Botanical species · safety record

Arctostaphylos uva-ursi

The EFSA Compendium of Botanicals holds 17 constituent measurements and 1 adverse-effect record for Arctostaphylos uva-ursi. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Arctostaphylos uva-ursi (L.) Spreng.

17Constituent measurements

1Safety records

4Cited sources

446Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 446 licensed products naming Arctostaphylos uva-ursi as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Extract Type TBA
Fresh

Source material stated

Arctostaphylos uva-ursi - Leaf
Dried leaf
Dried leaves
Fresh leaves or fresh leaves and tips of young twigs
Fruit
Herb top
Herb(s)
Leaf

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Corilagin	Leaves	—	57.51 Microgram/gram	GC-MS	Resolve DOI
Corilagin	Roots and other underground parts	—	0.66 Microgram/gram	GC-MS	Resolve DOI
Corilagin	Stem / stalk	—	15.03 Microgram/gram	GC-MS	Resolve DOI
Epigallocatechin	Leaves	—	15.76 Microgram/gram	GC-MS	Resolve DOI
Epigallocatechin	Stem / stalk	—	9.19 Microgram/gram	GC-MS	Resolve DOI
Gallic acid	Roots and other underground parts	—	0.03 Microgram/gram	GC-MS	Resolve DOI
Gallic acid	Leaves	—	2.66 Microgram/gram	GC-MS	Resolve DOI
Gallic acid	Stem / stalk	—	0.89 Microgram/gram	GC-MS	Resolve DOI
Tannins	Leaves	—	72.58 Microgram/gram	GC-MS	Resolve DOI
Tannins	Stem / stalk	—	19.15 Microgram/gram	GC-MS	Resolve DOI
Tannins	Roots and other underground parts	—	0.66 Microgram/gram	GC-MS	Resolve DOI
Corilagin	Leaves	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Ellagitannins (hydrolysable tannins)	Leaves	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Gallic acid	Leaves	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Gallotannins	Leaves	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Tannins	Leaves	Solvent extraction	≤ 24.5 Percent	Unspecified	No resolvable identifier
Tannins	Leaves	Solvent extraction	≥ 10.1 Percent	Unspecified	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Other toxicities	—	—	—	Human (as organism)	Case report	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Olennikov, D. N., Chekhirova, G. V. 6 ''-Galloylpicein and other phenolic compounds from Arctostaphylos uva-ursi . Chemistry of natural compounds, 2013, vol. 49, no. 1, p. 1-7. DOI
Wang, L., Del Priore, L.V. Bull's-Eye maculopathy secondary to herbal toxicity from uva ursi. American journal of ophthalmology, 2004, vol. 137, no. 6, p. 1135-1137. DOI
Britton, G., Haslam, E. Gallotannins. XII. Phenolic constituents of Arctostaphylos uva-ursi. Journal of the chemical society, 1965, vol. (Dec.), p. 7312-19.
Raal, Ain., Kuznetsova, Irina. The effect of the method and duration of extraction on the content of biologically active compounds in herbal teas. Proceedings of the estonian academy of sciences, chemistry, 2007, vol. 56, no. 1, p. 53-56.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature