Botanical species · safety record

Brucea antidysenterica

The EFSA Compendium of Botanicals holds 6 constituent measurements for Brucea antidysenterica. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Brucea antidysenterica J.F.Mill.

6Constituent measurements

0Safety records

5Cited sources

0Licensed products (Canada)

Also recorded as

Brucea ferruginea L'Hér.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Quassinoids	Bark	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Quassinoids	Stem / stalk	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Quassinoids	Unspecified	—	—	Unspecified	Resolve DOI
Quassinoids	Stem / stalk	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Indole alkaloids	Stem / stalk	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier
Indole alkaloids	Stem / stalk	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

KUPCHAN, SM., BRITTON, RW., LACADIE, JA., ZIEGLER, MF., SIGEL, CW. ISOLATION AND STRUCTURAL ELUCIDATION OF BRUCEANTIN AND BRUCEANTINOL, NEW POTENT ANTILEUKEMIC QUASSINOIDS FROM BRUCEA-ANTIDYSENTERICA. JOURNAL OF ORGANIC CHEMISTRY, 1975, vol. 40, no. 5, p. 648-654. DOI
Imamura, K., Fukamiya, N., Nakamura, M., Okano, M., Tagahara, K., Lee, KH. Bruceanols G and H, cytotoxic quassinoids from Brucea antidysenterica. JOURNAL OF NATURAL PRODUCTS, 1995, vol. 58, no. 12, p. 1915-1919. DOI
Fukamiya, Narihiko., Okano, Masayoshi., Aratani, Takaaki., Negoro, Kenji., Lin, Yuh Meei., Lee, Kuo Hsiung. Antitumor agents: LXXXXVII. Cytotoxic antileukemic canthin-6-one alkaloids from Brucea antidysenterica and the structure activity relationships of their related derivatives. Planta Medica, 1987, p. 140-143.
Cuendet, M., Pezzuto, JM. Antitumor activity of bruceantin: An old drug with new promise. JOURNAL OF NATURAL PRODUCTS, 2004, vol. 67, no. 2, p. 269-272. DOI
TOYOTA, T., FUKAMIYA, N., OKANO, M., TAGAHARA, K., CHANG, JJ., LEE, KH. ANTITUMOR AGENTS .118. THE ISOLATION AND CHARACTERIZATION OF BRUCEANIC ACID-A, ITS METHYL-ESTER, AND THE NEW BRUCEANIC ACID-B, ACID-C, AND ACID-D, FROM BRUCEA-ANTIDYSENTERICA. JOURNAL OF NATURAL PRODUCTS, 1990, vol. 53, no. 6, p. 1526-1532. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature