Botanical species · safety record

Anadenanthera colubrina

The EFSA Compendium of Botanicals holds 11 constituent measurements and 2 adverse-effect records for Anadenanthera colubrina. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Anadenanthera colubrina (Vell.) Brenan

11Constituent measurements

2Safety records

7Cited sources

0Licensed products (Canada)

Also recorded as

Anadenanthera colubrina var. colubrina

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Tannins	Aerial part of plants	Solvent extraction	≥ 3 Percent	Classification not possible	Resolve DOI
Tannins	Aerial part of plants	Solvent extraction	≤ 10 Percent	Classification not possible	Resolve DOI
Tannins	Bark	Solvent extraction	—	Traditional analytical techniques (wet chemical tests)	Resolve DOI
Tannins	Leaves	Solvent extraction	—	Traditional analytical techniques (wet chemical tests)	Resolve DOI
Bufotenine	Seed	Solvent extraction	2 Percent	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Bufotenine	Seed	—	0.5 Percent	Colorimetry, Spectroscopy (Spectrometry) and Photometry	No resolvable identifier
Bufotenine	Seed	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Hydrocyanic acid	Leaves	Fresh	—	Phytochemical screening	No resolvable identifier
Tannins	Bark	Solvent extraction	≥ 18 Percent	—	No resolvable identifier
Tannins	Bark	—	15.4 Percent	Traditional analytical techniques (wet chemical tests)	No resolvable identifier
Tannins	Bark	Solvent extraction	≤ 35 Percent	—	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Neurotoxicity	Neurologic: central nervous system	Seed	Solvent extraction	Human (as organism)	Study with volunteers	No resolvable identifier
Systemic	Respiratory	Leaves	—	Cattle (as animal)	Acute toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Monteiro, J�lio M., Albuquerque, Ulysses P., Lins Neto, Ernani M.F., Ara�jo, Elcida L., Albuquerque, Miracy M., Amorim, Elba L.C. The effects of seasonal climate changes in the caatinga on tannin levels in Myracrodruon urundeuva (Engl.) Fr. All. and Anadenanthera colubrina (Vell.) Brenan . Revista brasileira de farmacognosia, 2006, vol. 16, no. 3, p. 338-344. DOI
Vigerelli Hugo., Sciani Juliana Mozer., Pimenta Daniel C., Jared Carlos., Antoniazzi Marta Maria., Caporale Graciane Maria Medeiros., da Silva Andrea de Cassia Rodrigues. Bufotenine is able to block rabies virus infection in BHK-21 cells. The journal of venomous animals and toxins including tropical diseases, 2014, vol. 20, no. 1, p. 45.
Rendon P., Willy J. Isolation of bufotenine from seeds of the Piptadenia macrocarpa Benth.. Revista boliviana de quimica, 1985, vol. 5, no. 1, p. 39-43.
Ott, J. Pharmanopo-psychonautics: Human intranasal, sublingual, intrarectal, pulmonary and oral pharmacology of bufotenine . Journal of psychoactive drugs, 2001, vol. 33, no. 3, p. 273-281.
Tokarnia, Carlos Hubinger., Peixoto, Paulo Vargas., Dobereiner, Jurgen. Experimental poisoning by Piptadenia macrocarpa (Leg. Mimosoideae) in bovines . Pesquisa veterinaria brasileira, 1994, vol. 14, no. 2-3, p. 57-63.
Paes, Juarez Benigno., Franco Diniz, Carlos Estevam., de Lima, Carlos Roberto., Bastos, Paulo de Melo., de Medeiros Neto, Pedro Nico. CONDENSED TANNINS OF Anadenanthera colubrina VAR. cebil BARK EXTRACTED WITH SODIUM HYDROXIDE AND SODIUM SULFITE SOLUTIONS . Revista caatinga, 2013, vol. 26, no. 3, p. 22-27.
Prado, Luis L., Ricci, Enzo. Systematic study of the tannin content of various indigenous species.. Zzz, 1956, p. 7-17.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature