Botanical species · safety record

Brucea javanica

The EFSA Compendium of Botanicals holds 7 constituent measurements and 2 adverse-effect records for Brucea javanica. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Brucea javanica (L.) Merr.

7Constituent measurements

2Safety records

4Cited sources

5Licensed products (Canada)

Also recorded as

Rhus javanica L.

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 5 licensed products naming Brucea javanica as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Extract types on licence

Source material stated

Fruit

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Lignans	Seed	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Pregnane derivatives	Seed	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Quassinoids	Seed	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Quassinoids	Seed	Solvent extraction	—	High Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)	Resolve DOI
Quassinoids	Seed	Solvent extraction	—	Colorimetry, Spectroscopy (Spectrometry) and Photometry	Resolve DOI
Quassinoids	Seed	Solvent extraction	0.4 Percent/volume	UV/VIS spectroscopy (photometry)	No resolvable identifier
Quassinoids	Seed	Solvent extraction	10.3 Percent/volume	UV/VIS spectroscopy (photometry)	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Cardiovascular / haematological	Seed	Solvent extraction	House mouse (as animal)	Acute toxicity	No resolvable identifier
Not reported	—	Seed	Solvent extraction	House mouse (as animal)	Acute toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Shahida, Ajmi Noor., Choo, Chee Yan., Wong, Tin Wui. Acute/subchronic oral toxicity of Brucea javanica seeds with hypoglycemic activity . Journal of natural remedies, 2011, vol. 11, no. 1, p. 60-68.
Dong, Shi-Hui., Liu, Jia., Ge, Ying-Zi., Dong, Lei., Xu, Cheng-Hui., Ding, Jian., Yue, Jian-Min. Chemical constituents from Brucea javanica. Phytochemistry, 2013, vol. 85, p. 175-184. DOI
Liu, Jun-Hong., Zhao, Nan., Zhang, Gui-Jie., Yu, Shi-Shan., Wu, Li-Jun., Qu, Jing., Ma, Shuang-Gang., Chen, Xiao-Guang., Zhang, Tian-Qi., Bai, Jian., Chen, Hui., Fang, Zhen-Feng., Zhao, Fen., Tang, Wei-Bin. Bioactive Quassinoids from the Seeds of Brucea javanica. Journal of natural products, 2012, vol. 75, no. 4, p. 683-688. DOI
Liu, Jie-Qing., Wang, Cui-Fang., Li, Xing-Yao., Chen, Jian-Chao., Li, Yan., Qiu, Ming-Hua. One New Pregnane Glycoside from the Seeds of Cultivated Brucea javanica. Archives of pharmacal research, 2011, vol. 34, no. 8, p. 1297-1300. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature