Botanical species · safety record

Asclepias currassavica

The EFSA Compendium of Botanicals holds 28 constituent measurements for Asclepias currassavica. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Asclepias currassavica L.

28Constituent measurements
0Safety records
7Cited sources
0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Cardenolides5
  • Pregnane derivatives2
  • Steroidal alkaloids2
  • Steroidal saponins2
  • Alkaloids1
  • Asclepin1
  • Ascleposide1
  • Calactinic acid methyl ester1
  • Calotropagenin1
  • Calotropin1

Plant parts

  • Aerial part of plants18
  • Roots and other underground parts4
  • Seed3
  • Live plants2
  • Stem1
  • stalk1

Preparations

  • Solvent extraction27

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
AsclepinAerial part of plantsSolvent extraction17.4 Milligram/kilogramNuclear Magnetic Resonance (NMR)Resolve DOI
AscleposideAerial part of plantsSolvent extraction1.1 Milligram/kilogramNuclear Magnetic Resonance (NMR)Resolve DOI
Calactinic acid methyl esterAerial part of plantsSolvent extraction> 1.5 Milligram/kilogramNuclear Magnetic Resonance (NMR)Resolve DOI
CalotropageninAerial part of plantsSolvent extraction15.6 Milligram/kilogramNuclear Magnetic Resonance (NMR)Resolve DOI
CalotropinAerial part of plantsSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
CalotropinsAerial part of plantsSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
CannogenolAerial part of plantsSolvent extraction16 Milligram/kilogramNuclear Magnetic Resonance (NMR)Resolve DOI
CardenolidesAerial part of plantsSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
CardenolidesLive plantsSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
CardenolidesAerial part of plantsSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
CardenolidesAerial part of plantsSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
Curassavoside bAerial part of plantsSolvent extraction2 Milligram/kilogramNuclear Magnetic Resonance (NMR)Resolve DOI
DesglucouzarinAerial part of plantsSolvent extraction11 Milligram/kilogramNuclear Magnetic Resonance (NMR)Resolve DOI
DigitoxigeninAerial part of plantsSolvent extraction> 1.2 Milligram/kilogramNuclear Magnetic Resonance (NMR)Resolve DOI
KidjolaninRoots and other underground partsSolvent extraction> 9.5 Milligram/kilogramColorimetry, Spectroscopy (Spectrometry) and PhotometryResolve DOI
Pregnane derivativesLive plantsSolvent extractionNuclear Magnetic Resonance (NMR)Resolve DOI
Pregnane derivativesRoots and other underground partsSolvent extractionColorimetry, Spectroscopy (Spectrometry) and PhotometryResolve DOI
SarcostinAerial part of plantsSolvent extraction> 1 Milligram/kilogramNuclear Magnetic Resonance (NMR)Resolve DOI
Steroidal alkaloidsAerial part of plantsSolvent extraction> 4 Milligram/kilogramNuclear Magnetic Resonance (NMR)Resolve DOI
Steroidal alkaloidsRoots and other underground partsSolvent extraction14.3 Milligram/kilogramColorimetry, Spectroscopy (Spectrometry) and PhotometryResolve DOI
Steroidal saponinsRoots and other underground partsSolvent extraction> 11.9 Milligram/kilogramColorimetry, Spectroscopy (Spectrometry) and PhotometryResolve DOI
Steroidal saponinsAerial part of plantsSolvent extraction> 6.9 Milligram/kilogramNuclear Magnetic Resonance (NMR)Resolve DOI
UscharidinAerial part of plantsSolvent extraction31.4 Milligram/kilogramNuclear Magnetic Resonance (NMR)Resolve DOI
UscharinAerial part of plantsSolvent extraction0.8 Milligram/kilogramNuclear Magnetic Resonance (NMR)Resolve DOI
AlkaloidsStem / stalkColorimetry, Spectroscopy (Spectrometry) and PhotometryNo resolvable identifier
CardenolidesSeedSolvent extractionNuclear Magnetic Resonance (NMR)No resolvable identifier
FrugosidSeedSolvent extraction1.162 Milligram/gramNuclear Magnetic Resonance (NMR)No resolvable identifier
FrugosidesSeedSolvent extractionNuclear Magnetic Resonance (NMR)No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Li, Jun-Zhu., Qing, Chen., Chen, Chang-Xiang., Hao, Xiao-Jiang., Liu, Hai-Yang. Cytotoxicity of cardenolides and cardenolide glycosides from Asclepias curassavica. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, vol. 19, no. 7, p. 1956-1959. DOI
  2. Roy, MC., Chang, FR., Huang, HC., Chiang, MYN., Wu, YC. Cytotoxic principles from the Formosan milkweed, Asclepias curassavica. JOURNAL OF NATURAL PRODUCTS, 2005, vol. 68, no. 10, p. 1494-1499. DOI
  3. Zhang, Rong-Rong., Tian, Hai-Yan., Tan, Ya-Fang., Chung, Tse-Yu., Sun, Xiao-Hui., Xia, Xue., Ye, Wen-Cai., Middleton, David A., Fedosova, Natalya., Esmann, Mikael., Tzen, Jason T. C., Jiang, Ren-Wang. Structures, chemotaxonomic significance, cytotoxic and Na+, K+-ATPase inhibitory activities of new cardenolides from Asclepias curassavica. ORGANIC & BIOMOLECULAR CHEMISTRY, 2014, vol. 12, no. 44, p. 8919-8929. DOI
  4. Demarco, Diego. Micromorphology and Histochemistry of the Laticifers from Vegetative Organs of Asclepiadoideae species (Apocynaceae). Acta Biologica Colombiana, 2015, vol. 20, no. 1, p. 57-65.
  5. Warashina, Tsutomu., Noro, Tadataka. Steroidal glycosides from the roots of Asclepias curassavica.. Chemical & pharmaceutical bulletin, 2008, vol. 56, no. 3, p. 315-22. DOI
  6. ABE, F., MORI, Y., YAMAUCHI, T. CARDENOLIDE GLYCOSIDES FROM THE SEEDS OF ASCLEPIAS-CURASSAVICA. CHEMICAL & PHARMACEUTICAL BULLETIN, 1992, vol. 40, no. 11, p. 2917-2920.
  7. Li, Jun-Zhu., Liu, Hai-Yang., Lin, Yi-Ju., Hao, Xiao-Jiang., Ni, Wei., Chen, Chang-Xiang. Six new C(21) steroidal glycosides from Asclepias curassavica L.. STEROIDS, 2008, vol. 73, no. 6, p. 594-600. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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