Botanical species · safety record

Artemisia afra

The EFSA Compendium of Botanicals holds 64 constituent measurements and 2 adverse-effect records for Artemisia afra. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Artemisia afra Jacq. ex Willd.

64Constituent measurements

2Safety records

14Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
(-)-globulol	Leaves	Essential oil	1.27 Percent	GC-MS	Resolve DOI
1,8-cineole	Leaves	Essential oil	8.91 Percent	GC-MS	Resolve DOI
1,8-cineole	Leaves	Essential oil	≤ 7.68 Percent	GC-MS	Resolve DOI
1,8-cineole	Leaves	Essential oil	≥ 7.2 Percent	GC-MS	Resolve DOI
1,8-cineole	Leaves	Essential oil	≤ 13.7 Percent	GC-MS	Resolve DOI
1,8-cineole	Leaves	Essential oil	≥ 13 Percent	GC-MS	Resolve DOI
1,8-cineole	Leaves	Essential oil	67.37 Percent	GC-MS	Resolve DOI
1,8-cineole	Aerial part of plants	Essential oil	≤ 29.3 Percent	GC-MS	Resolve DOI
1,8-cineole	Aerial part of plants	Essential oil	≥ 0.1 Percent	GC-MS	Resolve DOI
Alpha-thujone	Leaves	Essential oil	18.11 Percent	GC-MS	Resolve DOI
Alpha-thujone	Leaves	Essential oil	≤ 16.9 Percent	GC-MS	Resolve DOI
Alpha-thujone	Leaves	Essential oil	≥ 12.54 Percent	GC-MS	Resolve DOI
Alpha-thujone	Leaves	Essential oil	≤ 54.2 Percent	GC-MS	Resolve DOI
Alpha-thujone	Leaves	Essential oil	≥ 52.5 Percent	GC-MS	Resolve DOI
Alpha-thujone	Aerial part of plants	Essential oil	≤ 4.9 Percent	GC-MS	Resolve DOI
Alpha-thujone	Aerial part of plants	Essential oil	≥ 0.1 Percent	GC-MS	Resolve DOI
Anthraquinone	Aerial part of plants	Powder	—	Phytochemical screening	Resolve DOI
Artemisia ketone	Leaves	Essential oil	2.2 Percent	GC-MS	Resolve DOI
Artemisia ketone	Leaves	Essential oil	≤ 2 Percent	GC-MS	Resolve DOI
Artemisia ketone	Leaves	Essential oil	≥ 0.3 Percent	GC-MS	Resolve DOI
Artemisia ketone	Aerial part of plants	Essential oil	≤ 41.9 Percent	GC-MS	Resolve DOI
Artemisia ketone	Aerial part of plants	Essential oil	≥ 0.1 Percent	GC-MS	Resolve DOI
Beta-thujone	Leaves	Essential oil	≥ 13.1 Percent	GC-MS	Resolve DOI
Beta-thujone	Leaves	Essential oil	60.45 Percent	GC-MS	Resolve DOI
Beta-thujone	Leaves	Essential oil	≤ 60.63 Percent	GC-MS	Resolve DOI
Beta-thujone	Leaves	Essential oil	≥ 49.43 Percent	GC-MS	Resolve DOI
Beta-thujone	Leaves	Essential oil	≤ 13.7 Percent	GC-MS	Resolve DOI
Camphor	Aerial part of plants	Essential oil	≤ 50.3 Percent	GC-MS	Resolve DOI
Camphor	Leaves	Essential oil	≥ 6.6 Percent	GC-MS	Resolve DOI
Camphor	Aerial part of plants	Essential oil	≥ 6.2 Percent	GC-MS	Resolve DOI
Camphor	Leaves	Essential oil	≤ 8.8 Percent	GC-MS	Resolve DOI
Coumarins	Leaves	Solvent extraction	—	Unspecified	Resolve DOI
Isoalantolactone	Leaves	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Myrcene	Aerial part of plants	Essential oil	≤ 1.6 Percent	GC-MS	Resolve DOI
Myrcene	Aerial part of plants	Essential oil	≥ 0.1 Percent	GC-MS	Resolve DOI
Pinocarvone	Leaves	Essential oil	1.29 Percent	GC-MS	Resolve DOI
Saponins	Aerial part of plants	Powder	—	Phytochemical screening	Resolve DOI
Scopoletin	Leaves	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Tannins	Aerial part of plants	Powder	—	Phytochemical screening	Resolve DOI
1,8-cineole	Aerial part of plants	Essential oil	≤ 21.8 Percent	GC-MS	No resolvable identifier

40 of 64 records are shown, ordered so that records carrying a resolvable reference come first.

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Digestive: pancreas	Leaves	Solvent extraction	—	In vitro	No resolvable identifier
Digestive	Digestive: pancreas	Leaves	Solvent extraction	—	In vitro	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Chagonda, LS., Makanda, C., Chalchat, JC. The essential oil of cultivated Artemisia afra (Jacq.) from Zimbabwe. Flavour and fragrance journal, 1999, vol. 14, no. 2, p. 140-142. DOI
Libbey, L.M., Sturtz, G. Unusual essential oils grown in oregon. I. Artemisia afra jacq. Journal of essential oil research, 1989, vol. 1, no. 1, p. 29-31. DOI
Oyedeji, Adebola O., Afolayan, Anthony J., Hutchings, Anne. Compositional Variation of the Essential Oils of Artemisia afra Jacq. from three Provinces in South Africa - A Case Study of its Safety . Natural product communications, 2009, vol. 4, no. 6, p. 849-852.
Asekun, O. T., Grierson, D. S., Afolayan, A. J. Variations in the quality and yield of the essential oil from Artemisia afra using different drying methods . Journal of essential oil bearing plants, 2007, vol. 10, no. 1, p. 5-9.
JAKUPOVIC, J., KLEMEYER, H., BOHLMANN, F., GRAVEN, EH. GLAUCOLIDES AND GUAIANOLIDES FROM ARTEMISIA-AFRA. Phytochemistry, 1988, vol. 27, no. 4, p. 1129-1133.
Asfaw, Nigist., Demissew, Sebsebe. Essential oil composition of four Artemisia species from Ethiopia. Bulletin of the chemical society of ethiopia, 2015, vol. 29, no. 1, p. 123-128.
Ashafa, Anofi Omotayo Tom., Pitso, Teboho Raymond. Effects of Microwave Drying on the Yield and Chemical Composition of Essential Oils of Artemisia afra Jacq. Ex willd from the Eastern Free State South Africa . Journal of essential oil bearing plants, 2014, vol. 17, no. 6, p. 1087-1093. DOI
Nkobole, Nolitha., Houghton, Peter James., Hussein, Ahmed., Lall, Namrita. Antidiabetic Activity of Terminalia sericea Constituents. Natural product communications, 2011, vol. 6, no. 11, p. 1585-1588.
Issa, Idris Ahmed., Bule, Mohammed Hussen. Hypoglycemic Effect of Aqueous and Methanolic Extract of Artemisia afra on Alloxan Induced Diabetic Swiss Albino Mice . Evidence-based complementary and alternative medicine, 2015. DOI
Ntutela, Siyabulela., Smith, Pete., Matika, Lungile., Mukinda, James., Arendse, Hiram., Allie, Nasiema., Estes, D. Mark., Mabusela, Wilfred., Folb, Peter., Steyn, Lafras., Johnson, Quinton., Folk, William R., Syce, James., Jacobs, Muazzam. Efficacy of Artemisia afra phytotherapy in experimental Tuberculosis. Tuberculosis, 2009, vol. 89, p. S33-S40.
Guantai, AN., Addae-Mensah, I. Cardiovascular effect of Artemisia afra and its constituents. Pharmaceutical biology, 1999, vol. 37, no. 5, p. 351-356. DOI
Venables, L., Koekemoer, T. C., Van de Venter, M., Goosen, E. D. Isoalantolactone, a sesquiterpene lactone from Artemisia afra Jacq. ex Willd and its in vitro mechanism of induced cell death in HeLa cells . South african journal of botany, 2016, vol. 103, p. 216-221. DOI
Chinsembu, K.C. Tuberculosis and nature's pharmacy of putative anti-tuberculosis agents. Acta tropica, 2016, vol. 153, p. 46-56. DOI
Mwangi, J.W., Achola, K.J., Sinei, K.A., Lwande, W., Laurent, R. Essential oil constituents of artemisia afra willd. Journal of essential oil research, 1995, vol. 7, no. 1, p. 97-99. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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