Botanical species · safety record

Adonis amurensis

The EFSA Compendium of Botanicals holds 19 constituent measurements for Adonis amurensis. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Adonis amurensis Regel & Radde

19Constituent measurements

0Safety records

9Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Cardenolide glycosides	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Cardenolides	Roots and other underground parts	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Convallatoxin	Aerial part of plants	Solvent extraction	—	—	Resolve DOI
Convalloside	Aerial part of plants	Solvent extraction	—	—	Resolve DOI
Cymarin	Aerial part of plants	Solvent extraction	—	—	Resolve DOI
Digitoxigenin	Aerial part of plants	Solvent extraction	—	—	Resolve DOI
Digitoxigenin	Aerial part of plants	Solvent extraction	—	Mass Spectroscopy and hyphenated methods without chromatography	Resolve DOI
Periplorhamnoside	Aerial part of plants	Solvent extraction	—	—	Resolve DOI
Pinoresinol	Aerial part of plants	Solvent extraction	—	—	Resolve DOI
Pregnane derivatives	Unspecified	—	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Somalin	Aerial part of plants	Solvent extraction	—	—	Resolve DOI
Strophantidin	Aerial part of plants	Solvent extraction	—	Mass Spectroscopy and hyphenated methods without chromatography	Resolve DOI
Strophantidin	Aerial part of plants	Solvent extraction	—	—	Resolve DOI
Cardenolide glycosides	Roots and other underground parts	—	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Convallatoxin	Aerial part of plants	Solvent extraction	≤ 0.14 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Convallatoxin	Aerial part of plants	Solvent extraction	≥ 0.0014 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Cymarin	Unspecified	—	—	HPLC with standard detection methods	No resolvable identifier
Scopoletin	Unspecified	—	—	—	No resolvable identifier
Umbelliferone	Unspecified	—	—	—	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Yin, L., Zhang, Y., Tian, H.-Y., Jiang, R.-W. Chemical constituents from Adonis amurensis. Chinese Traditional and Herbal Drugs, 2014, vol. 45, no. 23, p. 3361-3366. DOI
Liu, Juan., Cui, Xiangwei. Determination of convallatoxin content in the herba of Adonis amurensis Regel et Radde by HPLC.. Zhongcaoyao, 2007, vol. 38, no. 4, p. 617-618.
Ponomarenko, A.A., Komissarenko, N.F., Stukkei, K.L. Cardenolides of Adonis amurensis. Chemistry of Natural Compounds, 1971, vol. 7, no. 6, p. 833-834. DOI
Kubo, Satoshi., Kuroda, Minpei., Yokosuka, Akihito., Sakagami, Hiroshi., Mimaki, Yoshihiro. Amurensiosides L-P, Five New Cardenolide Glycosides from the Roots of Adonis amurensis. NATURAL PRODUCT COMMUNICATIONS, 2015, vol. 10, no. 1, p. 27-32.
Kuroda, Minpei., Kubo, Satoshi., Uchida, Shingo., Sakagami, Hiroshi., Mimaki, Yoshihiro. Amurensiosides A-K, 11 new pregnane glycosides from the roots of Adonis amurensis. STEROIDS, 2010, vol. 75, no. 1, p. 83-94. DOI
Sato, Yoshimasa., Hirano, Miho., Nitta, Isao., Azuma, Junko., Hayashi, Koji., Mitsuhashi, Hiroshi. Components of adonis plants.. Chemical & Pharmaceutical Bulletin, 1971, vol. 19, no. 1, p. 202-5. DOI
Nakayama, Mutsuo., Yamamoto, Akihiro., Shinohara, Ayako., Fujita, Yoshihiko., Kanbara, Keizo., Miyataka, Hideki. Analysis of poisonous substances [cymarin] in Adonis amurensis Regel et Radde by LC/MS.. Japanese Journal of Forensic Toxicology, 2002, vol. 20, no. 1, p. 34-41.
PONOMARE.AA., STUKKEI, KL., KOMISSAR.NF. COUMARINS OF ADONIS AMURENSIS. KHIMIYA PRIRODNYKH SOEDINENII, 1971, no. 5, p. 661-&.
Shimizu, Yuzuru., Sato, Yoshimasa., Mitsuhashi, Hiroshi. Isolation and structures of new pregnane derivatives from Adonis amurensis.. Chemical & Pharmaceutical Bulletin, 1969, vol. 17, no. 11, p. 2391-4. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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