Botanical species · safety record

Aloe arborescens

The EFSA Compendium of Botanicals holds 14 constituent measurements and 4 adverse-effect records for Aloe arborescens. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Aloe arborescens Mill.

14Constituent measurements

4Safety records

4Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Aloe-emodin	Leaves	Solvent extraction	0.51 Milligram/millilitre	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Aloe-emodin	Leaves	Solvent extraction	5.69 Microgram/gram	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	Resolve DOI
Aloenin	Leaves	Solvent extraction	312.34 Microgram/gram	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	Resolve DOI
Aloenin	Leaves	Solvent extraction	11.65 Milligram/millilitre	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Aloenin	Leaves	Solvent extraction	1.91 Percent	Unspecified	Resolve DOI
Aloin a	Leaves	Solvent extraction	0.83 Percent	Unspecified	Resolve DOI
Aloin a	Leaves	Solvent extraction	71.15 Microgram/gram	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	Resolve DOI
Aloin a	Leaves	Solvent extraction	11.37 Milligram/millilitre	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Aloin b	Leaves	Solvent extraction	80.96 Microgram/gram	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	Resolve DOI
Aloin b	Leaves	Solvent extraction	9.05 Milligram/millilitre	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Anthraquinones	Leaves	Solvent extraction	≤ 2.17 Percent	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Anthraquinones	Leaves	Solvent extraction	≥ 1.1 Percent	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Esculetin	Leaves	Solvent extraction	21.22 Microgram/gram	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	Resolve DOI
Umbelliferone	Leaves	Solvent extraction	10.61 Microgram/gram	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	Resolve DOI

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Digestive	Leaves	Powder	Rat (as animal)	Chronic/long term toxicity	Resolve DOI
Hemopoietic	Cardiovascular / haematological: lymph nodes	Leaves	Powder	Rat (as animal)	Chronic/long term toxicity	Resolve DOI
Hemopoietic	Cardiovascular / haematological	Leaves	Powder	Rat (as animal)	Chronic/long term toxicity	Resolve DOI
Nephrotoxicity	Urogenital: kidneys	Leaves	Powder	Rat (as animal)	Chronic/long term toxicity	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Koshioka (N�e Nishimura), M., Koshioka, M., Takino, Y., Suzuki, M. Studies on the evaluation of aloe arborescens Mill. Var. Natalensis berger and aloe extract (JP IX). Pharmaceutical biology, 1982, vol. 20, no. 2, p. 53-59. DOI
Olennikov, D. N., Ibragimov, T. A., Chelombit'ko, V. A., Nazarova, A. V., Rokhin, A. V., Zilfikarov, I. N. Chemical composition of Aloe arborescens and its change by biostimulation . Chemistry of natural compounds, 2009, vol. 45, no. 4, p. 478-482. DOI
Shimpo, K., Ida, C., Chihara, T., Beppu, H., Kaneko, T., Kuzuya, H. Aloe arborescens extract inhibits TPA-induced ear oedema, putrescine increase and tumour promotion in mouse skin . Phytotherapy research, 2002, vol. 16, no. 5, p. 491-493. DOI
Matsuda, Yoko., Yokohira, Masanao., Suzuki, Satoshi., Hosokawa, Kyoko., Yamakawa, Keiko., Zeng, Yu., Ninomiya, Fumiko., Saoo, Kousuke., Kuno, Toshiya., Imaida, Katsumi. One-year chronic toxicity study of Aloe arborescens Miller var. natalensis Berger in Wistar Hannover rats. A pilot study . Food and chemical toxicology, 2008, vol. 46, no. 2, p. 733-739. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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