Botanical species · safety record
Aconitum ferox
The EFSA Compendium of Botanicals holds 5 constituent measurements and 2 adverse-effect records for Aconitum ferox. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Aconitum ferox Wall. ex Ser.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 5 licensed products naming Aconitum ferox as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Source material stated
What the records describe
Constituents measured
- Aconitine3
- Alkaloids1
- Norditerpene alkaloids1
Plant parts
- Roots and other underground parts4
- Leaves1
- Unspecified1
Preparations
- Solvent extraction6
- Thermal treatment (heating for preservation)1
Effect types
- Systemic2
Target tissues
- Neurologic1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Norditerpene alkaloids | Roots and other underground parts | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Aconitine | Leaves | Solvent extraction | ≥ 0.2 Percent | Unspecified | No resolvable identifier |
| Aconitine | Roots and other underground parts | Solvent extraction | 0.2107 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
| Aconitine | Roots and other underground parts | Solvent extraction | ≥ 0.3 Percent | Unspecified | No resolvable identifier |
| Alkaloids | Unspecified | Solvent extraction | 1.1 Percent | Colorimetry, Spectroscopy (Spectrometry) and Photometry | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Systemic | — | Roots and other underground parts | Solvent extraction | Rat (as animal) | Acute toxicity | Resolve DOI |
| Systemic | Neurologic | — | Thermal treatment (heating for preservation) | Human (as organism) | Other | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- HANUMAN, JB., KATZ, A. ISOLATION AND IDENTIFICATION OF 4 NORDITERPENOID ALKALOIDS FROM PROCESSED AND UNPROCESSED ROOT TUBERS OF ACONITUM-FEROX . Journal of natural products, 1993, vol. 56, no. 6, p. 801-809. DOI
- Deore, S L., Moon, K V., Khadabadi, S S., Deokate, U A., Baviskar, B A. Evaluation of toxicity of 'Vatsanabha' (Aconitum ferox, Ranunculaceae) Before and After Shodhana. . Journal of young pharmacists : jyp, 2013, vol. 5, no. 1, p. 3-6. DOI
- Tomar, Brijendra Singh., Vishen, Archana Singh. Vatsnabha- a wonderful poisonous drug.. International journal of ayurveda and pharmaceutical chemistry, 2015, vol. 2, no. 2, p. 17-22.
- Mol, V. C. Jiji., Shanmugapriya, P. SCIENTIFIC VALIDATION ON SIDDHA PURIFICATION PROCESS OF NABHI. International journal of pharmaceutical sciences and research, 2017, vol. 8, no. 4, p. 1790-1795.
- Bessonova, I. A., Saidkhodzhaeva, Sh. A., Usmanova, S. K. Alkaloids of cultivated species of Aconitum paniculatum and A. ferox.. Khimiya prirodnykh soedinenii, 1995, no. 6, p. 914-915.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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