Botanical species · safety record

Aristolochia indica

The EFSA Compendium of Botanicals holds 13 constituent measurements and 6 adverse-effect records for Aristolochia indica. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Aristolochia indica L.

13Constituent measurements

6Safety records

4Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Aristolactam	Roots and other underground parts	Solvent extraction	—	—	Resolve DOI
Aristolactam	Live plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Aristolochia	Roots and other underground parts	Solvent extraction	—	—	Resolve DOI
Aristolochia	Roots and other underground parts	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Aristolochia	Roots and other underground parts	Solvent extraction	—	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	Resolve DOI
Aristolochia	Live plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Isoquinoline alkaloids	Live plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Isoquinoline alkaloids	Roots and other underground parts	Solvent extraction	—	Chromatographic tests	Resolve DOI
Magnoflorine	Roots and other underground parts	Solvent extraction	—	Chromatographic tests	Resolve DOI
Methyl aristolate	Roots and other underground parts	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Naphthoquinones	Roots and other underground parts	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Savinin	Roots and other underground parts	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Pinocarvone	Stem / stalk	Solvent extraction	14.2 Percent	GC-MS	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Reproductive	Urogenital	—	—	Rat (as animal)	Not reported	Resolve DOI
Reproductive	Urogenital	—	—	House mouse (as animal)	Not reported	Resolve DOI
Reproductive	Uterus	Roots and other underground parts	Solvent extraction	Rat (as animal)	Reproduction toxicity	Resolve DOI
Reproductive	Uterus	Roots and other underground parts	Solvent extraction	Rat (as animal)	Reproduction toxicity	Resolve DOI
Reproductive	Uterus	Roots and other underground parts	Solvent extraction	Hamster (as animal)	Reproduction toxicity	Resolve DOI
Systemic	Urogenital: kidneys	Unspecified	—	—	Case report	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

CHE, CT., AHMED, MS., KANG, SS., WALLER, DP., BINGEL, AS., MARTIN, A., RAJAMAHENDRAN, P., BUNYAPRAPHATSARA, N., LANKIN, DC., CORDELL, GA., SOEJARTO, DD., WIJESEKERA, ROB., FONG, HHS. STUDIES ON ARISTOLOCHIA .3. ISOLATION AND BIOLOGICAL EVALUATION OF CONSTITUENTS OF ARISTOLOCHIA-INDICA ROOTS FOR FERTILITY-REGULATING ACTIVITY . Journal of natural products, 1984, vol. 47, no. 2, p. 331-341. DOI
Michl, Johanna., Jennings, Hannah M., Kite, Geoffrey C., Ingrouille, Martin J., Simmonds, Monique S. J., Heinrich, Michael. Is aristolochic acid nephropathy a widespread problem in developing countries? A case study of Aristolochia indica L. in Bangladesh using an ethnobotanical-phytochemical approach . Journal of ethnopharmacology, 2013, vol. 149, no. 1, p. 235-244. DOI
Kumar, Dinesh., Kumar, Ajay., Prakash, Om. Potential antifertility agents from plants: A comprehensive review. JOURNAL OF ETHNOPHARMACOLOGY, 2012, vol. 140, no. 1, p. 1-32. DOI
Kanjilal, P. B., Kotoky, Rumi., Couladis, Maria. Chemical Composition of the Stein Oil of Aristolochia indica L.. Journal of essential oil research, 2009, vol. 21, no. 1, p. 24-25.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature