Botanical species · safety record

Bixa orellana

The EFSA Compendium of Botanicals holds 1 constituent measurement and 2 genotoxicity assays for Bixa orellana. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Bixa orellana L.

1Constituent measurements

2Safety records

3Cited sources

14Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 14 licensed products naming Bixa orellana as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

Bixa orellana - Seed
Fruit
Seed extract
Seed(s)

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Alkaloids	Unspecified	Solvent extraction	—	—	Resolve DOI

Genotoxicity testing

Outcomes of genotoxicity assays as recorded in the source. A negative assay is a result under those test conditions, not a clearance.

Outcome	Endpoint	Test	Tested organism	Metabolic activation	Source
Positive	gene mutation	in vitro	Other	—	No resolvable identifier
Positive	—	dominant lethal assay	Rat (as animal)	—	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Aranez, Adoracion T., Rubio, Raquel O. Genotoxicity of pigments from seeds of Bixa orellana L. (atsuete) I. Determined by Allium test. Philippine journal of science, 1996, p. 259-269.
Aranez, Adoracion T., Bayot, Elmo. Genotoxicity of pigments from seeds of Bixa orellana L. (Atsuete) II. determined by lethal test. Philippine journal of science, 1997, p. 163-173.
Coe, F.G., Parikh, D.M., Johnson, C.A. Alkaloid presence and brine shrimp (Artemia salina) bioassay of medicinal species of eastern Nicaragua. Pharmaceutical Biology, 2010, vol. 48, no. 4, p. 439-445. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature