Botanical species · safety record
Arnebia euchroma
The EFSA Compendium of Botanicals holds 18 constituent measurements for Arnebia euchroma. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Arnebia euchroma (Royle) I.M.Johnst.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 54 licensed products naming Arnebia euchroma as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
What the records describe
Constituents measured
- Acetoxyisovalerylalkannin3
- Acetylshikonin3
- Shikonin3
- Beta,beta-dimethylacrylshikonin2
- Naphthoquinones2
- Camphor1
- Deoxyshikonin1
- Furan derivatives1
- Isobutylshikonin1
- Isovalerylshikonin1
Plant parts
- Roots and other underground parts18
Preparations
- Solvent extraction17
- Essential oil1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Acetoxyisovalerylalkannin | Roots and other underground parts | Solvent extraction | ≥ 1529 Microgram/gram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Acetoxyisovalerylalkannin | Roots and other underground parts | Solvent extraction | ≤ 4371 Microgram/gram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Acetoxyisovalerylalkannin | Roots and other underground parts | Solvent extraction | 6.5 Milligram/gram | HPLC-DAD | Resolve DOI |
| Acetylshikonin | Roots and other underground parts | Solvent extraction | 19.7 Milligram/gram | HPLC-DAD | Resolve DOI |
| Acetylshikonin | Roots and other underground parts | Solvent extraction | ≤ 1024 Microgram/gram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Acetylshikonin | Roots and other underground parts | Solvent extraction | ≥ 528 Microgram/gram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Beta,beta-dimethylacrylshikonin | Roots and other underground parts | Solvent extraction | ≥ 12.34 Milligram/gram | HPLC-DAD | Resolve DOI |
| Beta,beta-dimethylacrylshikonin | Roots and other underground parts | Solvent extraction | ≤ 11.66 Milligram/gram | HPLC-DAD | Resolve DOI |
| Deoxyshikonin | Roots and other underground parts | Solvent extraction | 0.262 Milligram/gram | HPLC-DAD | Resolve DOI |
| Furan derivatives | Roots and other underground parts | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Isobutylshikonin | Roots and other underground parts | Solvent extraction | 4.78 Milligram/gram | HPLC-DAD | Resolve DOI |
| Isovalerylshikonin | Roots and other underground parts | Solvent extraction | 14 Milligram/gram | HPLC-DAD | Resolve DOI |
| Naphthoquinones | Roots and other underground parts | Solvent extraction | 11.7 Milligram/gram | HPLC-DAD | Resolve DOI |
| Naphthoquinones | Roots and other underground parts | Solvent extraction | — | Standard Chromatographic tests (paper- thin layer- and column chromatography) | Resolve DOI |
| Shikonin | Roots and other underground parts | Solvent extraction | 1.52 Milligram/gram | HPLC-DAD | Resolve DOI |
| Shikonin | Roots and other underground parts | Solvent extraction | ≤ 207 Microgram/gram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Shikonin | Roots and other underground parts | Solvent extraction | ≥ 105 Microgram/gram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Camphor | Roots and other underground parts | Essential oil | 5.82 Percent | GC-MS | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Hu, Yani., Jiang, Zhihong., Leung, Kelvin Sze-Yin., Zhao, Zhongzhen. Simultaneous determination of naphthoquinone derivatives in Boraginaceous herbs by high-performance liquid chromatography. ANALYTICA CHIMICA ACTA, 2006, vol. 577, no. 1, p. 26-31. DOI
- Gu, Hongxia., Ji, Haiwei., Zhai, Jing. Analysis of the volatile oil from lithospermum erythrorhizon and arnebia euchroma by GC-MS.. Zhongguo yaofang, 2010, vol. 21, no. 27, p. 2546-2548.
- Wang, Lun., Li, Fu., Liu, Xin., Chen, Bin., Yu, Kai., Wang, Ming-Kui. Meroterpenoids and a Naphthoquinone from Arnebia euchroma and Their Cytotoxic Activity. PLANTA MEDICA, 2015, vol. 81, no. 4, p. 320-326. DOI
- Sharma, Nandini., Sharma, Upendra K., Gupta, Ajai P., Devla., Sinha, Arun K., Lal, Brij., Ahuja, Paramvir S. Simultaneous densitometric determination of shikonin, acetylshikonin, and beta-acetoxyisovaleryl-shikonin in ultrasonic-assisted extracts of four Arnebia species using reversed-phase thin layer chromatography. JOURNAL OF SEPARATION SCIENCE, 2009, vol. 32, no. 18, p. 3239-3245. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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