Botanical species · safety record
Alstonia constricta
The EFSA Compendium of Botanicals holds 5 constituent measurements for Alstonia constricta. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Alstonia constricta Muell.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 2 licensed products naming Alstonia constricta as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Source material stated
What the records describe
Constituents measured
- Reserpine2
- Alkaloids1
- Alstonine1
- Vincamajine1
Plant parts
- Roots and other underground parts3
- Bark1
- Stem1
- stalk1
Preparations
- Solvent extraction5
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Alkaloids | Stem / stalk | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Alstonine | Bark | Solvent extraction | — | Unspecified | Resolve DOI |
| Reserpine | Roots and other underground parts | Solvent extraction | ≤ 0.28 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
| Reserpine | Roots and other underground parts | Solvent extraction | ≥ 0.23 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
| Vincamajine | Roots and other underground parts | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- CROW, WD., HANCOX, NC., JOHNS, SR., LAMBERTO.JA. NEW ALKALOIDS OF ALSTONIA-CONSTRICTA. AUSTRALIAN JOURNAL OF CHEMISTRY, 1970, vol. 23, no. 12, p. 2489-&.
- Crow, W. D., Greet, Yolande M. The occurrence of reserpine in Alstonia constricta.. Australian Journal of Chemistry, 1955, vol. 8, p. 460-3.
- ALLAM, K., BEUTLER, JA., LEQUESNE, PW. 14-KETOALSTONIDINE AND OTHER ALKALOIDAL CONSTITUENTS OF THE STEM BARK OF ALSTONIA-CONSTRICTA . Journal of natural products, 1987, vol. 50, no. 4, p. 623-625. DOI
- Leonard, Nelson J., Elderfield, Robert C. Alstonia alkaloids. I. Degradation of alstonine to beta-carboline bases and the reduction of tetrahydroalstonine with sodium and butyl alcohol.. Journal of Organic Chemistry, 1942, vol. 7, p. 556-72. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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