Botanical species · safety record

Ammi visnaga

The EFSA Compendium of Botanicals holds 18 constituent measurements and 1 adverse-effect record for Ammi visnaga. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Ammi visnaga (L.) Lam.

18Constituent measurements

1Safety records

7Cited sources

21Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 21 licensed products naming Ammi visnaga as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

Dried ripe fruit
Fruit
Fruit(s)
Ripe fruit(s)
Seed(s)

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Coumarins	Fruit unspecified	Solvent extraction	≤ 1.84 Percent	Chromatographic tests	Resolve DOI
Coumarins	Fruit unspecified	Solvent extraction	≥ 1.11 Percent	Chromatographic tests	Resolve DOI
Khellin	Fruit unspecified	Solvent extraction	≥ 0.75 Percent	Chromatographic tests	Resolve DOI
Khellin	Seed	Solvent extraction	361.9 Milligram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Khellin	Fruit unspecified	Solvent extraction	≤ 3.03 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Khellin	Fruit unspecified	Solvent extraction	≥ 2.27 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Khellin	Fruit unspecified	Solvent extraction	1 Microgram/millilitre	Chromatographic tests	Resolve DOI
Khellin	Fruit unspecified	Solvent extraction	≤ 1.01 Percent	Chromatographic tests	Resolve DOI
Visnagine	Seed	Solvent extraction	235.7 Milligram/gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Visnagine	Fruit unspecified	Solvent extraction	≤ 1.28 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Visnagine	Fruit unspecified	Solvent extraction	≥ 0.93 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Visnagine	Fruit unspecified	Solvent extraction	≤ 0.46 Percent	Chromatographic tests	Resolve DOI
Visnagine	Fruit unspecified	Solvent extraction	≥ 0.18 Percent	Chromatographic tests	Resolve DOI
Coumarins	Flowering top	—	—	Element spectroscopy	No resolvable identifier
Daidzein	Seed	Solvent extraction	62.4 Milligram/kilogram	UHPLC-MS-MS	No resolvable identifier
Formononetin	Seed	Solvent extraction	6.2 Milligram/kilogram	UHPLC-MS-MS	No resolvable identifier
Genistein	Seed	Solvent extraction	23 Milligram/kilogram	UHPLC-MS-MS	No resolvable identifier
Marmesin	Flowering top	—	—	Element spectroscopy	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Hepatotoxicity	Digestive	Seed	—	Gallus gallus (chicken) (as animal)	Subchronic	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Ibrahim, IA., ElBadwi, SMA., Gadir, WSA., Bakhiet, AO., Yagoub, SO., Adam, SEI. Susceptibility of Bovans chicks to low dietary levels of Ammi visnaga and Artemisia herba-alba . Veterinary and human toxicology, 2004, vol. 46, no. 2, p. 67-69.
Abdulmanea, Khaled., Prokudina, Elena A., Lankova, Petra., Vanickova, Lucie., Koblovska, Radka., Zeleny, Vaclav., Lapcik, Oldrich. Immunochemical and HPLC identification of isoflavonoids in the Apiaceae family.. Biochemical systematics and ecology, 2012, vol. 45, p. 237-243.
Baddar, F.G., Farid, S., Starkovsky, N.A. The coumarins of ammi visnaga L. Part I. Their reactions with benzene, toluene, and anisole in presence of aluminium chloride: Isolation of minor constituents of ammi visnaga. Journal of the chemical society (resumed), 1963, p. 4598-4600.
Winderl, Bianca., Schwaiger, Stefan., Ganzera, Markus. Fast and improved separation of major coumarins in Ammi visnaga (L.) Lam. by supercritical fluid chromatography . Journal of separation science, 2016, vol. 39, no. 20, p. 4042-4048. DOI
Pavela, Roman., Vrchotova, Nadezda., Triska, Jan. Larvicidal activity of extracts from Ammi visnaga Linn. (Apiaceae) seeds against Culex quinquefasciatus Say. (Diptera: Culicidae) . Experimental parasitology, 2016, vol. 165, p. 51-57. DOI
Zgorka, G., Dragan, T., Glowniak, K., Basiura, E. Determination of furanochromones and pyranocoumarins in drugs and Ammi visnaga fruits by combined solid-phase extraction-high-performance liquid chromatography and thin-layer chromatography-high-performance liquid chromatography . Journal of chromatography a, 1998, vol. 797, no. 1-2, p. 305-309. DOI
Schimmer, O., Rauch, P. Inhibition of metabolic activation of the promutagens, benzo a pyrene, 2-aminofluorene and 2-aminoanthracene by furanochromones in Salmonella typhimurium . Mutagenesis, 1998, vol. 13, no. 4, p. 385-389. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature