Botanical species · safety record

Arctium minus

The EFSA Compendium of Botanicals holds 4 constituent measurements, 1 adverse-effect record and 1 genotoxicity assay for Arctium minus. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Arctium minus (Hill) Bernh.

4Constituent measurements
2Safety records
5Cited sources
0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Sesquiterpene lactones2
  • Atropine1
  • Calcium oxalate1

Plant parts

  • Roots and other underground parts2
  • Aerial part of plants1
  • Leaves1
  • Unspecified1

Preparations

  • Solvent extraction5

Effect types

  • Neurotoxicity1

Target tissues

  • Neurologic1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
AtropineRoots and other underground partsSolvent extraction300 Milligram/gramGC-MSResolve DOI
Calcium oxalateAerial part of plantsSolvent extractionMicroscopic detectionResolve DOI
Sesquiterpene lactonesUnspecifiedSolvent extractionUnspecifiedNo resolvable identifier
Sesquiterpene lactonesLeavesSolvent extractionNo resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
NeurotoxicityNeurologicRoots and other underground partsSolvent extractionHuman (as organism)Case reportResolve DOI

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

OutcomeEndpointTestTested organismMetabolic activationSource
InconclusiveDNA damage and/or repairsingle cell gel/comet assay in mammalian cells for detection of DNA damageHuman (as organism)Not applicableResolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Basaran, AA., Yu, TW., Plewa, MJ., Anderson, D. An investigation of some turkish herbal medicines in Salmonella typhimurium and in the COMET assay in human lymphocytes. TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS, 1996, vol. 16, no. 2, p. 125-138. DOI
  2. Suchy, M., Horak, M., Herout, V., Sorm, F. Terpenes. LXXXIV. The structure of arctiopicrin, sesquiterpene lactone from Arctium minus Bernh. Croatica chemica acta, 1957, vol. 29, p. 247-54.
  3. Plourde, J. R., Mockle, J. A. Phytochemical investigations on Compositae. III. Arctium minus. Preliminary investigations with particular reference to a lactone principle. Canadian pharmaceutical journal, 1961, vol. 94(No. 1), p. 33-5.
  4. BRYSON, PD., WATANABE, AS., RUMACK, BH., MURPHY, RC. BURDOCK ROOT TEA POISONING - CASE-REPORT INVOLVING A COMMERCIAL PREPARATION . Jama-journal of the american medical association, 1978, vol. 239, no. 20, p. 2157-2157. DOI
  5. Kartal, Ciler. CALCIUM OXALATE CRYSTALS IN SOME SPECIES OF THE TRIBE CARDUEAE (ASTERACEAE) . Botanical sciences, 2016, vol. 94, no. 1, p. 107-119. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

Continue