Botanical species · safety record

Abrus precatorius

The EFSA Compendium of Botanicals holds 6 constituent measurements and 10 adverse-effect records for Abrus precatorius. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Abrus precatorius L.

6Constituent measurements

10Safety records

10Cited sources

4Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 4 licensed products naming Abrus precatorius as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

Seed
Seed(s)

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Abrin	Seed	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Abrin	Seed	Drying (dehydration)	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Alkaloids	Leaves	Solvent extraction	—	Phytochemical screening	No resolvable identifier
L-hypaphorine	Seed	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Saponins	Leaves	Solvent extraction	—	Phytochemical screening	No resolvable identifier
Tannins	Leaves	Solvent extraction	—	Phytochemical screening	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Digestive	Seed	—	—	Case report	Resolve DOI
Neurotoxicity	Brain	Seed	—	Human (as organism)	Case report	Resolve DOI
Neurotoxicity	Brain	Seed	—	Human (as organism)	Case report	Resolve DOI
Pulmonary and cardiac	Heart	Seed	—	Human (as organism)	Case report	Resolve DOI
Systemic	Digestive	Seed	—	Human (as organism)	Case report	Resolve DOI
Digestive	Digestive	Seed	—	Human (as organism)	Case report	No resolvable identifier
Reproductive	Uterus	Seed	Solvent extraction	Rat (as animal)	Reproduction toxicity	No resolvable identifier
Systemic	—	Leaves	Solvent extraction	Rat (as animal)	Acute toxicity	No resolvable identifier
Systemic	—	Leaves	Solvent extraction	Rat (as animal)	Acute toxicity	No resolvable identifier
Systemic	Blood coagulation	Seed	Solvent extraction	Rat (as animal)	Acute toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Alhamdani, Mazin., Brown, Brande., Narula, Pramod. Abrin Poisoning in an 18-Month-Old Child. American journal of case reports, 2015, vol. 16, p. 146-148.
Ganesan, R., Ettiyan, R. Abrus precatorius induced hemorrhagic colitis. American journal of pharmacology and toxicology, 2015, vol. 10, no. 2, p. 40-45. DOI
Ogbuehi, Ijeoma H., Ebong, Omotayo O., Obianime, Atuboyedia W. Oral acute toxicity (LD50) study of different solvent extracts of Abrus precatorius Linn leaves in wistar rats.. European journal of experimental biology, 2015, vol. 5, no. 1, p. 18-25.
Johri, P. K., Tiwari, Divya., Johri, Reeta. RESORPTION/ABORTIFACIENT AND TERATOGENIC ACTIVITY OF SELECTED INDIGENOUS MEDICINAL PLANTS IN FEMALE ALBINO RATS . Biochemical and cellular archives, 2009, vol. 9, no. 2, p. 211-216.
Martinez, N., Ang�lica, A., Mariana, A., Rosa, B., Edmundo, C. Toxic effects of Abrus precatorius L. seeds on laboratory rats. Emirates journal of food and agriculture, 2012, vol. 24, no. 2, p. 159-164.
Sahoo, Ratnakar., Hamide, Abdoul., Amalnath, S. Deepak., Narayana, B. Srikant. Acute demyelinating encephalitis due to Abrus precatorius poisoning - complete recovery after steroid therapy . Clinical toxicology, 2008, vol. 46, no. 10, p. 1071-1073. DOI
Wooten, Joe Valentine., Pittman, Christopher T., Blake, Thomas A., Thomas, Jerry D., Devlin, John J., Higgerson, Renee A., Johnson, Rudolph C. A case of abrin toxin poisoning, confirmed via quantitation of L-abrine (N-methyl-L-tryptophan) biomarker. . Journal of medical toxicology : official journal of the american college of medical toxicology, 2014, vol. 10, no. 4, p. 392-4. DOI
Karthikeyan, Aishwarya., Amalnath, S. Deepak. Abrus precatorius Poisoning: A Retrospective Study of 112 Patients. Indian journal of critical care medicine, 2017, vol. 21, no. 4, p. 224-225. DOI
Lin, Jung-Yaw., Yan, Tyan-Fuh., Ting, Ling-Pai., Tung, Ta-Cheng. Toxic and nontoxic lectins from Abrus precatorius and Ricinus communis.. Toxicon, 1978, vol. Suppl. 1, no. Toxins: Anim., Plant Microb., p. 837-53.
Singh, G D., Banerji, R., Mahrotra, S. Effect of shodhana on the toxicity of abrus precatorius.. Ancient science of life, 1998, vol. 18, no. 2, p. 127-9.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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