Botanical species · safety record

Artemisia herba-alba

The EFSA Compendium of Botanicals holds 33 constituent measurements, 1 adverse-effect record and 2 genotoxicity assays for Artemisia herba-alba. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Artemisia herba-alba Asso

33Constituent measurements

3Safety records

9Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
1,8-cineole	Aerial part of plants	Essential oil	≤ 9.8 Percent	GC-MS	Resolve DOI
1,8-cineole	Aerial part of plants	Essential oil	≤ 11.4 Percent	GC-MS	Resolve DOI
1,8-cineole	Aerial part of plants	Essential oil	≥ 4.1 Percent	GC-MS	Resolve DOI
1,8-cineole	Aerial part of plants	Essential oil	≥ 3 Percent	GC-MS	Resolve DOI
1,8-cineole	Aerial part of plants	Essential oil	≤ 17 Percent	GC-FID	Resolve DOI
1,8-cineole	Aerial part of plants	Essential oil	≥ 6 Percent	GC-FID	Resolve DOI
Alpha-thujone	Aerial part of plants	Essential oil	≤ 44 Percent	GC-FID	Resolve DOI
Alpha-thujone	Aerial part of plants	Essential oil	≤ 47.1 Percent	GC-MS	Resolve DOI
Alpha-thujone	Aerial part of plants	Essential oil	≤ 28.1 Percent	GC-MS	Resolve DOI
Alpha-thujone	Aerial part of plants	Essential oil	≥ 9.2 Percent	GC-MS	Resolve DOI
Alpha-thujone	Aerial part of plants	Essential oil	≥ 6.9 Percent	GC-MS	Resolve DOI
Alpha-thujone	Aerial part of plants	Essential oil	≥ 7 Percent	GC-FID	Resolve DOI
Beta-thujone	Aerial part of plants	Essential oil	≤ 9.2 Percent	GC-MS	Resolve DOI
Beta-thujone	Aerial part of plants	Essential oil	≤ 7.8 Percent	GC-MS	Resolve DOI
Beta-thujone	Aerial part of plants	Essential oil	≥ 3 Percent	GC-MS	Resolve DOI
Beta-thujone	Aerial part of plants	Essential oil	≥ 1.9 Percent	GC-MS	Resolve DOI
Beta-thujone	Aerial part of plants	Essential oil	≤ 58 Percent	GC-FID	Resolve DOI
Beta-thujone	Aerial part of plants	Essential oil	≥ 17 Percent	GC-FID	Resolve DOI
Camphor	Aerial part of plants	Essential oil	≤ 33.1 Percent	GC-MS	Resolve DOI
Camphor	Aerial part of plants	Essential oil	≤ 30 Percent	GC-MS	Resolve DOI
Camphor	Aerial part of plants	Essential oil	≥ 5.6 Percent	GC-MS	Resolve DOI
Camphor	Aerial part of plants	Essential oil	≥ 17.3 Percent	GC-MS	Resolve DOI
Camphor	Aerial part of plants	Essential oil	≤ 11 Percent	GC-FID	Resolve DOI
Camphor	Aerial part of plants	Essential oil	≥ 4 Percent	GC-FID	Resolve DOI
Sesquiterpene lactones	Aerial part of plants	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
1,8-cineole	Aerial part of plants	Essential oil	8 Percent	GC-MS	No resolvable identifier
1,8-cineole	Leaves	Essential oil	7.88 Percent	GC-MS	No resolvable identifier
1,8-cineole	Aerial part of plants	Essential oil	9.4 Percent	Gaschromatography (GC)	No resolvable identifier
Alpha-thujone	Leaves	Essential oil	8.42 Percent	GC-MS	No resolvable identifier
Artemisia ketone	Aerial part of plants	Essential oil	13 Percent	GC-MS	No resolvable identifier
Beta-thujone	Leaves	Essential oil	12.7 Percent	GC-MS	No resolvable identifier
Camphor	Leaves	Essential oil	16.99 Percent	GC-MS	No resolvable identifier
Camphor	Aerial part of plants	Essential oil	9 Percent	Gaschromatography (GC)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Nephrotoxicity	Urogenital: kidneys	Aerial part of plants	Solvent extraction	Human (as organism)	Case report	Resolve DOI

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

Outcome	Endpoint	Test	Tested organism	Metabolic activation	Source
Positive	genome mutation	sister chromatid exchange assay in mammalian cells	House mouse (as animal)	—	Resolve DOI
Positive	chromosome aberration	micronucleus assay	House mouse (as animal)	—	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Aloui, Sabra., Skhiri, Hbib., Ltaief, Ahmed., Elmay, Mezri. An exceptional case of acute Renal failure: is there a renal toxicity of Artemisia herba-alba? . Renal failure, 2010, vol. 32, no. 8, p. 1009-1011. DOI
Abderrahman, Salim M., Shbailat, Seba Jamal. Genotoxic and cytotoxic effects of Artemisia herba-alba on mammalian cells. CARYOLOGIA, 2014, vol. 67, no. 4, p. 265-272. DOI
Laid, Messai., Hegazy, Mohamed-Elamir F., Ahmed, Ahmed A., Ali, Kalla., Belkacemi, Djaballah., Ohta, Shinji. Sesquiterpene lactones from Algerian Artemisia herba-alba. PHYTOCHEMISTRY LETTERS, 2008, vol. 1, no. 2, p. 85-88. DOI
Aouadi, D., Zorghi, L., Neffati, M., Ben Salem, H. The evaluation of the nutritional potential of five Mediterranean woody plants rich in phytocompounds . Journal of animal and feed sciences, 2015, vol. 24, no. 2, p. 160-165.
Mighri, Hedi., Akrout, Ahmed., Casanova, Joseph., Tomi, Felix., Neffati, Mohamed. Influence of Drying Time and Process on Artemisia herba-alba Asso Essential Oil Yield and Composition. JOURNAL OF ESSENTIAL OIL BEARING PLANTS, 2009, vol. 12, no. 3, p. 358-364.
Belhattab, Rachid., Amor, Loubna., Barroso, Jose G., Pedro, Luis G., Figueiredo, A. Cristina. Essential oil from Artemisia herba-alba Asso grown wild in Algeria: Variability assessment and comparison with an updated literature survey . Arabian journal of chemistry, 2014, vol. 7, no. 2, p. 243-251. DOI
Dahmani-Hamzaoui, Nacera., Baaliouamer, Aoumeur. Volatile constituents of Algerian Artemisia herba-alba essential oils. Journal of essential oil research, 2015, vol. 27, no. 5, p. 437-446. DOI
Mighri, Hedi., Akrout, Ahmed., El-jeni, Hajer., Zaidi, Slah., Tomi, Felix., Casanova, Joseph., Neffati, Mohamed. Composition and Intraspecific Chemical Variability of the Essential Oil from Artemisia herba-alba Growing Wild in a Tunisian Arid Zone . Chemistry & biodiversity, 2010, vol. 7, no. 11, p. 2709-2717. DOI
Tilaki, Ghasem Ali Dianati., Gholami, Farzaneh., Behtari, Behzad., Bezdi, Kamal Ghasemi. CHEMICAL COMPOSITION AND ALLELOPATHIC EFFECT OF THE ESSENTIAL OIL OF ARTEMISIA HERBA-ALBA ASSO. ON SEED GERMINATION AND EARLY SEEDLING GROWTH OF LEGUMES AND GRASSES SPECIES . Legume research, 2013, vol. 36, no. 1, p. 33-40.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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