record count is not evidence of benefit, and being indexed is not endorsement by anyone, including us. This page carries no effect estimate, no comparison between treatments, no dose and no recommendation. A large literature can be large because a question is hard, commercially interesting, or repeatedly studied at low quality, and a captured subset can over-represent whichever records the index returned first. Anyone using this register to decide what to take or which practitioner to see is using it for something it was not built to do.

Anchor records and how to verify them

Each register names anchor records that a reader can resolve independently: Biomolecules (2026); The Journal of experimental biology (2026); Clinical epigenetics (2026); Proceedings of the National Academy of Sciences of the United States of America (2026). Anchors are selected deterministically, favouring reviews and trials, then open access, then citation count, with one record per journal. Records carrying a retraction or withdrawal notice in the index are excluded. Every anchor carries a DOI, its indexed grant support and its correction state as observed on 2026-08-17. Before this page was published, an independent review lane resolved every source URL listed below and recorded the hash of what it received.

Machine-readable reviewed statements

CLM-EVREG-EPIGENETIC-INHERITANCE-001

The Europe PMC search index reports 3,625 records for the query “"epigenetic inheritance" AND FIRST_PDATE:[2020-01-01 TO 2026-08-17]”, resolved on 2026-08-17.

Evidence class: bibliographic index count

Sources: SRC-EPMC-INDEX-EPIGENETIC-INHERITANCE

CLM-EVREG-EPIGENETIC-INHERITANCE-002

Of those records, the index types 1,433 as a review or meta-analysis, resolved on 2026-08-17.

Evidence class: bibliographic index count

Sources: SRC-EPMC-REVIEWS-EPIGENETIC-INHERITANCE

CLM-EVREG-EPIGENETIC-INHERITANCE-003

The index types 3 of those records as a randomised controlled trial, resolved on 2026-08-17.

Evidence class: bibliographic index count

Sources: SRC-EPMC-TRIALS-EPIGENETIC-INHERITANCE

CLM-EVREG-EPIGENETIC-INHERITANCE-004

2,755 of those records are flagged open access, meaning their full text can be read without payment, resolved on 2026-08-17.

Evidence class: bibliographic index count

Sources: SRC-EPMC-OPENACCESS-EPIGENETIC-INHERITANCE

CLM-EVREG-EPIGENETIC-INHERITANCE-101

Biomolecules published the record titled “Germline and Embryonic Mechanisms in the Epigenetic Inheritance of Neurodevelopmental and Cognitive Traits in Mammals” in 2026 under DOI 10.3390/biom16050669.

Evidence class: bibliographic record

Sources: SRC-EPMC-EPIGENETIC-INHERITANCE-01

CLM-EVREG-EPIGENETIC-INHERITANCE-102

The Journal of experimental biology published the record titled “Exploring epigenetic inheritance: alternative models and experimental approaches” in 2026 under DOI 10.1242/jeb.251062.

Evidence class: bibliographic record

Sources: SRC-EPMC-EPIGENETIC-INHERITANCE-02

CLM-EVREG-EPIGENETIC-INHERITANCE-103

Clinical epigenetics published the record titled “Sperm tRNA-derived fragments: molecular mechanisms and clinical implications for paternal epigenetic inheritance” in 2026 under DOI 10.1186/s13148-026-02155-4.

Evidence class: bibliographic record

Sources: SRC-EPMC-EPIGENETIC-INHERITANCE-03

CLM-EVREG-EPIGENETIC-INHERITANCE-104

Proceedings of the National Academy of Sciences of the United States of America published the record titled “Testicular origin of epigenetic inheritance independent of sperm mitochondrial DNA and epididymal exposure” in 2026 under DOI 10.1073/pnas.2611096123.

Evidence class: bibliographic record

Sources: SRC-EPMC-EPIGENETIC-INHERITANCE-04

Sources and governing contracts

  • SRC-EPMC-INDEX-EPIGENETIC-INHERITANCE — Europe PMC, EMBL-EBI, Europe PMC search index, records of any type: "epigenetic inheritance" AND FIRST_PDATE:[2020-01-01 TO 2026-08-17]. Role: bibliographic index. Public literature index operated by EMBL-EBI. Metatron Health has no commercial or editorial relationship with the index operator and receives no payment connected to what it indexes. Open source
  • SRC-EPMC-REVIEWS-EPIGENETIC-INHERITANCE — Europe PMC, EMBL-EBI, Europe PMC search index, records typed as a review or meta-analysis: "epigenetic inheritance" AND FIRST_PDATE:[2020-01-01 TO 2026-08-17] AND PUB_TYPE:"Review". Role: bibliographic index. Public literature index operated by EMBL-EBI. Metatron Health has no commercial or editorial relationship with the index operator and receives no payment connected to what it indexes. Open source
  • SRC-EPMC-TRIALS-EPIGENETIC-INHERITANCE — Europe PMC, EMBL-EBI, Europe PMC search index, records typed as a randomised controlled trial: "epigenetic inheritance" AND FIRST_PDATE:[2020-01-01 TO 2026-08-17] AND PUB_TYPE:"Randomized Controlled Trial". Role: bibliographic index. Public literature index operated by EMBL-EBI. Metatron Health has no commercial or editorial relationship with the index operator and receives no payment connected to what it indexes. Open source
  • SRC-EPMC-OPENACCESS-EPIGENETIC-INHERITANCE — Europe PMC, EMBL-EBI, Europe PMC search index, records whose full text is free to read: "epigenetic inheritance" AND FIRST_PDATE:[2020-01-01 TO 2026-08-17] AND OPEN_ACCESS:y. Role: bibliographic index. Public literature index operated by EMBL-EBI. Metatron Health has no commercial or editorial relationship with the index operator and receives no payment connected to what it indexes. Open source
  • SRC-EPMC-EPIGENETIC-INHERITANCE-01 — Biomolecules, Germline and Embryonic Mechanisms in the Epigenetic Inheritance of Neurodevelopmental and Cognitive Traits in Mammals. Role: independent research. Independent peer-reviewed article. Metatron Health has no financial or editorial relationship with its authors, journal or funders and earns nothing from citing it. Open source
  • SRC-EPMC-EPIGENETIC-INHERITANCE-02 — The Journal of experimental biology, Exploring epigenetic inheritance: alternative models and experimental approaches. Role: independent research. Independent peer-reviewed article. Metatron Health has no financial or editorial relationship with its authors, journal or funders and earns nothing from citing it. Open source
  • SRC-EPMC-EPIGENETIC-INHERITANCE-03 — Clinical epigenetics, Sperm tRNA-derived fragments: molecular mechanisms and clinical implications for paternal epigenetic inheritance. Role: independent research. Independent peer-reviewed article. Metatron Health has no financial or editorial relationship with its authors, journal or funders and earns nothing from citing it. Open source
  • SRC-EPMC-EPIGENETIC-INHERITANCE-04 — Proceedings of the National Academy of Sciences of the United States of America, Testicular origin of epigenetic inheritance independent of sperm mitochondrial DNA and epididymal exposure. Role: independent research. Independent peer-reviewed article. Metatron Health has no financial or editorial relationship with its authors, journal or funders and earns nothing from citing it. Open source

Reviewed: 2026-08-17 · Publication: four independent review lanes

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