Botanical species · safety record

Asarum heterotropoides

The EFSA Compendium of Botanicals holds 33 constituent measurements for Asarum heterotropoides. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Asarum heterotropoides F.Schmidt

33Constituent measurements

0Safety records

7Cited sources

1Licensed products (Canada)

Also recorded as

Asiasarum heterotropoides (F.Schmidt) F.Maek.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 1 licensed products naming Asarum heterotropoides as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

Herb(s)

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Aristolactam	Roots and other underground parts	Solvent extraction	≤ 0.07 Milligram/gram	HPLC with standard detection methods	Resolve DOI
Aristolactam	Roots and other underground parts	Solvent extraction	≥ 0.03 Milligram/gram	HPLC with standard detection methods	Resolve DOI
Aristolochia	Unspecified	Solvent extraction	42.2 Microgram/gram	HPLC-UV	Resolve DOI
Aristolochia	Roots and other underground parts	Solvent extraction	≤ 0.16 Milligram/gram	HPLC with standard detection methods	Resolve DOI
Aristolochia	Roots and other underground parts	Solvent extraction	≥ 0.07 Milligram/gram	HPLC with standard detection methods	Resolve DOI
Asarinin	Roots and other underground parts	Solvent extraction	≤ 2.6 Milligram/gram	HPLC with standard detection methods	Resolve DOI
Asarinin	Roots and other underground parts	Solvent extraction	≥ 1.7 Milligram/gram	HPLC with standard detection methods	Resolve DOI
Asarone	Live plants	Solvent extraction	—	Gaschromatography (GC)	Resolve DOI
Elemicin	Unspecified	Essential oil	≥ 5 Percent	—	Resolve DOI
Elemicin	Unspecified	Essential oil	≤ 42 Percent	—	Resolve DOI
Kakuol	Roots and other underground parts	Solvent extraction	≤ 0.25 Milligram/gram	HPLC with standard detection methods	Resolve DOI
Kakuol	Roots and other underground parts	Solvent extraction	≥ 0.11 Milligram/gram	HPLC with standard detection methods	Resolve DOI
Methyleugenol	Unspecified	Essential oil	≤ 63 Percent	—	Resolve DOI
Methyleugenol	Unspecified	Essential oil	≥ 20 Percent	—	Resolve DOI
Methyleugenol	Roots and other underground parts	Solvent extraction	≤ 0.5 Milligram/gram	HPLC with standard detection methods	Resolve DOI
Methyleugenol	Roots and other underground parts	Solvent extraction	≥ 0.15 Milligram/gram	HPLC with standard detection methods	Resolve DOI
Myristicin	Roots and other underground parts	Solvent extraction	≤ 0.78 Milligram/gram	HPLC with standard detection methods	Resolve DOI
Myristicin	Roots and other underground parts	Solvent extraction	≥ 0.04 Milligram/gram	HPLC with standard detection methods	Resolve DOI
Phenylethylamines	Unspecified	Solvent extraction	—	Gaschromatography (GC)	Resolve DOI
Pluviatilol	Roots and other underground parts	Solvent extraction	≥ 0.14 Milligram/gram	HPLC with standard detection methods	Resolve DOI
Pluviatilol	Roots and other underground parts	Solvent extraction	≤ 0.21 Milligram/gram	HPLC with standard detection methods	Resolve DOI
Safrole	Roots and other underground parts	Solvent extraction	≤ 0.43 Milligram/gram	HPLC with standard detection methods	Resolve DOI
Safrole	Roots and other underground parts	Solvent extraction	≥ 0.25 Milligram/gram	HPLC with standard detection methods	Resolve DOI
Safrole	Unspecified	Essential oil	≤ 32 Percent	—	Resolve DOI
Safrole	Unspecified	Essential oil	≥ 3 Percent	—	Resolve DOI
Aristolochia	Live plants	—	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Asarinin	Roots and other underground parts	—	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Asarinin	Live plants	—	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	No resolvable identifier
Coumarins	Roots and other underground parts	—	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Methyleugenol	Unspecified	Essential oil	22.9 Percent	GC-MS	No resolvable identifier
Myristicin	Roots and other underground parts	—	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier
Safrole	Unspecified	Essential oil	19.8 Percent	GC-MS	No resolvable identifier
Safrole	Roots and other underground parts	—	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Wen, Hao., Gao, Hui-yuan., Qi, Wen., Xiao, Feng., Wang, Li-li., Wang, Dong., Yuan, Dan. Simultaneous Determination of Twenty-Two Components in Asari Radix et Rhizoma by Ultra Performance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry. PLANTA MEDICA, 2014, vol. 80, no. 18, p. 1753-1762. DOI
Stuppner, H., Ganzera, M. Determination of safrole in different Asarum species by headspace gas chromatography.. Chromatographia, 1998, vol. 47, no. 11/12, p. 685-688. DOI
Wang, B., Qi, W., Wang, L., Kong, D., Kano, Y., Li, J., Yuan, D. Comparative study of chemical composition, antinociceptive effect and acute toxicity of the essential oils of three Asarum drugs. Journal of chinese pharmaceutical sciences, 2014, vol. 23, no. 7, p. 480-489. DOI
Qi, Wen., Wang, Li-li., Wen, Hao., Wang, Wei-ning., Zhang, Lin., Yuan, Dan. Isolation and identification of chemical constituents in roots and rhizomes of Asarum heterotropoides Fr. Schmidt var. mandshuricum (Maxim.) Kitag.. Shenyang yaoke daxue xuebao, 2014, vol. 31, no. 9, p. 681-686, 691.
Han, Jun-yan., Wang, Jun., Han, Xue., Ji, Ming-shan. Effects of essential oil from asarum heterotropoides on toxicity and related enzymes of tetranychus urticae.. Tianran chanwu yanjiu yu kaifa, 2012, vol. 24, no. 4, p. 525-528.
Song, Shuang-hong., Se, Lin-ge., Chen, Bei., Cui, Lang-jun., Shang, Peng. Determination of aristolochic acid I and asarinin in four species of Asari Radix et Rhizoma by HPLC.. Zhongchengyao, 2014, vol. 36, no. 8, p. 1711-1715.
Jong, TT., Lee, MR., Hsiao, SS., Hsai, JL., Wu, TS., Chiang, ST., Cai, SQ. Analysis of aristolochic acid in nine sources of Xixin, a traditional Chinese medicine, by liquid chromatography/atmospheric pressure chemical ionization/tandem mass spectrometry. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2003, vol. 33, no. 4, p. 831-837. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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