Botanical species · safety record

Arctium lappa

The EFSA Compendium of Botanicals holds 3 constituent measurements and 3 adverse-effect records for Arctium lappa. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Arctium lappa L.

3Constituent measurements

3Safety records

4Cited sources

1,133Licensed products (Canada)

Also recorded as

Arctium majus (Gaertn.) Bernh.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 1,133 licensed products naming Arctium lappa as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Extract Type TBA
Fresh
fluid
solid

Source material stated

Aged bark
Arctium lappa - root
Arctium lappa - fruit
Arctium lappa- root and rhizome
Bark and buds
Burdock Root Extract
Dried ripe fruit
Dried root(s)

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Arctigenin	Live plants	Solvent extraction	—	Unspecified	Resolve DOI
Arctiin	Fruit unspecified	—	—	Unspecified	Resolve DOI
Atropine	Roots and other underground parts	Solvent extraction	0.76 Milligram/gram	Gaschromatography (GC)	Resolve DOI

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Neurotoxicity	Neurologic: central nervous system	Roots and other underground parts	Solvent extraction	Human (as organism)	Case report	Resolve DOI
Reproductive	Uterus	Roots and other underground parts	Solvent extraction	Human (as organism)	Reproduction toxicity	No resolvable identifier
Reproductive	Uterus	Leaves	Solvent extraction	Human (as organism)	Reproduction toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Rhoads, P.M., Tong, T.G., Banner, W., Anderson, R. Anticholinergic poisonings associated with commercial burdock root tea. Clinical toxicology, 1984, vol. 22, no. 6, p. 581-584. DOI
Shah, Ghulam Mujtaba., Khan, Mir Ajab., Ahmad, Mushtaq., Zafar, Muhammad., Khan, Aftab Ahmed. Observations on antifertility and abortifacient herbal drugs. African journal of biotechnology, 2009, vol. 8, no. 9, p. 1959-1964.
Susanti, Siti., Iwasaki, Hironori., Itokazu, Yukiyoshi., Nago, Mariko., Taira, Naoyuki., Saitoh, Seikoh., Oku, Hirosuke. Tumor specific cytotoxicity of arctigenin isolated from herbal plant Arctium lappa L. . Journal of natural medicines, 2012, vol. 66, no. 4, p. 614-621. DOI
Wu, Jian-Guo., Wu, Jin-Zhong., Sun, Lian-Na., Han, Ting., Du, Jian., Ye, Qi., Zhang, Hong., Zhang, Yu-Guang. Ameliorative effects of arctiin from Arctium lappa on experimental glomerulonephritis in rats . Phytomedicine, 2009, vol. 16, no. 11, p. 1033-1041. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature