Botanical species · safety record

Agrostemma githago

The EFSA Compendium of Botanicals holds 6 constituent measurements and 3 adverse-effect records for Agrostemma githago. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Agrostemma githago L.

6Constituent measurements

3Safety records

6Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Lectins	Seed	—	—	—	Resolve DOI
Saponins	Seed	Solvent extraction	3.26 Percent	Unspecified	Resolve DOI
Githagin	Seed	—	—	—	No resolvable identifier
Githagin	Seed	—	—	—	No resolvable identifier
Saponins	Seed	Powder	6.84 Percent	Unspecified	No resolvable identifier
Saponins	Seed	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Hemopoietic	Cardiovascular / haematological	Seed	Powder	Gallus gallus (chicken) (as animal)	Other	No resolvable identifier
Hemopoietic	Cardiovascular / haematological	Seed	Powder	Gallus gallus (chicken) (as animal)	Chronic/long term toxicity	No resolvable identifier
Hemopoietic	Cardiovascular / haematological	Seed	Powder	Gallus gallus (chicken) (as animal)	Chronic/long term toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Ratsimamanga, Buu-Hoi, A. R., Janicaud, J. Some physiological properties of githagin.. Comptes rendus des seances de la societe de biologie et de ses filiales, 1944, vol. 138, p. 486-8.
Kotz, J. Morphology and pathogenesis of corn cockle (Agrostemma githago) poisoning in poultry. II. Own investigations.. Medycyna weterynaryjna, 1965, vol. 21, p. 143-50.
Poisonous substances obtained from seed oil of corn cockle.. Zzz, 1956, vol. 6, p. 285-93.
Melzig, MF., Hebestreit, P., Gaidi, G., Lacaille-Dubois, MA. Structure-activity-relationship of saponins to enhance toxic effects of agrostin . Planta medica, 2005, vol. 71, no. 11, p. 1088-1090. DOI
Hebestreit, P., Melzig, MF. Cytotoxic activity of the seeds from Agrostemma githago var. githago. Planta medica, 2003, vol. 69, no. 10, p. 921-925.
Brandl, J. Ueber Sapotoxin und Sapogenin von Agrostemma Githago. Archiv f�r experimentelle pathologie und pharmakologie, 1906, vol. 54, no. 4-5, p. 245-284. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature