Botanical species · safety record

Borago officinalis

The EFSA Compendium of Botanicals holds 9 constituent measurements for Borago officinalis. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Borago officinalis L.

9Constituent measurements
0Safety records
5Cited sources
727Licensed products (Canada)

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 727 licensed products naming Borago officinalis as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

  • Aerial parts
  • Borage seed oil
  • Borago officinalis
  • Borago officinalis - seed
  • Clupeidae - Whole
  • Fish oil
  • Grain
  • Grain(s)

What the records describe

Constituents measured

  • Pyrrolizidine alkaloids4
  • 2-pentylfuran1
  • Berberine1
  • Furfural1
  • Sanguinarine1
  • Saponins1

Plant parts

  • Seed4
  • Flower3
  • Stem1
  • Unspecified1
  • stalk1

Preparations

  • Solvent extraction7

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
2-pentylfuranSeedSolvent extraction1.9 Percent AreaGC-MSResolve DOI
BerberineFlowerSolvent extraction0.003534 PercentPhytochemical screeningResolve DOI
FurfuralSeedSolvent extraction1.8 Percent AreaGC-MSResolve DOI
Pyrrolizidine alkaloidsSeed≤ 0.5 Microgram/kilogramHPLC with standard detection methodsResolve DOI
Pyrrolizidine alkaloidsUnspecifiedUnspecifiedResolve DOI
SanguinarineFlowerSolvent extraction0.01174 PercentPhytochemical screeningResolve DOI
SaponinsFlowerSolvent extraction6.451 Milligram/100 gramPhytochemical screeningResolve DOI
Pyrrolizidine alkaloidsSeedSolvent extraction0.08 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
Pyrrolizidine alkaloidsStem / stalkSolvent extraction0.07 PercentHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. These, Anja., Bodi, Dorina., Ronczka, Stefan., Lahrssen-Wiederholt, Monika., Preiss-Weigert, Angelika. Structural screening by multiple reaction monitoring as a new approach for tandem mass spectrometry: presented for the determination of pyrrolizidine alkaloids in plants. Analytical and bioanalytical chemistry, 2013, vol. 405, no. 29, p. 9375-9383.
  2. Cramer, Luise., Fleck, Gunther., Horn, Gert., Beuerle, Till. Process Development of Lappula squarrosa Oil Refinement: Monitoring of Pyrrolizidine Alkaloids in Boraginaceae Seed Oils. JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 2014, vol. 91, no. 5, p. 721-731. DOI
  3. Wu, Shimin., Xu, Ting., Huang, Danfeng. Chemical compositions of the volatile extracts from seeds of Dendranthema nankingense and Borago officinalis . Journal of food and drug analysis, 2015, vol. 23, no. 2, p. 253-259. DOI
  4. Mohajer, Sadegh., Taha, Rosna Mat., Bin Ramli, Rosli., Mohajer, Minoo. Phytochemical constituents and radical scavenging properties of Borago officinalis and Malva sylvestris . Industrial crops and products, 2016, vol. 94, p. 673-681. DOI
  5. Roeder, E., Wiedenfeld, H., Edgar, J. A. Pyrrolizidine alkaloids in medicinal plants from North America. Pharmazie, 2015, vol. 70, no. 6, p. 357-367. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

Continue