Botanical species · safety record

Bacopa monnieri

The EFSA Compendium of Botanicals holds 8 constituent measurements and 2 genotoxicity assays for Bacopa monnieri. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Bacopa monnieri (L.) Wettst.

8Constituent measurements

2Safety records

3Cited sources

686Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 686 licensed products naming Bacopa monnieri as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Dry
Fresh

Source material stated

Aerial flowering part
Aerial parts
Aerial parts (standardized extract)
Aerial parts extract
Aerial parts from flower
Bacopa monnieri - Herb
Bacopa monnieri - Herb top
Bacopa monnieri - Leaf

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Bacoside a	Aerial part of plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Bacoside b	Aerial part of plants	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Alkaloids	Leaves	—	—	Traditional analytical techniques (wet chemical tests)	No resolvable identifier
Alkaloids	Stem / stalk	—	—	Traditional analytical techniques (wet chemical tests)	No resolvable identifier
Saponins	Leaves	—	—	Traditional analytical techniques (wet chemical tests)	No resolvable identifier
Saponins	Stem / stalk	—	—	Traditional analytical techniques (wet chemical tests)	No resolvable identifier
Tannins	Leaves	—	—	Traditional analytical techniques (wet chemical tests)	No resolvable identifier
Tannins	Stem / stalk	—	—	Traditional analytical techniques (wet chemical tests)	No resolvable identifier

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

Outcome	Endpoint	Test	Tested organism	Metabolic activation	Source
Positive	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	Human (as organism)	Not applicable	Resolve DOI
Positive	chromosome aberration	in vitro mammalian chromosome aberration test	Human (as organism)	Not applicable	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Dhale, D.A. Histochemical investigation of two plant species valued as Medhya rasayanas. International journal of pharma and bio sciences, 2012, vol. 3, no. 2, p. 122-129.
D'Souza, P., Deepak, M., Rani, P., Kadamboor, S., Mathew, A., Chandrashekar, AP., Agarwal, A. Brine shrimp lethality essay of Bacopa monnieri. Phytotherapy research, 2002, vol. 16, no. 2, p. 197-198. DOI
Kalachaveedu, M., Papacchan, S., Sanyal, S., Koshy, T., Telapolu, S. Isolation and evaluation of cytogenetic effect of Brahmi saponins on cultured human lymphocytes exposed in vitro. Natural Product Research, 2015, vol. 29, no. 12, p. 1118-1121. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature