Botanical species · safety record
Artemisia capillaris
The EFSA Compendium of Botanicals holds 7 constituent measurements, 1 adverse-effect record and 2 genotoxicity assays for Artemisia capillaris. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Artemisia capillaris Thunb.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 125 licensed products naming Artemisia capillaris as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
What the records describe
Constituents measured
- Coumarins2
- Eugenol2
- 1,8-cineole1
- Acenaphthylene1
- Scoparone1
Plant parts
- Flower3
- Live plants2
- Aerial part of plants1
- Leaves1
- Shoot1
Preparations
- Solvent extraction4
- Essential oil3
Effect types
- Digestive1
Target tissues
- Digestive1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Coumarins | Live plants | Solvent extraction | — | Colorimetry, Spectroscopy (Spectrometry) and Photometry | Resolve DOI |
| Scoparone | Shoot | Solvent extraction | — | Colorimetry, Spectroscopy (Spectrometry) and Photometry | Resolve DOI |
| 1,8-cineole | Flower | Essential oil | ≤ 1.3 Percent | GC-MS | No resolvable identifier |
| Acenaphthylene | Leaves | Solvent extraction | 37.91 Percent | GC-MS | No resolvable identifier |
| Coumarins | Aerial part of plants | — | — | Unspecified | No resolvable identifier |
| Eugenol | Flower | Essential oil | ≤ 15 Percent | GC-MS | No resolvable identifier |
| Eugenol | Flower | Essential oil | ≥ 4.3 Percent | GC-MS | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Digestive | Digestive | Live plants | Solvent extraction | — | In vitro | Resolve DOI |
Genotoxicity testing
Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.
| Outcome | Endpoint | Test | Tested organism | Metabolic activation | Source |
|---|---|---|---|---|---|
| Positive | DNA damage and/or repair | micronucleus assay | House mouse (as animal) | Not applicable | No resolvable identifier |
| Positive | chromosome aberration | chromosome aberration assay | House mouse (as animal) | Not applicable | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- YIN, XJ., LIU, DX., WANG, HC., ZHOU, Y. A STUDY ON THE MUTAGENICITY OF 102 RAW PHARMACEUTICALS USED IN CHINESE TRADITIONAL MEDICINE. MUTATION RESEARCH, 1991, vol. 260, no. 1, p. 73-82.
- Jang, SI., Kim, YJ., Lee, WY., Kwak, KC., Baek, SH., Kwak, GB., Yun, YG., Kwon, TO., Chung, HT., Chai, KY. Scoparone from Artemisia capillaris inhibits the release of inflammatory mediators in RAW 264.7 cells upon stimulation cells by interferon-gamma plus LPS. ARCHIVES OF PHARMACAL RESEARCH, 2005, vol. 28, no. 2, p. 203-208. DOI
- Islam, Md Nurul., Jung, Hyun Ah., Sohn, Hee Sook., Kim, Hye Mi., Choi, Jae Sue. Potent alpha-glucosidase and protein tyrosine phosphatase 1B inhibitors from Artemisia capillaris . Archives of pharmacal research, 2013, vol. 36, no. 5, p. 542-552. DOI
- Verma, R. S., Laiq-ur-Rahman., Verma, R. K., Chauhan, Amit., Singh, Anand., Chanotiya, C. S., Yadav, Anju., Singh, A. K., Kukreja, A. K., Khanuja, S. P. S. Essential Oil Composition of the Inflorescence of Artemisia capillaris Thunb. Collected at Different Stages of Flowering from Kumaon Region of Western Himalaya . Journal of essential oil research, 2010, vol. 22, no. 4, p. 340-343.
- Yun, KyeongWon. Phytotoxicity and Volatile Monoterpenes of Leaves from Artemisia capillaris and Artemisia iwayomogi Used as Korean Herbal Injin. Journal of Ecology and Environment, 2009, vol. 32, no. 1, p. 9-12.
- Kostova, I., Raleva, S., Genova, P., Argirova, R. Recent advances in the discovery and development of plant-derived natural coumarins and their analogues as anti human immunodeficiency virus - Type 1 (HIV-1) agents. Biotechnology and Biotechnological Equipment, 2005, vol. 19, no. 1, p. 16-22.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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