Botanical species · safety record

Achillea fragrantissima

The EFSA Compendium of Botanicals holds 12 constituent measurements and 3 adverse-effect records for Achillea fragrantissima. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Achillea fragrantissima (Forssk.) Sch.Bip.

12Constituent measurements

3Safety records

7Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
1,8-cineole	Unspecified	Essential oil	≤ 1.25 Percent	GC*GC/MS	Resolve DOI
Alpha-thujone	Unspecified	Essential oil	≥ 25.54 Percent	GC*GC/MS	Resolve DOI
Alpha-thujone	Unspecified	Essential oil	≤ 36.5 Percent	GC*GC/MS	Resolve DOI
Artemisia ketone	Unspecified	Essential oil	≥ 13.15 Percent	GC*GC/MS	Resolve DOI
Artemisia ketone	Unspecified	Essential oil	≤ 23.77 Percent	GC*GC/MS	Resolve DOI
Beta-thujone	Unspecified	Essential oil	≥ 6.63 Percent	GC*GC/MS	Resolve DOI
Beta-thujone	Unspecified	Essential oil	≤ 11.55 Percent	GC*GC/MS	Resolve DOI
Germacranolide	Aerial part of plants	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Saponins	Live plants	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Sesquiterpene lactones	Aerial part of plants	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Epoxides	Aerial part of plants	Essential oil	1.54 Percent	GC-MS	No resolvable identifier
Tannins	Unspecified	Solvent extraction	36.62 Percent	Phytochemical screening	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Digestive	Aerial part of plants	Solvent extraction	—	In vitro	Resolve DOI
Digestive	Digestive	Aerial part of plants	Solvent extraction	—	In vitro	Resolve DOI
Digestive	Digestive	Aerial part of plants	Solvent extraction	—	In vitro	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Al-Harbi, K.B., El-Tigani-asil, E.A., Ahmed, A.F., El-Ashmawy, I.M., Al-Wabel, N.A. Wound healing potential of methanolic extracts of some plants native to Al-Qassim region, Saudi Arabia. Journal of food, agriculture and environment, 2016, vol. 14, no. 3-4, p. 18-22.
Elmann, Anat., Telerman, Alona., Ofir, Rivka., Kashman, Yoel. Glutamate Toxicity to Differentiated Neuroblastoma N2a Cells Is Prevented by the Sesquiterpene Lactone Achillolide A and the Flavonoid 3,5,4'-Trihydroxy-6,7,3'-Trimethoxyflavone from Achillea fragrantissima . Journal of molecular neuroscience, 2017, vol. 62, no. 1, p. 99-105. DOI
Mustafa, E., Abdalla, S., Abu Zarga, M., Sabri, S. Constituents of Achillae fragrantissima and effects of 13-O-desacetyl-1-beta-hydroxyafragloucolide on rat isolated smooth muscle. Fitoterapia, 1992, vol. 63, no. 6, p. 526-533.
Abu-Hamdah, S., Afifi, FU., Shehadeh, M., Khalid, S. Simple quality-control procedures for selected medicinal plants commonly used in Jordan . Pharmaceutical biology, 2005, vol. 43, no. 1, p. 1-7. DOI
SEGAL, R., DOR, A., DUDDECK, H., SNATZKE, G., ROSENBAUM, D., KAJTAR, M. THE SESQUITERPENE LACTONES FROM ACHILLEA FRAGRANTISSIMA .1. ACHILLOLIDE-A AND ACHILLOLIDE-B, 2 NOVEL GERMACRANOLIDES . Tetrahedron, 1987, vol. 43, no. 18, p. 4125-4132. DOI
Fleisher, Z., Fleisher, A. Volatiles of Achillea fragrantissima (Forssk.) Sch. Bip.: Aromatic plants of the holy land and the Sinai. Part XI. Journal of essential oil research, 1993, vol. 5, no. 2, p. 211-214. DOI
Ezzat, Shahira M., Salama, Maha M. A new a-glucosidase inhibitor from Achillea fragrantissima ( Forssk.) Sch Bip. growingin Egypt . Natural product research, 2014, vol. 28, no. 11, p. 812-818. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature