Botanical species · safety record

Aconitum chasmanthum

The EFSA Compendium of Botanicals holds 8 constituent measurements and 2 adverse-effect records for Aconitum chasmanthum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Aconitum chasmanthum Stapf ex Holmes

8Constituent measurements

2Safety records

6Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Live plants	Solvent extraction	—	IR and Raman Spectroscopy	Resolve DOI
Norditerpene alkaloids	Roots and other underground parts	Solvent extraction	—	IR and Raman Spectroscopy	Resolve DOI
Aconitine	Roots and other underground parts	Drying (dehydration)	≤ 0.032 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Aconitine	Roots and other underground parts	Solvent extraction	≥ 0.509 Percent	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Aconitine	Roots and other underground parts	Solvent extraction	≤ 0.531 Percent	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Aconitine	Roots and other underground parts	Drying (dehydration)	≥ 0.031 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Norditerpene alkaloids	Unspecified	Solvent extraction	≤ 3.8 Percent	Unspecified	No resolvable identifier
Norditerpene alkaloids	Unspecified	Solvent extraction	≥ 0.6 Percent	Unspecified	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Nephrotoxicity	Urogenital: kidneys	Roots and other underground parts	Drying (dehydration)	Rat (as animal)	Chronic/long term toxicity	Resolve DOI
Systemic	Cardiovascular / haematological	Roots and other underground parts	Drying (dehydration)	Rat (as animal)	Chronic/long term toxicity	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Wahid, M. A., Samiullah. Standardization of active principles of indigenous pharmacopoeial drugs found in West Pakistan. Pakistan journal of scientific and industrial research, 1960, vol. 3, p. 228-30.
Parvez, M., Gul, W., Anwar, S., Miana, GA., Atta-ur-Rahman., Choudhary, MI. Chasmaconitine 0.5-methanol solvate. Acta crystallographica section c-crystal structure communications, 1998, vol. 54, p. 236-238. DOI
Jabeen, Neelofar., Shakeel-u-Rehman., Bhat, Khursheed A., Khuroo, Mohd .A., Shawl, Abdul S. Quantitative determination of aconitine in Aconitum chasmanthum and Aconitum heterophyllum from Kashmir Himalayas using HPLC.. Journal of pharmacy research, 2011, vol. 4, no. 8, p. 2471-2473.
Kannan, L. V., Srivastava, S. K., Ray, G. K. Estimation of alkaloids in aconite root and its tincture.. Indian journal of pharmacy, 1961, vol. 23, p. 212-13.
Samusenko, L.N., Razakova, D.M., Bessonova, I.A., Gorelova, A.P. Alkaloids of the cultivated species Aconitum chasmanthum and Delphinium elatum. Chemistry of Natural Compounds, 1992, vol. 28, no. 1, p. 125-126. DOI
Sarkar, P K., Prajapati, P K., Shukla, V J., Ravishankar, B. Effect of shodhana treatment on chronic toxicity and recovery of aconite. . Toxicology international, 2012, vol. 19, no. 1, p. 35-41. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature