Botanical species · safety record

Asarum europaeum

The EFSA Compendium of Botanicals holds 23 constituent measurements and 1 adverse-effect record for Asarum europaeum. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Asarum europaeum L.

23Constituent measurements

1Safety records

11Cited sources

10Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 10 licensed products naming Asarum europaeum as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

Plante entière
Tincture of the whole plant
Whole plant

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Aristolochia	Live plants	Solvent extraction	—	Unspecified	Resolve DOI
Asarone	Roots and other underground parts	Essential oil	≥ 485 Microgram/millilitre	GC-MS	Resolve DOI
Asarone	Roots and other underground parts	Essential oil	≤ 489 Microgram/millilitre	GC-MS	Resolve DOI
Beta-asarone	Roots and other underground parts	Essential oil	≥ 26.2 Microgram/millilitre	GC-MS	Resolve DOI
Beta-asarone	Roots and other underground parts	Essential oil	≤ 28 Microgram/millilitre	GC-MS	Resolve DOI
Methyleugenol	Roots and other underground parts	Essential oil	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Safrole	Live plants	Solvent extraction	≤ 0.021 Percent	Gaschromatography (GC)	Resolve DOI
Safrole	Live plants	Solvent extraction	≥ 0.017 Percent	Gaschromatography (GC)	Resolve DOI
Asarone	Unspecified	Essential oil	≥ 30 Percent	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Asarone	Unspecified	Essential oil	≤ 35 Percent	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Asarone	Aerial part of plants	Essential oil	59.1 Percent	GC-MS	No resolvable identifier
Benzaldehyde	Unspecified	Essential oil	≥ 2 Percent	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Benzaldehyde	Unspecified	Essential oil	≤ 3 Percent	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Beta-asarone	Aerial part of plants	Essential oil	1.3 Percent	GC-MS	No resolvable identifier
Beta-asarone	Leaves	Essential oil	11.5 Percent	Unspecified	No resolvable identifier
Beta-asarone	Roots and other underground parts	Essential oil	69.9 Percent	Unspecified	No resolvable identifier
Chlorogenic acid	Live plants	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Eugenol	Leaves	Essential oil	14.4 Percent	Unspecified	No resolvable identifier
Isoquercitrin	Live plants	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Lectins	Leaves	Solvent extraction	—	—	No resolvable identifier
Methyleugenol	Unspecified	Essential oil	≥ 15 Percent	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Methyleugenol	Unspecified	Essential oil	≤ 20 Percent	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Methyleugenol	Aerial part of plants	Essential oil	1.2 Percent	GC-MS	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Neurotoxicity	Neurologic: central nervous system	Roots and other underground parts	Solvent extraction	Human (as organism)	Case report	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Wilczewska, Agnieszka Z., Ulman, Magdalena., Chilmonczyk, Zdzislaw., Maj, Jadwiga., Koprowicz, Tomasz., Tomczyk, Michal., Tomczykowa, Monika. Comparison of volatile constituents of Acorus calamus and Asarum europaeum obtained by different techniques . Journal of essential oil research, 2008, vol. 20, no. 5, p. 390-395.
Brandle, W., Gurtner, B., Wegmann, T. Hemiparesis in an abortion attempt with hazelwort tea decoction (Asarum europaeum) . . Praxis, 1969, vol. 58, no. 27, p. 868-9.
Nitzsche, Dana., Melzig, Matthias F., Arlt, Volker M. Evaluation of the cytotoxicity and genotoxicity of aristolochic acid I - A component of Aristolochiaceae plant extracts used in homeopathy . Environmental toxicology and pharmacology, 2013, vol. 35, no. 2, p. 325-334. DOI
Bruckner, Viktor., Szeki, Tibor. Composition of asarum oil. Journal fuer praktische chemie (leipzig), 1932, vol. 134, p. 107-40.
Oprean, R., Tamas, M., Roman, L. Comparison of GC-MS and TLC techniques for asarone isomers determination. Journal of pharmaceutical and biomedical analysis, 1998, vol. 18, no. 1-2, p. 227-234. DOI
Galambosi, Bertalan., Galambosi, Zsuzsanna Sz., Hethelyi, Eva B., Szoke, Eva. The leaf and root yield and essential oil content of the round-leaved Asarum (Asarum europaeum L.) in South Finland. Olaj, szappan, kozmetika, 2009, vol. 58(1-2), p. 12-16.
Gracza, Lajos., Csizer, Eva U. The active principles of Asarum europaeum. V. Aromatic hydroxy carboxylic acids. Magyar kemiai folyoirat, 1965, vol. 71, no. 6, p. 242-4.
Antonyuk, V. A., Lutsik, M. D., Ladnaya, L. Ya. Seasonal variations in hemagglutination titers and affinity to carbohydrates of plant extracts containing fucose-specific lectins. Fiziologiya rastenii (moscow), 1982, vol. 29, no. 6, p. 1219-24.
Rzadkowska-Bodalska, H., Bieganowska, M. L., Cisowski, W. Chromatographic analysis of flavonoid fraction of Asarum europaeum L. herb and roots. Herba polonica, 1987, vol. 33, no. 3, p. 167-73.
Stuppner, H., Ganzera, M. Determination of safrole in different Asarum species by headspace gas chromatography.. Chromatographia, 1998, vol. 47, no. 11/12, p. 685-688. DOI
GRACZA, L. THE ACTIVE SUBSTANCES OF ASARUM-EUROPAEUM .16. THE LOCAL-ANESTHETIC ACTIVITY OF THE PHENYLPROPANOIDS . Planta medica, 1983, vol. 48, no. 3, p. 153-157. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

Continue

Independent literature