Botanical species · safety record
Aconitum napellus
The EFSA Compendium of Botanicals holds 5 constituent measurements and 2 adverse-effect records for Aconitum napellus. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Aconitum napellus L.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 291 licensed products naming Aconitum napellus as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
What the records describe
Constituents measured
- Aconitine3
- Diterpene alkaloids1
- Lycoctonine1
Plant parts
- Unspecified2
- Flower1
- Roots and other underground parts1
Preparations
- Solvent extraction2
- Drying (dehydration)1
- Fresh1
Effect types
- Pulmonary and cardiac2
Target tissues
- Lung1
- Neurologic: central nervous system1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Aconitine | Unspecified | Solvent extraction | ≥ 0.042 Percent | Unspecified | No resolvable identifier |
| Aconitine | Unspecified | Solvent extraction | ≤ 0.104 Percent | Unspecified | No resolvable identifier |
| Aconitine | — | — | — | LC-MS | No resolvable identifier |
| Diterpene alkaloids | — | — | — | LC-MS | No resolvable identifier |
| Lycoctonine | — | — | — | LC-MS | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Pulmonary and cardiac | Lung | Flower | Fresh | Human (as organism) | Case report | Resolve DOI |
| Pulmonary and cardiac | Neurologic: central nervous system | Roots and other underground parts | Drying (dehydration) | Human (as organism) | Case report | Resolve DOI |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Burmann, J. Annual Variations in the Amount of Active Principles of Certain Medicinal Plants.. Zzz, 1911, vol. 49, p. 6-9.
- Pullela, Ravi., Young, Lorraine., Gallagher, Barry., Avis, Simon P., Randell, Edward W. A case of fatal aconitine poisoning by monkshood ingestion. Journal of forensic sciences, 2008, vol. 53, no. 2, p. 491-494. DOI
- Puschner, B., Booth, MC., Tor, ER., Odermatt, A. Diterpenoid alkaloid toxicosis in cattle in the Swiss Alps. Veterinary and human toxicology, 2002, vol. 44, no. 1, p. 8-10.
- Moritz, F., Compagnon, P., Kaliszczak, IG., Kaliszczak, Y., Caliskan, V., Girault, C. Severe acute poisoning with homemade Aconitum napellus capsules: Toxicokinetic and clinical data . Clinical toxicology, 2005, vol. 43, no. 7, p. 873-876. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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