Botanical species · safety record

Adonis aestivalis

The EFSA Compendium of Botanicals holds 7 constituent measurements and 2 adverse-effect records for Adonis aestivalis. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Adonis aestivalis L.

7Constituent measurements

2Safety records

5Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Corytuberine	Aerial part of plants	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Helveticoside	Aerial part of plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Magnoflorine	Aerial part of plants	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Periplogenin	Aerial part of plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Cardenolides	Seed	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Cymarin	Aerial part of plants	Drying (dehydration)	—	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	No resolvable identifier
Strophantidin	Seed	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Digestive	Aerial part of plants	Fresh	Horse (as animal)	Case report	Resolve DOI
Pulmonary and cardiac	Cardiovascular / haematological	Aerial part of plants	Fresh	Horse (as animal)	Case report	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

KOPP, B., KRENN, L., KUBELKA, E., KUBELKA, W. CARDENOLIDES FROM ADONIS-AESTIVALIS. PHYTOCHEMISTRY, 1992, vol. 31, no. 9, p. 3195-3198. DOI
Slavik, Jiri., Bochorakova, Jitka., Slavikova, Leonora. Occurrence of magnoflorine and corytuberine in some wild or cultivated plants of Czechoslovakia.. Collection of Czechoslovak Chemical Communications, 1987, vol. 52, no. 3, p. 804-11. DOI
KAVALALI, G. ISOLATION OF CYMARIN FROM ADONIS-AESTIVALIS. Lloydia-the journal of natural products, 1973, vol. 36, no. 4, p. 426-426.
Kubo, Satoshi., Kuroda, Minpei., Matsuo, Yukiko., Masatani, Daichi., Sakagami, Hiroshi., Mimaki, Yoshihiro. New Cardenolides from the Seeds of Adonis aestivalis. CHEMICAL & PHARMACEUTICAL BULLETIN, 2012, vol. 60, no. 10, p. 1275-1282.
Woods, LW., Filigenzi, MS., Booth, MC., Rodger, LD., Arnold, JS., Puschner, B. Summer pheasant's eye (Adonis aestivalis) poisoning in three horses. VETERINARY PATHOLOGY, 2004, vol. 41, no. 3, p. 215-220. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature