Botanical species · safety record

Adenium obesum

The EFSA Compendium of Botanicals holds 11 constituent measurements for Adenium obesum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Adenium obesum (Forssk.) Roem. & Schult.

11Constituent measurements
0Safety records
7Cited sources
0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Cardiac glycosides4
  • 16-anhydrogitoxigenin2
  • Pregnane derivatives2
  • Alkaloids1
  • Isoquercitrin1
  • Saponins1

Plant parts

  • Roots and other underground parts3
  • Stem3
  • stalk3
  • Fruit unspecified2
  • Leaves2
  • Bark1

Preparations

  • Solvent extraction11

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
16-anhydrogitoxigeninRoots and other underground partsSolvent extraction—Nuclear Magnetic Resonance (NMR)Resolve DOI
16-anhydrogitoxigeninStem / stalkSolvent extraction—Nuclear Magnetic Resonance (NMR)Resolve DOI
AlkaloidsFruit unspecifiedSolvent extraction—Nuclear Magnetic Resonance (NMR)Resolve DOI
Cardiac glycosidesLeavesSolvent extraction—HPLC with standard detection methodsResolve DOI
Cardiac glycosidesFruit unspecifiedSolvent extraction—Nuclear Magnetic Resonance (NMR)Resolve DOI
IsoquercitrinLeavesSolvent extraction0.26 Milligram/gramHPLC-UVResolve DOI
Cardiac glycosidesRoots and other underground partsSolvent extraction—Nuclear Magnetic Resonance (NMR)No resolvable identifier
Cardiac glycosidesStem / stalkSolvent extraction—Nuclear Magnetic Resonance (NMR)No resolvable identifier
Pregnane derivativesRoots and other underground partsSolvent extraction—Nuclear Magnetic Resonance (NMR)No resolvable identifier
Pregnane derivativesStem / stalkSolvent extraction—Nuclear Magnetic Resonance (NMR)No resolvable identifier
SaponinsBarkSolvent extraction—Phytochemical screeningNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Versiani, Muhammad Ali., Ahmed, Salman Khalid., Ikram, Ambreen., Ali, Syed Tahir., Yasmeen, Kousar., Faizi, Shaheen. Chemical Constituents and Biological Activities of Adenium obesum (Forsk.) Roem. et Schult. . Chemistry & biodiversity, 2014, vol. 11, no. 2, p. 171-180. DOI
  2. Arai, Midori A., Tateno, Chikashi., Koyano, Takashi., Kowithayakorn, Thaworn., Kawabe, Seiichiro., Ishibashi, Masami. New hedgehog/GLI-signaling inhibitors from Adenium obesum. Organic & biomolecular chemistry, 2011, vol. 9, no. 4, p. 1133-1139. DOI
  3. Meda, N. R., Fraisse, D., Gnoula, C., Peyrode, C., Texier, O., Senejoux, F., Felgines, C. Characterization and Quantification of Polyphenolic Compounds from Adenium Obesum Leaves . Chemistry of natural compounds, 2016, vol. 52, no. 1, p. 134-135. DOI
  4. Ahmed, Salman Khalid., Versiani, Muhammad Ali., Ikram, Ambreen., Sattar, Samina Abdul., Faizi, Shaheen. Cytotoxic cardiac glycosides from the fruit (pods) of Adenium obesum (Forssk.) Roem. & Schult . Natural product research, 2017, vol. 31, no. 10, p. 1205-1208. DOI
  5. VETHAVIYASAR, N., JOHN, D. 16-ANHYDRO-3-ACETYL-GITOXIGENIN IN ADENIUM-OBESUM. Planta medica, 1982, vol. 44, no. 2, p. 123-124. DOI
  6. YAMAUCHI, T., ABE, F. CARDIAC-GLYCOSIDES AND PREGNANES FROM ADENIUM-OBESUM (STUDIES ON THE CONSTITUENTS OF ADENIUM .1.) . Chemical & pharmaceutical bulletin, 1990, vol. 38, no. 3, p. 669-672.
  7. ALYAHYA, MA., MOSSA, JS., TARIQ, M., ALMESHAL, IA., ALBADR, AA. PHYTOTOXICITY STUDIES ON SAUDI PLANTS. Toxicon, 1987, vol. 25, no. 4, p. 363-364.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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