Botanical species · safety record
Arctium minus
The EFSA Compendium of Botanicals holds 4 constituent measurements, 1 adverse-effect record and 1 genotoxicity assay for Arctium minus. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Arctium minus (Hill) Bernh.
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Sesquiterpene lactones2
- Atropine1
- Calcium oxalate1
Plant parts
- Roots and other underground parts2
- Aerial part of plants1
- Leaves1
- Unspecified1
Preparations
- Solvent extraction5
Effect types
- Neurotoxicity1
Target tissues
- Neurologic1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Atropine | Roots and other underground parts | Solvent extraction | 300 Milligram/gram | GC-MS | Resolve DOI |
| Calcium oxalate | Aerial part of plants | Solvent extraction | — | Microscopic detection | Resolve DOI |
| Sesquiterpene lactones | Unspecified | Solvent extraction | — | Unspecified | No resolvable identifier |
| Sesquiterpene lactones | Leaves | Solvent extraction | — | — | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Neurotoxicity | Neurologic | Roots and other underground parts | Solvent extraction | Human (as organism) | Case report | Resolve DOI |
Genotoxicity testing
Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.
| Outcome | Endpoint | Test | Tested organism | Metabolic activation | Source |
|---|---|---|---|---|---|
| Inconclusive | DNA damage and/or repair | single cell gel/comet assay in mammalian cells for detection of DNA damage | Human (as organism) | Not applicable | Resolve DOI |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Basaran, AA., Yu, TW., Plewa, MJ., Anderson, D. An investigation of some turkish herbal medicines in Salmonella typhimurium and in the COMET assay in human lymphocytes. TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS, 1996, vol. 16, no. 2, p. 125-138. DOI
- Suchy, M., Horak, M., Herout, V., Sorm, F. Terpenes. LXXXIV. The structure of arctiopicrin, sesquiterpene lactone from Arctium minus Bernh. Croatica chemica acta, 1957, vol. 29, p. 247-54.
- Plourde, J. R., Mockle, J. A. Phytochemical investigations on Compositae. III. Arctium minus. Preliminary investigations with particular reference to a lactone principle. Canadian pharmaceutical journal, 1961, vol. 94(No. 1), p. 33-5.
- BRYSON, PD., WATANABE, AS., RUMACK, BH., MURPHY, RC. BURDOCK ROOT TEA POISONING - CASE-REPORT INVOLVING A COMMERCIAL PREPARATION . Jama-journal of the american medical association, 1978, vol. 239, no. 20, p. 2157-2157. DOI
- Kartal, Ciler. CALCIUM OXALATE CRYSTALS IN SOME SPECIES OF THE TRIBE CARDUEAE (ASTERACEAE) . Botanical sciences, 2016, vol. 94, no. 1, p. 107-119. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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