Botanical species · safety record
Atractylodes japonica
The EFSA Compendium of Botanicals holds 1 constituent measurement and 1 adverse-effect record for Atractylodes japonica. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Atractylodes japonica Koidz. ex Kitam.
Regulatory presence
No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.
What the records describe
Constituents measured
- Polyacetylene derivatives1
Plant parts
- Roots and other underground parts2
Preparations
- Solvent extraction2
Effect types
- Hepatotoxicity1
Target tissues
- Liver1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Polyacetylene derivatives | Roots and other underground parts | Solvent extraction | — | Nuclear Magnetic Resonance (NMR) | Resolve DOI |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Hepatotoxicity | Liver | Roots and other underground parts | Solvent extraction | House mouse (as animal) | Short-term toxicity | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Sung, Hye-Young., Cho, Sung-Hee., Choi, Young-Sun., Lee, Hyang-Rim., Choi, Sang-Won. Effects of Methanol Extracts of Rubus Coreanus Miquel and Atractylodes Japonica Koidzumi on Hepatic Toxicity and Immunomodulating Activity in Mice . Nutritional sciences, 2006, vol. 9, no. 2, p. 68-73.
- Choi, Keun Han., Jeong, Seung Il., Lee, Jun Ho., Hwang, Byung Soon., Lee, Seoul., Choi, Bong Kyu., Jung, Kyu Yong. Acetylene compound isolated from Atractylodes japonica stimulates the contractility of rat distal colon via inhibiting the nitrergic-purinergic relaxation. JOURNAL OF ETHNOPHARMACOLOGY, 2011, vol. 134, no. 1, p. 104-110. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
Continue
Europe PMC
Every record indexed for this species, resolvable and re-runnable.
All speciesSubstance index
Search and browse every species this world holds under source and hash.
Before anything elseSafety Centre
Interactions, contraindications and the escalation boundary this world does not cross.
In its own termsTraditions
How the living traditions approach preparation, use and context.