Botanical species · safety record

Albizia julibrissin

The EFSA Compendium of Botanicals holds 8 constituent measurements and 4 adverse-effect records for Albizia julibrissin. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Albizia julibrissin Durazz.

8Constituent measurements

4Safety records

6Cited sources

138Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 138 licensed products naming Albizia julibrissin as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Extract Type TBA
Fresh
decoction

Source material stated

Bark
Cortex
Dried stems with bark
Flower
New material
Stem bark
Twig Bark

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Daidzein	Bark	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Saponins	Bark	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Syringaresinol	Bark	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Triterpene saponins	Bark	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Formononetin	Flower	Solvent extraction	—	—	No resolvable identifier
Gallic acid	Flower	Solvent extraction	—	—	No resolvable identifier
Lariciresinol	Flower	Solvent extraction	—	—	No resolvable identifier
Scopoletin	Flower	Solvent extraction	—	—	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Hepatotoxicity	Liver	Bark	Solvent extraction	House mouse (as animal)	Reproduction toxicity	Resolve DOI
Reproductive	Uterus	Bark	Solvent extraction	House mouse (as animal)	Reproduction toxicity	Resolve DOI
Nephrotoxicity	Urogenital: kidneys	—	—	House mouse (as animal)	Short-term toxicity	No resolvable identifier
Pulmonary and cardiac	Lung	Bark	—	House mouse (as animal)	Short-term toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Jung, MJ., Kang, SS., Jung, HA., Kim, GJ., Choi, JS. Isolation of flavonoids and a cerebroside from the stem bark of Aibizzia julibrissin . Archives of pharmacal research, 2004, vol. 27, no. 6, p. 593-599. DOI
Rong, Guang-Qing., Geng, Chang-An., Ma, Yun-Bao., Huang, Xiao-Yan., Wang, Hong-Ling., Zhao, Yong., Zhang, Xue-Mei., Chen, Ji-Jun. Chemical constituents from ethyl acetate extract of flower of Albizia julibrissin . . Zhongguo zhong yao za zhi = zhongguo zhongyao zazhi = china journal of chinese materia medica, 2014, vol. 39, no. 10, p. 1845-51.
Shu Yang., Cao Mei., Yin Zhong-Qiong., Li Ping., Li Tai-Qiang., Long Xing-Fa., Zhu Lian-Fa., Jia Ren-Yong., Dai Shu-Jun., Zhao Jian. The reproductive toxicity of saponins isolated from Cortex Albiziae in female mice . Chinese journal of natural medicines, 2015, vol. 13, no. 2, p. 119-126. DOI
Hua, Hui., Feng, Lei., Zhang, Xiao-ping., Zhang, Lian-fen., Jin, Jian. Anti-angiogenic activity of julibroside J(8), a natural product isolated from Albizia julibrissin . Phytomedicine, 2009, vol. 16, no. 8, p. 703-711. DOI
Kang, Xiaoxing., Gao, Yueying., Yu, Xingyun., Feng, Lei., Chen, Shuang., Qiu, Liying., Jin, Jian. Toxicity and mechanism of total saponin from bark of Albizia julibrissin on respiratory system in mice. Zhongyaocai, 2011, vol. 34, no. 3, p. 428-431.
Qiu, Liying., Li, Qian., Xu, Tianchan., Liu, Lingyan., Feng, Lei., Jin, Jian., Wu, Pengxi. Study of nephrotoxicity and its mechanism of saponin from Albizia julibrissin durazz in mice. Dulixue zazhi, 2011, vol. 25, no. 6, p. 431-434.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

Continue

Independent literature