Botanical species · safety record
Borago officinalis
The EFSA Compendium of Botanicals holds 9 constituent measurements for Borago officinalis. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.
Accepted name in source: Borago officinalis L.
Regulatory presence
Health Canada's Licensed Natural Health Products Database holds 727 licensed products naming Borago officinalis as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.
Source material stated
What the records describe
Constituents measured
- Pyrrolizidine alkaloids4
- 2-pentylfuran1
- Berberine1
- Furfural1
- Sanguinarine1
- Saponins1
Plant parts
- Seed4
- Flower3
- Stem1
- Unspecified1
- stalk1
Preparations
- Solvent extraction7
Recorded constituents
What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.
| Substance | Plant part | Preparation | Concentration | Analytical method | Source |
|---|---|---|---|---|---|
| 2-pentylfuran | Seed | Solvent extraction | 1.9 Percent Area | GC-MS | Resolve DOI |
| Berberine | Flower | Solvent extraction | 0.003534 Percent | Phytochemical screening | Resolve DOI |
| Furfural | Seed | Solvent extraction | 1.8 Percent Area | GC-MS | Resolve DOI |
| Pyrrolizidine alkaloids | Seed | — | ≤ 0.5 Microgram/kilogram | HPLC with standard detection methods | Resolve DOI |
| Pyrrolizidine alkaloids | Unspecified | — | — | Unspecified | Resolve DOI |
| Sanguinarine | Flower | Solvent extraction | 0.01174 Percent | Phytochemical screening | Resolve DOI |
| Saponins | Flower | Solvent extraction | 6.451 Milligram/100 gram | Phytochemical screening | Resolve DOI |
| Pyrrolizidine alkaloids | Seed | Solvent extraction | 0.08 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
| Pyrrolizidine alkaloids | Stem / stalk | Solvent extraction | 0.07 Percent | High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC) | No resolvable identifier |
Cited sources
The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.
- These, Anja., Bodi, Dorina., Ronczka, Stefan., Lahrssen-Wiederholt, Monika., Preiss-Weigert, Angelika. Structural screening by multiple reaction monitoring as a new approach for tandem mass spectrometry: presented for the determination of pyrrolizidine alkaloids in plants. Analytical and bioanalytical chemistry, 2013, vol. 405, no. 29, p. 9375-9383.
- Cramer, Luise., Fleck, Gunther., Horn, Gert., Beuerle, Till. Process Development of Lappula squarrosa Oil Refinement: Monitoring of Pyrrolizidine Alkaloids in Boraginaceae Seed Oils. JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 2014, vol. 91, no. 5, p. 721-731. DOI
- Wu, Shimin., Xu, Ting., Huang, Danfeng. Chemical compositions of the volatile extracts from seeds of Dendranthema nankingense and Borago officinalis . Journal of food and drug analysis, 2015, vol. 23, no. 2, p. 253-259. DOI
- Mohajer, Sadegh., Taha, Rosna Mat., Bin Ramli, Rosli., Mohajer, Minoo. Phytochemical constituents and radical scavenging properties of Borago officinalis and Malva sylvestris . Industrial crops and products, 2016, vol. 94, p. 673-681. DOI
- Roeder, E., Wiedenfeld, H., Edgar, J. A. Pyrrolizidine alkaloids in medicinal plants from North America. Pharmazie, 2015, vol. 70, no. 6, p. 357-367. DOI
Boundary
A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.
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