Botanical species · safety record

Alstonia scholaris

The EFSA Compendium of Botanicals holds 2 constituent measurements and 2 adverse-effect records for Alstonia scholaris. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Alstonia scholaris (L.) R.Br.

2Constituent measurements
2Safety records
3Cited sources
7Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 7 licensed products naming Alstonia scholaris as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

  • Dry

Source material stated

  • Bark

What the records describe

Constituents measured

  • Indole alkaloids1
  • Methyl salicylate1

Plant parts

  • Leaves3
  • Flower1

Preparations

  • Solvent extraction4

Effect types

  • Digestive2

Target tissues

  • Digestive2

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
Indole alkaloidsLeavesSolvent extractionHPLC with standard detection methodsResolve DOI
Methyl salicylateFlowerSolvent extraction1.1 Percent AreaGC-MSNo resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
DigestiveDigestiveLeavesSolvent extractionIn vitroResolve DOI
DigestiveDigestiveLeavesSolvent extractionIn vitroResolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Jong-Anurakkun, Nilubon., Bhandari, Megh Raj., Kawabata, Jun. alpha-Glucosidase inhibitors from Devil tree (Alstonia scholaris). FOOD CHEMISTRY, 2007, vol. 103, no. 4, p. 1319-1323. DOI
  2. Dung, NX., Ngoc, PH., Rang, DD., Nhan, NT., Klinkby, N., Ledercq, P. Chemical composition of the volatile concentrate from the flowers of Vietnamese Alstonia scholaris (L.) R.Br, Apocynaceae. JOURNAL OF ESSENTIAL OIL RESEARCH, 2001, vol. 13, no. 6, p. 424-426.
  3. Feng, Liang., Chen, Yan., Yuan, Ling., Liu, Xuan., Gu, Jun-Fei., Zhang, Ming-Hua., Wang, Ying. A Combination of Alkaloids and Triterpenes of Alstonia scholaris (Linn.) R. Br. Leaves Enhances Immunomodulatory Activity in C57BL/6 Mice and Induces Apoptosis in the A549 Cell Line. MOLECULES, 2013, vol. 18, no. 11, p. 13920-13939. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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