Angelica archangelica

Also recorded as

• Archangelica officinalis Hoffm.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 190 licensed products naming Angelica archangelica as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

What the records describe

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

40 of 51 records are shown, ordered so that records carrying a resolvable reference come first.

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

1. Muller, Melanie., Byres, Maureen., Jaspars, Marcel., Kumarasamy, Yashodharan., Middleton, Moira., Nahar, Lutfun., Shoeb, Mohammad., Sarker, Satyajit D. 2D NMR spectroscopic analyses of archangelicin from the seeds of Angelica archangelica . Acta pharmaceutica (zagreb), 2004, vol. 54, no. 4, p. 277-285.
2. Pavela, Roman., Zabka, Martin., Vrchotova, Nadezda., Triska, Jan., Kazda, Jan. Selective effects of the extract from Angelica archangelica L. against Harmonia axyridis (Pallas)-An important predator of aphids . Industrial crops and products, 2013, vol. 51, p. 87-92. DOI
3. Oniszczuk, Anna., Skalicka-Wozniak, Krystyna., Oniszczuk, Tomasz., Waksmundzka-Hajnos, Monika., Glowniak, Kaziemirz. Matrix Solid-Phase Dispersion versus Ultrasound Assisted Extraction with Solid-Phase Extraction in the HPLC Analysis of Furanocoumarins from Fruits of Archangelica officinalis Hoffm. . Journal of the brazilian chemical society, 2014, vol. 25, no. 7, p. 1166-1171. DOI
4. Sigurdsson, Steinthor., Jonsdottir, Sigridur., Gudbjarnason, Sigmundur. Geographical Variation of the Furanocoumarin Composition of the Fruits of Icelandic Angelica archangelica . Zeitschrift fur naturforschung section c-a journal of biosciences, 2012, vol. 67, no. 1-2, p. 1-7.
5. Brown, Stewart A., Shyluk, J. P. Gas-liquid chromatography of some naturally occurring coumarins. Anal. chem., 1962, vol. 34, p. 1058-61.
6. Chatterjee, A., Sen Gupta, S. Constitution of archangelin, a new coumarin isolated from the root of Angelica archangelica. Tetrahedron letters, 1964, vol. (29-30), p. 1961-5.
7. Spath, E., Vierhapper, F. Natural coumarins. XL. Coumarins of the drug semen angelicae. Monatshefte fuer chemie, 1938, vol. 72, p. 179-89.
8. Raquet, Nicole., Schrenk, Dieter. Application of the equivalency factor concept to the phototoxicity and -genotoxicity of furocoumarin mixtures . Food and chemical toxicology, 2014, vol. 68, p. 257-266. DOI
9. Ojala, T., Vuorela, P., Kiviranta, J., Vuorela, H., Hiltunen, R. A bioassay using Artemia salina for detecting phototoxicity of plant coumarins . Planta medica, 1999, vol. 65, no. 8, p. 715-718. DOI
10. Svendsen, Anders Baerheim. Chemistry of Norwegian Umbelliferae. Johan grundt tanum forlag, oslo, 1954, p. 144 pp.
11. Chatterjee, Asima., Chakravarty, A., Mukherjee, Rabindranath. Chemistry of the seeds of Angelica archangelica. Journal of the indian chemical society, 1967, vol. 44, no. 2, p. 110-14.
12. Glowniak, Kazimierz., Gawron, Antoni., Kwietniewska, Barbara. Study of the coumarins of Archangelica officinalis Hoffm. fruit. Annales universitatis mariae curie-sklodowska, sectio d: medicina, 1976, vol. 31, p. 349-54.
13. Dranitsyna, Yu. A., Pigulevskii, G. V., Bukreeva, T. V. Coumarins from fruits of Angelica archangelica. Zhurnal prikladnoi khimii (sankt-peterburg, russian federation), 1965, vol. 38, no. 11, p. 2570-5.
14. Luszczki, Jarogniew J., Andres-Mach, Marta., Glensk, Michal., Skalicka-Wozniak, Krystyna. Anticonvulsant effects of four linear furanocoumarins, bergapten, imperatorin, oxypeucedanin, and xanthotoxin, in the mouse maximal electroshock-induced seizure model: a comparative study. PHARMACOLOGICAL REPORTS, 2010, vol. 62, no. 6, p. 1231-1236.

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