Botanical species · safety record
Angostura trifoliata
The EFSA Compendium of Botanicals holds 18 constituent measurements for Angostura trifoliata. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Angostura trifoliata (Willd.) T.S.Elias
Also recorded as
Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Quinoline alkaloids7
- Cuspareine3
- Galipine3
- Galipinine2
- Candicine1
- Galipeine1
- Maculosidine1
Plant parts
- Bark18
Preparations
- Solvent extraction18
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Candicine | Bark | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Cuspareine | Bark | Solvent extraction | — | GC-MS | Resolve DOI |
| Cuspareine | Bark | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Galipeine | Bark | Solvent extraction | — | GC-MS | Resolve DOI |
| Galipine | Bark | Solvent extraction | — | GC-MS | Resolve DOI |
| Galipine | Bark | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Galipinine | Bark | Solvent extraction | — | GC-MS | Resolve DOI |
| Galipinine | Bark | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Maculosidine | Bark | Solvent extraction | — | GC-MS | Resolve DOI |
| Quinoline alkaloids | Bark | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Quinoline alkaloids | Bark | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Quinoline alkaloids | Bark | Solvent extraction | — | GC-MS | Resolve DOI |
| Quinoline alkaloids | Bark | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Cuspareine | Bark | Solvent extraction | — | Physical tests | No resolvable identifier |
| Galipine | Bark | Solvent extraction | — | Physical tests | No resolvable identifier |
| Quinoline alkaloids | Bark | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
| Quinoline alkaloids | Bark | Solvent extraction | — | Physical tests | No resolvable identifier |
| Quinoline alkaloids | Bark | Solvent extraction | — | — | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Beckurts, Heinrich. Angostura alkaloids. Archiv der pharmazie (weinheim, germany), 1895, vol. 233, p. 410-23.
- Jacquemond-Collet, I., Bessiere, JM., Hannedouche, S., Bertrand, C., Fouraste, I., Moulis, C. Identification of the alkaloids of Galipea officinalis by gas chromatography-mass spectrometry . Phytochemical analysis, 2001, vol. 12, no. 5, p. 312-319. DOI
- Rakotoson, JH., Fabre, N., Jacquemond-Collet, I., Hannedouche, S., Fouraste, I., Moulis, C. Alkaloids from Galipea officinalis. Planta medica, 1998, vol. 64, no. 8, p. 762-763. DOI
- Jacquemond-Collet, I., Hannedouche, S., Fouraste, I., Moulis, C. Novel quinoline alkaloid from trunk bark of Galipea officinalis. Fitoterapia, 2000, vol. 71, no. 5, p. 605-606. DOI
- Houghton, P. J., Watabe, Yukiko., Woldemariam, T. Z., Yates, M. Activity of alkaloids from Angostura bark against Mycobacterium tuberculosis . Journal of pharmacy and pharmacology, 1998, vol. 50, no. SUPPL., p. 230-230.
- Houghton, PJ., Woldemariam, TZ., Watanabe, Y., Yates, W. Activity against Mycobacterium tuberculosis of alkaloid constituents of Angostura bark, Galipea officinalis . Planta medica, 1999, vol. 65, no. 3, p. 250-254. DOI
- Brieskorn, Carl H., Beck, Volker. Another alkaloid from angostura bark. Praeparative pharmazie, 1970, vol. 6(11-12), p. 177-81.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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