Botanical species · safety record
Atractylodes macrocephala
The EFSA Compendium of Botanicals holds 1 constituent measurement and 2 adverse-effect records for Atractylodes macrocephala. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Atractylodes macrocephala Koidz.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 1,676 licensed products naming Atractylodes macrocephala as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Extract types on licence
Source material stated
What the records describe
Constituents measured
- Atractyloside1
Plant parts
- Roots and other underground parts3
Preparations
- Solvent extraction3
Effect types
- Reproductive1
- Teratogenic1
Target tissues
- Muscle, skeletal1
- Urogenital1
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| Atractyloside | Roots and other underground parts | Solvent extraction | 9230 Microgram/gram | GC-MS | No resolvable identifier |
Recorded adverse effects
Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.
| Effect | Target tissue | Plant part | Preparation | Test organism | Test type | Source |
|---|---|---|---|---|---|---|
| Reproductive | Urogenital | Roots and other underground parts | Solvent extraction | House mouse (as animal) | Reproduction toxicity | No resolvable identifier |
| Teratogenic | Muscle, skeletal | Roots and other underground parts | Solvent extraction | Rabbit (as animal) | Reproduction toxicity | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- Li, L., Tang, L. Y., Man, Gene C. W., Yeung, Benson H. Y., Lau, Clara B. S., Leung, P. C., Wang, C. C. Potential reproductive toxicity of Largehead Atractylodes Rhizome, the most commonly used Chinese medicine for threatened miscarriage.. Human reproduction, 2011, vol. 26, no. 12, p. 3280-3288.
- Chen, Liang-Yu., Hu, Anren., Chang, Chih-Jui. The degradation mechanism of toxic atractyloside in herbal medicines by decoction.. Molecules, 2013, vol. 18, p. 2018-2028.
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
Continue
Europe PMC
Every record indexed for this species, resolvable and re-runnable.
All speciesSubstance index
Search and browse every species this world holds under source and hash.
Before anything elseSafety Centre
Interactions, contraindications and the escalation boundary this world does not cross.
In its own termsTraditions
How the living traditions approach preparation, use and context.