Botanical species · safety record

Antiaris toxicaria

The EFSA Compendium of Botanicals holds 14 constituent measurements for Antiaris toxicaria. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Antiaris toxicaria Lesch.

14Constituent measurements

0Safety records

10Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Antiarins	Bark	Solvent extraction	—	Unspecified	Resolve DOI
Cardenolides	Bark	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Cardenolides	Stem / stalk	Solvent extraction	—	HPLC with standard detection methods	Resolve DOI
Cardenolides	Bark	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Cardenolides	Unspecified	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Cardenolides	Seed	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Cardiac glycosides	Bark	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Furanocoumarins	Stem / stalk	Solvent extraction	—	UV/VIS spectroscopy (photometry)	Resolve DOI
Lignans	Stem / stalk	Solvent extraction	—	UV/VIS spectroscopy (photometry)	Resolve DOI
Neolignans	Stem / stalk	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Periplogenin	Seed	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Pranferol	Bark	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Strophantidin	Stem / stalk	Solvent extraction	—	HPLC with standard detection methods	Resolve DOI
Convallatoxin	Seed	Solvent extraction	0.325 Percent	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Li, Xiao-San., Zhu, Jing-Jing., Zhao, Huan., Li, Shun-Lin., Hao, Xiao-Jiang., Yao, Xin-Sheng., Tang, Jin-Shan. Three new compounds from the bark of Antiaris toxicaria. Phytochemistry letters, 2015, vol. 13, p. 182-186. DOI
Wu, Xiu-Li., Wu, Yu-Ling., Li, Hou-Gang., Liu, He-Tao., Fu, Xue-Yan., Cui, Rui-Qin., Wang, Jian-Huan., Liu, Cheng., Chen, Jing. A new periplogenin cardenolide from the seeds of Antiaris toxicaria. Journal of asian natural products research, 2014, vol. 16, no. 4, p. 418-421. DOI
Carter, CA., Forney, RW., Gray, EA., Gehring, AM., Schneider, TL., Young, DB., Lovett, CM., Scott, L., Messer, AC., Richardson, DP. Toxicarioside A. A new cardenolide isolated from Antiaris toxicaria latex-derived dart poison. Assignment of the H-1- and C-13-NMR shifts for an antiarigenin aglycone. . Tetrahedron, 1997, vol. 53, no. 40, p. 13557-13566. DOI
Jiang, Miao-Miao., Gao, Hao., Dai, Yi., Zhang, Xue., Wang, Nai-Li., Yao, Xin-Sheng. Phenylpropanoid and Lignan Derivatives from Antiaris toxicaria and their Effects on Proliferation and Differentiation of an Osteoblast-Like Cell Line . Planta medica, 2009, vol. 75, no. 4, p. 340-345. DOI
Jiang, Miao-Miao., Dai, Yi., Gao, Hao., Zhang, Xue., Wang, Guang-Hui., He, Jia-You., Hu, Qiong-Ying., Zeng, Jin-Zhang., Zhang, Xiao-Kun., Yao, Xin-Sheng. Cardenolides from Antiaris toxicaria as potent selective Nur77 modulators . Chemical & pharmaceutical bulletin, 2008, vol. 56, no. 7, p. 1005-1008. DOI
Carter, CA., Gray, EA., Schneider, TL., Lovett, CM., Scott, L., Messer, AC., Richardson, DP. Toxicarioside B and toxicarioside C. New cardenolides isolated from Antiaris toxicaria latex-derived dart poison . Tetrahedron, 1997, vol. 53, no. 50, p. 16959-16968. DOI
Shi, Li-Shian., Liao, Yu-Ren., Su, Ming-Jai., Lee, An-Sheng., Kuo, Ping-Chung., Damu, Amooru G., Kuo, Sheng-Chu., Sun, Han-Dong., Lee, Kuo-Hsiung., Wu, Tian-Shung. Cardiac Glycosides from Antiaris toxicaria with Potent Cardiotonic Activity . Journal of natural products, 2010, vol. 73, no. 7, p. 1214-1222. DOI
Agrawal, Poonam., Akhade, Meenakshi., Laddha, Kirti., Narkhede, Satish., Mirgal, Amit., Salunke, Chandrakant. Quantification of Convallatoxin in Antiaris toxicaria Leusch seeds by RP-HPLC. Analytical chemistry letters, 2014, vol. 4, no. 3, p. 172-177.
KOPP, B., BAUER, WP., BERNKOPSCHNURCH, A. ANALYSIS OF SOME MALAYSIAN DART POISONS. Journal of ethnopharmacology, 1992, vol. 36, no. 1, p. 57-62. DOI
Seligmann, C.G. Report LXXV: On the physiological action of the Kenyah dart poison and its active principle antiarin. British medical journal, 1903, vol. 1, no. 2211, p. 1129-1131. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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