Botanical species · safety record

Angelica sylvestris

The EFSA Compendium of Botanicals holds 39 constituent measurements for Angelica sylvestris. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Angelica sylvestris L.

39Constituent measurements

0Safety records

12Cited sources

0Licensed products (Canada)

Also recorded as

Angelica sylvestris var. elatior Wahlenb.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Bergapten	Seed	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Furanocoumarins	Seed	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Furanocoumarins	Fruit unspecified	Solvent extraction	—	—	Resolve DOI
Furanocoumarins	Roots and other underground parts	Solvent extraction	—	—	Resolve DOI
Imperatorin	Seed	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Isoimperatorin	Seed	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Umbelliprenin	Seed	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Archangelicin	Roots and other underground parts	Solvent extraction	0.285 Milligram/gram	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Bergapten	Fruit unspecified	Solvent extraction	1.807 Milligram/gram	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Bergaptol	Roots and other underground parts	Solvent extraction	—	—	No resolvable identifier
Biochanin-a	Leaves	Solvent extraction	1.8 Milligram/kilogram	Mass Spectroscopy and hyphenated methods without chromatography	No resolvable identifier
Bisabolangelone	Fruit unspecified	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Bisabolangelone	Seed	—	—	Unspecified	No resolvable identifier
Coumarins	Flower	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Coumarins	Fruit unspecified	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Coumarins	Aerial part of plants	Solvent extraction	≥ 1.2 Percent	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Coumarins	Aerial part of plants	Solvent extraction	≤ 2.5 Percent	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Daidzein	Leaves	Solvent extraction	3.6 Milligram/kilogram	Mass Spectroscopy and hyphenated methods without chromatography	No resolvable identifier
Formononetin	Leaves	Solvent extraction	12.4 Milligram/kilogram	Mass Spectroscopy and hyphenated methods without chromatography	No resolvable identifier
Furanocoumarins	Roots and other underground parts	Solvent extraction	1.75 Milligram/gram	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Furanocoumarins	Roots and other underground parts	Solvent extraction	—	—	No resolvable identifier
Genistein	Leaves	Solvent extraction	0.9 Milligram/kilogram	Mass Spectroscopy and hyphenated methods without chromatography	No resolvable identifier
Heraclenin	Fruit unspecified	Solvent extraction	3 Milligram/gram	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Heraclenin	Fruit unspecified	Solvent extraction	0.38 Milligram/gram	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Imperatorin	Fruit unspecified	Solvent extraction	2.06 Milligram/gram	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Imperatorin	Fruit unspecified	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Isoformononetin	Leaves	Solvent extraction	0.4 Milligram/kilogram	Mass Spectroscopy and hyphenated methods without chromatography	No resolvable identifier
Isoimperatorin	Roots and other underground parts	Solvent extraction	0.59 Milligram/gram	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Isoimperatorin	Roots and other underground parts	Solvent extraction	—	—	No resolvable identifier
Isooxypeucedanin	Fruit unspecified	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Nodakenin	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Oxypeucedanin	Leaves	Solvent extraction	0.28 Milligram/gram	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Oxypeucedanin	Fruit unspecified	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Oxypeucedanin	Roots and other underground parts	—	—	UV/VIS spectroscopy (photometry)	No resolvable identifier
Oxypeucedanin	Roots and other underground parts	Solvent extraction	0.21 Milligram/gram	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Oxypeucedanin hydrate	Roots and other underground parts	Solvent extraction	—	—	No resolvable identifier
Umbelliferone	Fruit unspecified	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Umbelliferone	Roots and other underground parts	—	—	UV/VIS spectroscopy (photometry)	No resolvable identifier
Umbelliprenin	Fruit unspecified	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Hoerhammer, L., Wagner, H., Eyrich, W. Contents of the fruit of Angelica silvestris. Zeitschrift fuer naturforschung, 1963, vol. 18o, no. 8, p. 639-41.
Murphy, EM., Nahar, L., Byres, M., Shoeb, M., Siakalima, M., Rahman, MM., Gray, AI., Sarker, SD. Coumarins from the seeds of Angelica sylvestris (Apiaceae) and their distribution within the genus Angelica . Biochemical systematics and ecology, 2004, vol. 32, no. 2, p. 203-207. DOI
Milosavljevic, Slobodan., Jeremic, Dragoslav., Nevescanin, Marina., Radovanovic, Gorica., Zivanovic, Predrag., Todorovic, Branislava., Slavkovska, Violeta., Vajs, Vlatka. Furo- and pyranocoumarins from plant species Angelica silvestris and Peucedanum austriacum. Journal of the serbian chemical society, 1993, vol. 58, no. 12, p. 997-1001.
Caporale, Guiseppe., Rodighiero, Giovanni. Furocoumarins in the roots of Angelica sylvestris. Ricerca sci., rend., 1961, vol. Sec. B [2] 1, p. 127-30.
Abdulmanea, Khaled., Prokudina, Elena A., Lankova, Petra., Vanickova, Lucie., Koblovska, Radka., Zeleny, Vaclav., Lapcik, Oldrich. Immunochemical and HPLC identification of isoflavonoids in the Apiaceae family.. Biochemical systematics and ecology, 2012, vol. 45, p. 237-243.
Kopecky, J., Toman, J., Saman, D., Bartova, L., Novotny, L., Harmatha, J. Substances contained in the rhizome of Angelica sylvestris L. Cesko-slovenska farmacie, 1989, vol. 38, no. 3, p. 130-2.
Ozipek, Meltem., Calis, Ihsan., Okuyama, Toru., Okada, Yoshihito. A dihydrofurocoumarin glucoside from Angelica sylvestris. Hacettepe universitesi eczacilik fakultesi dergisi, 1998, vol. 18, no. 1, p. 15-18.
Svendsen, Anders Baerheim. Chemistry of Norwegian Umbelliferae. Johan grundt tanum forlag, oslo, 1954, p. 144 pp.
Kopecky, J., Vokac, K., Toman, J., Novotny, L., Harmatha, J. Determination of bisabolangelone in fruits of Angelica sylvestris by HPLC. Prace naukowe instytutu chemii organicznej i fizycznej politechniki wroclawskiej, 1988, vol. 33, no. 8, p. 87-9.
NAWROT, J., BLOSZYK, E., HARMATHA, J., NOVOTNY, L. THE EFFECT OF BISABOLOANGELONE, HELENALIN AND BAKKENOLIDE-A ON DEVELOPMENT AND BEHAVIOR OF SOME STORED PRODUCT BEETLES . Zeitschrift fur angewandte entomologie-journal of applied entomology, 1984, vol. 98, no. 4, p. 394-398.
Carbonnier, Jacques., Molho, Darius. Change of coumarin contents of inflorescences of Angelica sylvestris L. Bulletin du museum national d'histoire naturelle, sciences physico-chimiques, 1978, vol. 19, p. 29-35.
CARBONNIER, J., MOLHO, D. FUROCOUMARINS IN ARCHANGELICA OFFICINALIS AND ANGELICA SILVESTRIS - DISTRIBUTION OF 5-BETA-CYCLOLAVANDULYLOXY-PSORALEN IN THE GENUS ANGELICA . Planta medica, 1982, vol. 44, no. 3, p. 162-165. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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