Botanical species · safety record

Boerhavia diffusa

The EFSA Compendium of Botanicals holds 14 constituent measurements for Boerhavia diffusa. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Boerhavia diffusa L.

14Constituent measurements

0Safety records

8Cited sources

61Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 61 licensed products naming Boerhavia diffusa as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Herb
Herb top
Herb top and root
Leaf
Root
Root extract
Seed(s)
Tuber

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Boeravinone b	Roots and other underground parts	Solvent extraction	0.014 Percent	HPLC-DAD	Resolve DOI
Gallic acid	Roots and other underground parts	Solvent extraction	8.66 Milligram/gram	HPLC-DAD	Resolve DOI
Punarnavine	Aerial part of plants	Solvent extraction	0.01 Percent	Unspecified	Resolve DOI
Punarnavine	Roots and other underground parts	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Rotenoids	—	—	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Rotenoids	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Rotenoids	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Boeravinone b	Aerial part of plants	Solvent extraction	≤ 105 Microgram/millilitre	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	No resolvable identifier
Boeravinone b	Aerial part of plants	Solvent extraction	≥ 15 Microgram/millilitre	Gelpermeation, High Performance Thin Layer Chromatography (HPTLC)	No resolvable identifier
Calcium oxalate	Live plants	Solvent extraction	—	Chromatographic tests	No resolvable identifier
Liriodendrin	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Saponins	Live plants	Solvent extraction	—	Chromatographic tests	No resolvable identifier
Syringaresinol	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Tannins	Live plants	Solvent extraction	—	Chromatographic tests	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Edeoga, H. O., Ikem, C. I. Tannins, saponins and calcium oxalate crystals from Nigerian species of Boerhavia L. (Nyctaginaceae). . South african journal of botany, 2002, vol. 68, no. 4, p. 386-388.
Tacchini, Massimo., Spagnoletti, Antonella., Marieschi, Matteo., Caligiani, Augusta., Bruni, Renato., Efferth, Thomas., Sacchetti, Gianni., Guerrini, Alessandra. Phytochemical profile and bioactivity of traditional ayurvedic decoctions and hydro-alcoholic macerations of Boerhaavia diffusa L. and Curculigo orchioides Gaertn. . Natural product research, 2015, vol. 29, no. 22, p. 2071-2079. DOI
LAMI, N., KADOTA, S., KIKUCHI, T., MOMOSE, Y. CONSTITUENTS OF THE ROOTS OF BOERHAAVIA-DIFFUSA L .3. IDENTIFICATION OF CA-2+ CHANNEL ANTAGONISTIC COMPOUND FROM THE METHANOL EXTRACT . Chemical & pharmaceutical bulletin, 1991, vol. 39, no. 6, p. 1551-1555.
Manu, K. A., Kuttan, Girija. Effect of Punarnavine, an alkaloid from Boerhaavia diffusa, on cell-mediated immune responses and TIMP-1 in B16F-10 metastatic melanoma-bearing mice . Immunopharmacology and immunotoxicology, 2007, vol. 29, no. 3-4, p. 569-586. DOI
Aher, Vaibhav., Chattopadhyay, Pronobesh., Goyary, Danswrang., Veer, Vijay. Evaluation of the Genotoxic and Antigenotoxic Potential of the Alkaloid Punarnavine from Boerhaavia diffusa . Planta medica, 2013, vol. 79, no. 11, p. 939-945. DOI
Borrelli, F., Milic, N., Ascione, V., Capasso, R., Izzo, AA., Capasso, F., Petrucci, F., Valente, R., Fattorusso, E., Taglialatela-Scafati, O. Isolation of new rotenoids from Boerhaavia diffusa and evaluation of their effect on intestinal motility . Planta medica, 2005, vol. 71, no. 10, p. 928-932. DOI
Ahmed-Belkacem, Abdelhakim., Macalou, Sira., Borrelli, Francesca., Capasso, Raffaele., Fattorusso, Ernesto., Taglialatela-Scafati, Orazio., Di Pietro, Attilio. Nonprenylated rotenoids, a new class of potent breast cancer resistance protein inhibitors . Journal of medicinal chemistry, 2007, vol. 50, no. 8, p. 1933-1938. DOI
Gomes, A.D., Vaidya, V.V., Bhagat, R.D., Gadgil, J.N. Separation and quantification of pharmacologically active markers Boeravinone B, Eupalitin-3-O-beta-D-galactopyranoside and beta-sitosterol from Boeravia diffusa Linn. and from marketed formulation. International journal of pharmacy and pharmaceutical sciences, 2013, vol. 5, no. 3, p. 953-956.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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