Botanical species · safety record

Averrhoa carambola

The EFSA Compendium of Botanicals holds 3 constituent measurements and 5 adverse-effect records for Averrhoa carambola. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Averrhoa carambola L.

3Constituent measurements

5Safety records

5Cited sources

0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Saponins	Leaves	Solvent extraction	—	Phytochemical screening	Resolve DOI
Tannins	Leaves	Solvent extraction	—	Phytochemical screening	Resolve DOI
Oxalates	Fruit unspecified	Solvent extraction	2.42 Gram/100 millilitre	Element spectroscopy	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Hepatotoxicity	Liver	Fruit unspecified	Sap (as part-nature)	Rat (as animal)	Short-term toxicity	Resolve DOI
Neurotoxicity	Neurologic: central nervous system	Fruit unspecified	—	Human (as organism)	Case report	Resolve DOI
Nephrotoxicity	Urogenital: kidneys	Fruit unspecified	—	Rat (as animal)	Acute toxicity	No resolvable identifier
Nephrotoxicity	Urogenital: kidneys	Fruit unspecified	—	Rat (as animal)	Acute toxicity	No resolvable identifier
Neurotoxicity	Neurologic: central nervous system	Fruit unspecified	—	Human (as organism)	Case report	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Tse, KC., Yip, PS., Lam, MF., Choy, BY., Li, FK., Lui, SL., Lo, WK., Chan, TM., Lai, KN. Star fruit intoxication in uraemic patients: case series and review of the literature . Internal medicine journal, 2003, vol. 33, no. 7, p. 314-316. DOI
Vasconcelos, CML., Araujo, MS., Silva, BA., Conde-Garcia, EA. Negative inotropic and chronotropic effects on the guinea pig atrium of extracts obtained from Averrhoa carambola L. leaves . Brazilian journal of medical and biological research, 2005, vol. 38, no. 7, p. 1113-1122. DOI
Chen, CL., Chou, KJ., Wang, JS., Yeh, JH., Fang, HC., Chung, HM. Neurotoxic effects of carambola in rats: The role of oxalate. Journal of the formosan medical association, 2002, vol. 101, no. 5, p. 337-341.
Khoo, Z. Y., Teh, C. C., Rao, N. K., Chin, J. H. Evaluation of the toxic effect of star fruit on serum biochemical parameters in rats . Pharmacognosy magazine, 2010, vol. 6, no. 22, p. 120-124. DOI
Fang, Hua-Chang., Lee, Po-Tsang., Lu, Pei-Jung., Chen, Chien-Liang., Chang, Tsu-Yuan., Hsu, Chih-Yang., Chung, Hsiao-Min., Chou, Kang-Ju. Mechanisms of star fruit-induced acute renal failure.. Food and chemical toxicology, 2008, vol. 46, no. 5, p. 1744-1752.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature