Botanical species · safety record
Argyreia nervosa
The EFSA Compendium of Botanicals holds 19 constituent measurements and 2 adverse-effect records for Argyreia nervosa. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Argyreia nervosa (Burm.f.) Bojer
Also recorded as
Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Lysergic acid5
- Ergine3
- Ergometrine3
- Chanoclavine-12
- Coumarins1
- Elymoclavine1
- Ergot alkaloids1
- Lysergol1
- Phenylpropanoids1
- Scopoletin1
Plant parts
- Seed17
- Roots and other underground parts2
- Unspecified1
Preparations
- Solvent extraction14
Effect types
- Musclo-skeletal1
- Neurotoxicity1
Target tissues
- Heart1
- Neurologic1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Chanoclavine-1 | Seed | — | 3.62 Percent | — | Resolve DOI |
| Chanoclavine-1 | Seed | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Coumarins | Roots and other underground parts | Solvent extraction | — | Phytochemical screening | Resolve DOI |
| Elymoclavine | Seed | — | — | — | Resolve DOI |
| Ergine | Seed | Solvent extraction | 780 Microgram/gram | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Ergine | Seed | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Ergine | Seed | Solvent extraction | 555 Microgram/gram | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Ergometrine | Seed | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Ergometrine | Seed | — | — | — | Resolve DOI |
| Ergometrine | Seed | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Ergot alkaloids | Seed | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Lysergic acid | Seed | Solvent extraction | ≥ 1.73 Microgram/0,01 gram | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Lysergic acid | Seed | — | 8.2 Percent | — | Resolve DOI |
| Lysergic acid | Seed | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Lysergol | Seed | Solvent extraction | — | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | Resolve DOI |
| Phenylpropanoids | Roots and other underground parts | Solvent extraction | — | Phytochemical screening | Resolve DOI |
| Lysergic acid | Seed | Solvent extraction | 0.04 Percent | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Lysergic acid | Seed | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | No resolvable identifier |
| Scopoletin | Unspecified | — | — | — | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Musclo-skeletal | Heart | Seed | — | Human (as organism) | Study with volunteers | Resolve DOI |
| Neurotoxicity | Neurologic | — | — | — | Acute toxicity | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Galani, Varsha J., Patel, Bharatkumar G. Psychotropic activity of Argyreia speciosa roots in experimental animals. . Ayu, 2011, vol. 32, no. 3, p. 380-4. DOI
- MILLER, MD. ISOLATION AND IDENTIFICATION OF LYSERGIC ACID AMIDE AND ISOLYSERGIC ACID AMIDE AS PRINCIPAL ERGOLINE ALKALOIDS IN ARGYREIA-NERVOSA, A TROPICAL WOOD ROSE . Journal of the association of official analytical chemists, 1970, vol. 53, no. 1, p. 123-&.
- Kremer, Christian., Paulke, Alexander., Wunder, Cora., Toennes, Stefan W. Variable adverse effects in subjects after ingestion of equal doses of Argyreia nervosa seeds . Forensic science international, 2012, vol. 214, no. 1-3, p. E6-E8. DOI
- Borsutzky, M., Passie, T., Paetzold, W., Emrich, HM., Schneider, U. Hawaiian baby woodrose: (Psycho-) pharmacological effects of the seeds of Argyreia nervosa. A case-orientated demonstration . Nervenarzt, 2002, vol. 73, no. 9, p. 892-896. DOI
- Paulke, Alexander., Kremer, Christian., Wunder, Cora., Wurglics, Mario., Schubert-Zsilavecz, Manfred., Toennes, Stefan W. Studies on the alkaloid composition of the Hawaiian Baby Woodrose Argyreia nervosa, a common legal high . Forensic science international, 2015, vol. 249, p. 281-293. DOI
- Srivastava, A., Shukla, YN. Aryl esters and a coumarin from Aygyreia speciosa. Indian journal of chemistry section b-organic chemistry including medicinal chemistry, 1998, vol. 37, no. 2, p. 192-194.
- HYLIN, JW., WATSON, DP. ERGOLINE ALKALOIDS IN TROPICAL WOOD ROSES. Science, 1965, vol. 148, no. 3669, p. 499-&. DOI
- Simonienko, K., Waszkiewicz, N., Szulc, A. Psychoactive plant species - Actual list of plants prohibited in Poland Roslinne srodki odurzajace - Aktualnie obowiazujaca lista w Polsce . Psychiatria polska, 2013, vol. 47, no. 3, p. 499-510.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
Continue
Europe PMC
Every record indexed for this species, resolvable and re-runnable.
All speciesSubstance index
Search and browse every species this world holds under source and hash.
Before anything elseSafety Centre
Interactions, contraindications and the escalation boundary this world does not cross.
In its own termsTraditions
How the living traditions approach preparation, use and context.