Botanical species · safety record

Artemisia frigida

The EFSA Compendium of Botanicals holds 21 constituent measurements and 1 adverse-effect record for Artemisia frigida. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Artemisia frigida Willd.

21Constituent measurements

1Safety records

8Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
1,8-cineole	Aerial part of plants	Essential oil	≤ 33.8 Percent Area	GC-MS	Resolve DOI
1,8-cineole	Aerial part of plants	Essential oil	≥ 8.9 Percent Area	GC-MS	Resolve DOI
1,8-cineole	Aerial part of plants	Essential oil	39.18 Percent Area	GC-MS	Resolve DOI
Alpha-thujone	Aerial part of plants	Essential oil	≤ 12.5 Percent Area	GC-MS	Resolve DOI
Alpha-thujone	Aerial part of plants	Essential oil	≥ 1 Percent Area	GC-MS	Resolve DOI
Beta-thujone	Aerial part of plants	Essential oil	≤ 6.6 Percent Area	GC-MS	Resolve DOI
Beta-thujone	Aerial part of plants	Essential oil	≥ 0.1 Percent Area	GC-MS	Resolve DOI
Camphor	Aerial part of plants	Essential oil	≤ 40 Percent Area	GC-MS	Resolve DOI
Camphor	Aerial part of plants	Essential oil	≥ 6.7 Percent Area	GC-MS	Resolve DOI
L-piperitone	Aerial part of plants	Essential oil	≥ 0.1 Percent Area	GC-MS	Resolve DOI
L-piperitone	Aerial part of plants	Essential oil	≤ 2 Percent Area	GC-MS	Resolve DOI
Myrcene	Aerial part of plants	Essential oil	≤ 3.4 Percent Area	GC-MS	Resolve DOI
Myrcene	Aerial part of plants	Essential oil	≥ 0.3 Percent Area	GC-MS	Resolve DOI
Santonin	Leaves	Solvent extraction	0.22 Gram/100 gram	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Sesquiterpene lactones	Leaves	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Sesquiterpene lactones	Aerial part of plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
1,8-cineole	Aerial part of plants	Essential oil	5.6 Percent Area	GC-MS	No resolvable identifier
Camphor	Aerial part of plants	Essential oil	2.261 Percent Area	GC-MS	No resolvable identifier
Coumarins	Aerial part of plants	Solvent extraction	—	Unspecified	No resolvable identifier
Myrcene	Aerial part of plants	Essential oil	2.201 Percent Area	GC-MS	No resolvable identifier
Sesquiterpene lactones	Unspecified	Solvent extraction	—	Unspecified	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Digestive	Aerial part of plants	Fresh	Sheep (as animal)	Short-term toxicity	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Korolyuk, E. A., Tkachev, A. V. Chemical composition of the essential oil from two wormwood species Artemisia frigida and Artemisia argyrophylla . Russian journal of bioorganic chemistry, 2010, vol. 36, no. 7, p. 884-893. DOI
Liu, Xiao-lan., Zhou, Jian-bo., Tao, Yan-duo., Shao, Yun. Analysis of chemical compositions of volatile oil in Artemisia frigida. Fenxi shiyanshi, 2008, vol. 27, no. 3, p. 25-29.
Zhang, Rumin., Zhang, Wenguang., Zuo, Zhaojiang., Li, Rui., Wu, Jianhua., Gao, Yan. Inhibition effects of volatile organic compounds from Artemisia frigida Willd. on the pasture grass intake by lambs . Small ruminant research, 2014, vol. 121, no. 2-3, p. 248-254. DOI
LIU, YL., MABRY, TJ. SESQUITERPENE LACTONES FROM ARTEMISIA-FRIGIDA. Journal of natural products, 1981, vol. 44, no. 6, p. 722-728. DOI
Wang, Q.-H., Wang, J.-H., Eerdunbagen., Tana. Chemical constituents of Artemisia frigida. Chinese traditional and herbal drugs, 2009, vol. 40, no. 10, p. 1540-1543.
Chen, Jinjun., Wang, Siming., Li, Cunfang., Zhang, Manli., Dong, Mei., Shi, Qingwen. Studies on the inhibitory effects of sesquiterpenoids from Artemisia frigida on the proliferation activity of human tumor cell lines and the structure-activity relationship. Zhongyao yaoli yu linchuang, 2011, vol. 27, no. 2, p. 24-26.
Wang, Qing-Hu., Sha, Yi., Ao, Wu-Li-Ji., Wang, Xiu-Lan., Bao, Xiao-Hua., Li, Wen., Wang, Jin-Hui. Two new sesquiterpene lactone glycosides from Artemisia frigida Willd.. Journal of asian natural products research, 2011, vol. 13, no. 7, p. 645-651. DOI
Sakipova, Zuriyadda., Wong, Nikki Siu Hai., Bekezhanova, Tolkyn., Sadykova., Shukirbekova, Alma., Boylan, Fabio. Quantification of santonin in eight species of Artemisia from Kazakhstan by means of HPLC-UV: Method development and validation . Plos one, 2017, vol. 12, no. 3. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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