Botanical species · safety record

Bidens pilosa

The EFSA Compendium of Botanicals holds 8 constituent measurements, 1 adverse-effect record and 1 genotoxicity assay for Bidens pilosa. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Bidens pilosa L.

8Constituent measurements

2Safety records

7Cited sources

3Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 3 licensed products naming Bidens pilosa as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

Whole plant(s)

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Eugenol	Leaves	Solvent extraction	—	—	Resolve DOI
Eugenol	Roots and other underground parts	Solvent extraction	—	—	Resolve DOI
Gallic acid	Live plants	Solvent extraction	—	—	Resolve DOI
P-coumaric acid	Live plants	Solvent extraction	—	—	Resolve DOI
Polyynes	Live plants	Solvent extraction	—	Unspecified	Resolve DOI
Pyrrolizidine alkaloids	Leaves	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Saponins	Leaves	Solvent extraction	—	Phytochemical screening	Resolve DOI
Tannins	Unspecified	Solvent extraction	—	—	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Reproductive	Uterus	Roots and other underground parts	Solvent extraction	Rat (as animal)	In vitro	Resolve DOI

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

Outcome	Endpoint	Test	Tested organism	Metabolic activation	Source
Positive	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	Mammals (as animal)	—	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Bartolome, Arlene P., Villasenor, Irene M., Yang, Wen-Chin. Bidens pilosa L. (Asteraceae): Botanical Properties, Traditional Uses, Phytochemistry, and Pharmacology. . Evidence-based complementary and alternative medicine : ecam, 2013, vol. 2013, p. 340215. DOI
Nikolajsen, Tine., Nielsen, Frank., Rasch, Vibeke., Sorensen, Pernille H., Ismail, Flora., Kristiansen, Uffe., Jager, Anna K. Uterine contraction induced by Tanzanian plants used to induce abortion. Journal of ethnopharmacology, 2011, vol. 137, no. 1, p. 921-925. DOI
Costa, Ronaldo de Jesus., Diniz, Andrea., Mantovani, Mario Sergio., Jordao, Berenice Quinzani. In vitro study of mutagenic potential of Bidens pilosa Linne and Mikania glomerata Sprengel using the comet and micronucleus assays. . Journal of ethnopharmacology, 2008, vol. 118, no. 1, p. 86-93. DOI
Kone, W.M., Kande, B. Qualitative analysis of the pyrrolizidine alkaloids from 11 asteraceae and boraginaceae used in traditional medicine in cote d'lvoire. Research journal of phytochemistry, 2012, vol. 6, no. 3, p. 75-83. DOI
Souza, Bruna A., Da Silva, Lidiane C., Chicarino, Evelyn D., Bessa, Elisabeth C. A. Preliminary phytochemical screening and molluscicidal activity of the aqueous extract of Bidens pilosa Linne (Asteraceae) in Subulina octona (Mollusca, Subulinidade). ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS, 2013, vol. 85, no. 4, p. 1557-1566. DOI
Arroyo, Jorge., Bonilla, Pablo., R�ez, Ernesto., Su�rez, Silvia., Palomino, Robert., Ter�n, Segundo., Villarreal, An�bal., Marin, Manuel., Chenguay�n, Julio., Justil, Hugo. Compuestos fen�licos de la fracci�n metan�lica de Bidens pilosa, sobre la neoplasia g�strica, inducida en ratas . Anales de la facultad de medicina, 2007, vol. 68, no. 2, p. 105-112.
Yang, Wen-Chin. Botanical, Pharmacological, Phytochemical, and Toxicological Aspects of the Antidiabetic Plant Bidens pilosa L. . Evidence-based complementary and alternative medicine : ecam, 2014, vol. 2014, p. 698617-698617. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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