Botanical species · safety record

Brugmansia suaveolens

The EFSA Compendium of Botanicals holds 18 constituent measurements and 2 adverse-effect records for Brugmansia suaveolens. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Brugmansia suaveolens (Humb. & Bonpl. ex Willd.) Bercht. & J.Presl

18Constituent measurements
2Safety records
8Cited sources
0Licensed products (Canada)

Also recorded as

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Scopolamine12
  • Tropane alkaloids3
  • 1,8-cineole2
  • Alkaloids1

Plant parts

  • Flower7
  • Leaves4
  • Stem3
  • stalk3
  • Fruit unspecified2
  • Roots and other underground parts2
  • Live plants1
  • Unspecified1

Preparations

  • Solvent extraction18
  • Thermal treatment (heating for preservation)1

Effect types

  • Neurotoxicity2

Target tissues

  • Neurologic2

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
ScopolamineFlowerSolvent extraction≥ 1.3 Milligram/gramResolve DOI
ScopolamineFlowerSolvent extraction≤ 1.5 Milligram/gramResolve DOI
ScopolamineFruit unspecifiedSolvent extraction≥ 1.8 Milligram/gramResolve DOI
ScopolamineFruit unspecifiedSolvent extraction≤ 2 Milligram/gramResolve DOI
ScopolamineLeavesSolvent extraction≥ 0.8 Milligram/gramResolve DOI
ScopolamineLeavesSolvent extraction≤ 1.1 Milligram/gramResolve DOI
ScopolamineRoots and other underground partsSolvent extraction≥ 0.1 Milligram/gramResolve DOI
ScopolamineRoots and other underground partsSolvent extraction≤ 0.3 Milligram/gramResolve DOI
ScopolamineStem / stalkSolvent extraction≥ 0.8 Milligram/gramResolve DOI
ScopolamineStem / stalkSolvent extraction≤ 1 Milligram/gramResolve DOI
1,8-cineoleFlowerSolvent extraction≥ 2 PercentGC-MSNo resolvable identifier
1,8-cineoleFlowerSolvent extraction≤ 72.1 PercentGC-MSNo resolvable identifier
AlkaloidsFlowerSolvent extraction0.64 PercentColorimetry, Spectroscopy (Spectrometry) and PhotometryNo resolvable identifier
ScopolamineFlowerSolvent extractionHigh Performance Liquid Chromatography (HPLC)/Liquid Chromatography (LC)No resolvable identifier
ScopolamineLeavesSolvent extraction80 PercentStandard Chromatographic tests (paper- thin layer- and column chromatography)No resolvable identifier
Tropane alkaloidsLive plantsSolvent extractionColorimetry, Spectroscopy (Spectrometry) and PhotometryNo resolvable identifier
Tropane alkaloidsStem / stalkSolvent extraction2.37 PercentUnspecifiedNo resolvable identifier
Tropane alkaloidsLeavesSolvent extraction0.318 PercentUnspecifiedNo resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

EffectTarget tissuePlant partPreparationTest organismTest typeSource
NeurotoxicityNeurologicFlowerHuman (as organism)Case reportResolve DOI
NeurotoxicityNeurologicUnspecifiedThermal treatment (heating for preservation)Human (as organism)Case reportNo resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Chang, S.-S., Wu, M.-L., Deng, J.-F., Lee, C.-C., Chin, T.-F., Liao, S.-J. Poisoning by Datura leaves used as edible wild vegetables. Veterinary and Human Toxicology, 1999, vol. 41, no. 4, p. 242-245.
  2. Anthony, Samuel J., Zuchowski, Willow., Setzer, William N. Composition of the Floral Essential Oil of Brugmansia suaveolens. Records of natural products, 2009, vol. 3, no. 2, p. 76-81.
  3. Sevketoglu, Esra., Tatli, Burak., Tugcu, Betul., Demirelli, Yasar., Hatipoglu, Sami. An Unusual Cause of Fulminant Guillain-Barre Syndrome: Angel's Trumpet. PEDIATRIC NEUROLOGY, 2010, vol. 43, no. 5, p. 368-370. DOI
  4. Evans, W. C., Lampard, J. F. Alkaloids of the genus Datura section Brugmansia. VIII. Alkaloids of Datura suaveolens. Phytochemistry (Elsevier), 1972, p. 3293-3298.
  5. Kerchner Andras., Darok Judit., Bacskay Ivett., Felinger Attila., Jakab Gabor., Farkas Agnes. Protein and alkaloid patterns of the floral nectar in some solanaceous species. Acta biologica hungarica, 2015, p. 304-315.
  6. Alves, Marcos Nopper., Sartoratto, Adilson., Trigo, Jose Roberto. Scopolamine in Brugmansia suaveolens (Solanaceae): Defense, allocation, costs, and induced response . Journal of chemical ecology, 2007, vol. 33, no. 2, p. 297-309. DOI
  7. Grupta, B. K., Vishwa, Paul., Handa, K. L., Kapoor, L. D. Hyoscine is the chief constituent of Datura suaveolens leaves. proceedings of the national academy of sciences, india, section a: physical sciences, 1965, p. 261-262.
  8. Balbaa, S. I., Saber, A. Hifny., Karawya, M. S., El-Hossary, G. A. Alkaloid content of Datura suaveolens grown in Egypt. journal of pharmaceutical sciences of the united arab republic, 1969, p. 125-134.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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