Botanical species · safety record
Asclepias currassavica
The EFSA Compendium of Botanicals holds 28 constituent measurements for Asclepias currassavica. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Asclepias currassavica L.
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Cardenolides5
- Pregnane derivatives2
- Steroidal alkaloids2
- Steroidal saponins2
- Alkaloids1
- Asclepin1
- Ascleposide1
- Calactinic acid methyl ester1
- Calotropagenin1
- Calotropin1
Plant parts
- Aerial part of plants18
- Roots and other underground parts4
- Seed3
- Live plants2
- Stem1
- stalk1
Preparations
- Solvent extraction27
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Asclepin | Aerial part of plants | Solvent extraction | 17.4 Milligram/kilogram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Ascleposide | Aerial part of plants | Solvent extraction | 1.1 Milligram/kilogram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Calactinic acid methyl ester | Aerial part of plants | Solvent extraction | > 1.5 Milligram/kilogram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Calotropagenin | Aerial part of plants | Solvent extraction | 15.6 Milligram/kilogram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Calotropin | Aerial part of plants | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Calotropins | Aerial part of plants | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Cannogenol | Aerial part of plants | Solvent extraction | 16 Milligram/kilogram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Cardenolides | Aerial part of plants | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Cardenolides | Live plants | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Cardenolides | Aerial part of plants | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Cardenolides | Aerial part of plants | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Curassavoside b | Aerial part of plants | Solvent extraction | 2 Milligram/kilogram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Desglucouzarin | Aerial part of plants | Solvent extraction | 11 Milligram/kilogram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Digitoxigenin | Aerial part of plants | Solvent extraction | > 1.2 Milligram/kilogram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Kidjolanin | Roots and other underground parts | Solvent extraction | > 9.5 Milligram/kilogram | Colorimetry, Spectroscopy (Spectrometry) and Photometry | Resolve DOI |
| Pregnane derivatives | Live plants | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Pregnane derivatives | Roots and other underground parts | Solvent extraction | — | Colorimetry, Spectroscopy (Spectrometry) and Photometry | Resolve DOI |
| Sarcostin | Aerial part of plants | Solvent extraction | > 1 Milligram/kilogram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Steroidal alkaloids | Aerial part of plants | Solvent extraction | > 4 Milligram/kilogram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Steroidal alkaloids | Roots and other underground parts | Solvent extraction | 14.3 Milligram/kilogram | Colorimetry, Spectroscopy (Spectrometry) and Photometry | Resolve DOI |
| Steroidal saponins | Roots and other underground parts | Solvent extraction | > 11.9 Milligram/kilogram | Colorimetry, Spectroscopy (Spectrometry) and Photometry | Resolve DOI |
| Steroidal saponins | Aerial part of plants | Solvent extraction | > 6.9 Milligram/kilogram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Uscharidin | Aerial part of plants | Solvent extraction | 31.4 Milligram/kilogram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Uscharin | Aerial part of plants | Solvent extraction | 0.8 Milligram/kilogram | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
| Alkaloids | Stem / stalk | — | — | Colorimetry, Spectroscopy (Spectrometry) and Photometry | No resolvable identifier |
| Cardenolides | Seed | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
| Frugosid | Seed | Solvent extraction | 1.162 Milligram/gram | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
| Frugosides | Seed | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Li, Jun-Zhu., Qing, Chen., Chen, Chang-Xiang., Hao, Xiao-Jiang., Liu, Hai-Yang. Cytotoxicity of cardenolides and cardenolide glycosides from Asclepias curassavica. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, vol. 19, no. 7, p. 1956-1959. DOI
- Roy, MC., Chang, FR., Huang, HC., Chiang, MYN., Wu, YC. Cytotoxic principles from the Formosan milkweed, Asclepias curassavica. JOURNAL OF NATURAL PRODUCTS, 2005, vol. 68, no. 10, p. 1494-1499. DOI
- Zhang, Rong-Rong., Tian, Hai-Yan., Tan, Ya-Fang., Chung, Tse-Yu., Sun, Xiao-Hui., Xia, Xue., Ye, Wen-Cai., Middleton, David A., Fedosova, Natalya., Esmann, Mikael., Tzen, Jason T. C., Jiang, Ren-Wang. Structures, chemotaxonomic significance, cytotoxic and Na+, K+-ATPase inhibitory activities of new cardenolides from Asclepias curassavica. ORGANIC & BIOMOLECULAR CHEMISTRY, 2014, vol. 12, no. 44, p. 8919-8929. DOI
- Demarco, Diego. Micromorphology and Histochemistry of the Laticifers from Vegetative Organs of Asclepiadoideae species (Apocynaceae). Acta Biologica Colombiana, 2015, vol. 20, no. 1, p. 57-65.
- Warashina, Tsutomu., Noro, Tadataka. Steroidal glycosides from the roots of Asclepias curassavica.. Chemical & pharmaceutical bulletin, 2008, vol. 56, no. 3, p. 315-22. DOI
- ABE, F., MORI, Y., YAMAUCHI, T. CARDENOLIDE GLYCOSIDES FROM THE SEEDS OF ASCLEPIAS-CURASSAVICA. CHEMICAL & PHARMACEUTICAL BULLETIN, 1992, vol. 40, no. 11, p. 2917-2920.
- Li, Jun-Zhu., Liu, Hai-Yang., Lin, Yi-Ju., Hao, Xiao-Jiang., Ni, Wei., Chen, Chang-Xiang. Six new C(21) steroidal glycosides from Asclepias curassavica L.. STEROIDS, 2008, vol. 73, no. 6, p. 594-600. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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