Botanical species · safety record

Averrhoa carambola

The EFSA Compendium of Botanicals holds 3 constituent measurements and 5 adverse-effect records for Averrhoa carambola. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Averrhoa carambola L.

3Constituent measurements
5Safety records
5Cited sources
0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Oxalates1
  • Saponins1
  • Tannins1

Plant parts

  • Fruit unspecified6
  • Leaves2

Preparations

  • Solvent extraction3
  • Sap (as part-nature)1

Effect types

  • Nephrotoxicity2
  • Neurotoxicity2
  • Hepatotoxicity1

Target tissues

  • Neurologic: central nervous system2
  • Urogenital: kidneys2
  • Liver1

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
SaponinsLeavesSolvent extraction—Phytochemical screeningResolve DOI
TanninsLeavesSolvent extraction—Phytochemical screeningResolve DOI
OxalatesFruit unspecifiedSolvent extraction2.42 Gram/100 millilitreElement spectroscopyNo resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
HepatotoxicityLiverFruit unspecifiedSap (as part-nature)Rat (as animal)Short-term toxicityResolve DOI
NeurotoxicityNeurologic: central nervous systemFruit unspecified—Human (as organism)Case reportResolve DOI
NephrotoxicityUrogenital: kidneysFruit unspecified—Rat (as animal)Acute toxicityNo resolvable identifier
NephrotoxicityUrogenital: kidneysFruit unspecified—Rat (as animal)Acute toxicityNo resolvable identifier
NeurotoxicityNeurologic: central nervous systemFruit unspecified—Human (as organism)Case reportNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Fang, Hua-Chang., Lee, Po-Tsang., Lu, Pei-Jung., Chen, Chien-Liang., Chang, Tsu-Yuan., Hsu, Chih-Yang., Chung, Hsiao-Min., Chou, Kang-Ju. Mechanisms of star fruit-induced acute renal failure.. Food and chemical toxicology, 2008, vol. 46, no. 5, p. 1744-1752.
  2. Khoo, Z. Y., Teh, C. C., Rao, N. K., Chin, J. H. Evaluation of the toxic effect of star fruit on serum biochemical parameters in rats . Pharmacognosy magazine, 2010, vol. 6, no. 22, p. 120-124. DOI
  3. Tse, KC., Yip, PS., Lam, MF., Choy, BY., Li, FK., Lui, SL., Lo, WK., Chan, TM., Lai, KN. Star fruit intoxication in uraemic patients: case series and review of the literature . Internal medicine journal, 2003, vol. 33, no. 7, p. 314-316. DOI
  4. Chen, CL., Chou, KJ., Wang, JS., Yeh, JH., Fang, HC., Chung, HM. Neurotoxic effects of carambola in rats: The role of oxalate. Journal of the formosan medical association, 2002, vol. 101, no. 5, p. 337-341.
  5. Vasconcelos, CML., Araujo, MS., Silva, BA., Conde-Garcia, EA. Negative inotropic and chronotropic effects on the guinea pig atrium of extracts obtained from Averrhoa carambola L. leaves . Brazilian journal of medical and biological research, 2005, vol. 38, no. 7, p. 1113-1122. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

Continue