Botanical species · safety record

Aegopodium podagraria

The EFSA Compendium of Botanicals holds 16 constituent measurements and 1 adverse-effect record for Aegopodium podagraria. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Aegopodium podagraria L.

16Constituent measurements
1Safety records
8Cited sources
2Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 2 licensed products naming Aegopodium podagraria as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

  • Aerial parts
  • Whole plant

What the records describe

Constituents measured

  • Falcarindiol4
  • Furanocoumarins2
  • Apterin1
  • Bergapten1
  • Daidzin1
  • Formononetin1
  • Isoformononetin1
  • Lectins1
  • Methoxsalen1
  • Methylisoeugenol1

Plant parts

  • Leaves11
  • Live plants2
  • Flower1
  • Roots and other underground parts1
  • Unspecified1

Preparations

  • Solvent extraction15
  • Drying (dehydration)1

Effect types

  • Reproductive1

Target tissues

  • Uterus1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
BergaptenLeavesSolvent extraction—GC-MSResolve DOI
FalcarindiolLeavesSolvent extraction—GC-MSResolve DOI
FalcarindiolLive plantsSolvent extraction≥ 5 Milligram/gramHPLC with standard detection methodsResolve DOI
FalcarindiolLive plantsSolvent extraction≤ 85 Milligram/gramHPLC with standard detection methodsResolve DOI
FalcarindiolFlowerSolvent extraction88 Milligram/gramHPLC with standard detection methodsResolve DOI
FuranocoumarinsLeavesSolvent extraction≤ 12 Microgram/millilitreNuclear Magnetic Resonance (NMR)Resolve DOI
FuranocoumarinsLeavesSolvent extraction≥ 3.1 Microgram/millilitreNuclear Magnetic Resonance (NMR)Resolve DOI
LectinsUnspecified——UnspecifiedResolve DOI
MethoxsalenLeavesSolvent extraction—GC-MSResolve DOI
MethylisoeugenolLeavesSolvent extraction—GC-MSResolve DOI
ApterinRoots and other underground partsSolvent extraction—Chromatographic testsNo resolvable identifier
DaidzinLeavesSolvent extraction—HPLC with standard detection methodsNo resolvable identifier
FormononetinLeavesSolvent extraction—HPLC with standard detection methodsNo resolvable identifier
IsoformononetinLeavesSolvent extraction—HPLC with standard detection methodsNo resolvable identifier
MyrceneLeavesSolvent extraction6.6 PercentGC-MSNo resolvable identifier
PrunetinLeavesSolvent extraction—HPLC with standard detection methodsNo resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
ReproductiveUterus—Drying (dehydration)House mouse (as animal)Acute toxicityNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Bergeron, Jean Marie., Goulet, Marie. Study on the phytoestrogenic and phytotoxic effects of open-land plants on the laboratory mouse.. Canadian journal of zoology, 1980, vol. 58, no. 9, p. 1575-81.
  2. Fischer, Frederik C., Svendsen, A. Baerheim. Apterin, a common furanocoumarin glycoside in the umbelliferae. Phytochemistry (elsevier), 1976, vol. 15, no. 6, p. 1079-80.
  3. Degen, T., Buser, HR., Stadler, E. Patterns of oviposition stimulants for carrot fly in leaves of various host plants . Journal of chemical ecology, 1999, vol. 25, no. 1, p. 67-87. DOI
  4. BORGKARLSON, AK., VALTEROVA, I., NILSSON, LA. VOLATILE COMPOUNDS FROM FLOWERS OF 6 SPECIES IN THE FAMILY APIACEAE - BOUQUETS FOR DIFFERENT POLLINATORS . Phytochemistry, 1994, vol. 35, no. 1, p. 111-119.
  5. Abdulmanea, Khaled., Prokudina, Elena A., Lankova, Petra., Vanickova, Lucie., Koblovska, Radka., Zeleny, Vaclav., Lapcik, Oldrich. Immunochemical and HPLC identification of isoflavonoids in the Apiaceae family.. Biochemical systematics and ecology, 2012, vol. 45, p. 237-243.
  6. Prior, Rikke M., Lundgaard, Nanna H., Light, Mamie E., Stafford, Gary I., van Staden, Johannes., Jaeger, Anna K. The polyacetylene falcarindiol with COX-1 activity isolated from Aegopodium podagraria L. . Journal of ethnopharmacology, 2007, vol. 113, no. 1, p. 176-178. DOI
  7. Ojala, T., Vuorela, P., Kiviranta, J., Vuorela, H., Hiltunen, R. A bioassay using Artemia salina for detecting phototoxicity of plant coumarins . Planta medica, 1999, vol. 65, no. 8, p. 715-718. DOI
  8. Battelli, MG., Barbieri, L., Bolognesi, A., Buonamici, L., Valbonesi, P., Polito, L., VanDamme, EJM., Peumans, WJ., Stirpe, F. Ribosome-inactivating lectins with polynucleotide: Adenosine glycosidase activity. FEBS LETTERS, 1997, vol. 408, no. 3, p. 355-359. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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