Botanical species · safety record

Brunfelsia grandiflora

The EFSA Compendium of Botanicals holds 20 constituent measurements and 1 adverse-effect record for Brunfelsia grandiflora. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Brunfelsia grandiflora D.Don.

20Constituent measurements

1Safety records

7Cited sources

0Licensed products (Canada)

Also recorded as

Brunfelsia grandiflora subsp. grandiflora

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Brunfelsamidine	Roots and other underground parts	Solvent extraction	—	—	Resolve DOI
Brunfelsamidine	Roots and other underground parts	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Cirensenoside p	Leaves	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Methyl salicylate	Roots and other underground parts	Solvent extraction	—	—	Resolve DOI
Pyrrolidone	Roots and other underground parts	Solvent extraction	—	—	Resolve DOI
Scopoletin	Bark	Solvent extraction	—	—	Resolve DOI
Scopoletin	Roots and other underground parts	Solvent extraction	—	—	Resolve DOI
Scopoletin	Roots and other underground parts	Solvent extraction	—	Mass Spectroscopy and hyphenated methods without chromatography	Resolve DOI
Scopoletin	Trunk	Solvent extraction	—	—	Resolve DOI
Scopoletin	Leaves	Solvent extraction	—	Nuclear Magnetic Resonance (NMR)	Resolve DOI
Scopoletin	Roots and other underground parts	Solvent extraction	—	—	Resolve DOI
2-ethylfuran	Aerial part of plants	Solvent extraction	0.05 Percent	GC-FID	No resolvable identifier
Benzaldehyde	Aerial part of plants	Solvent extraction	0.05 Percent	GC-FID	No resolvable identifier
Ethyl salicylate	Aerial part of plants	Solvent extraction	0.09 Percent	GC-FID	No resolvable identifier
Hex-3-enyl salicylate	Aerial part of plants	Solvent extraction	0.26 Percent	GC-FID	No resolvable identifier
Isobutyl salicylate	Aerial part of plants	Solvent extraction	0.07 Percent	GC-FID	No resolvable identifier
Methyl salicylate	Aerial part of plants	Solvent extraction	61.49 Percent	GC-FID	No resolvable identifier
P-tolualdehyde	Aerial part of plants	Solvent extraction	0.05 Percent	GC-FID	No resolvable identifier
Pentyl salicylate	Aerial part of plants	Solvent extraction	0.07 Percent	GC-FID	No resolvable identifier
Scopoletin	Seed	Solvent extraction	—	—	No resolvable identifier

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Neurotoxicity	Neurologic	Aerial part of plants	Solvent extraction	Human (as organism)	Case report	Resolve DOI

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Jauregui, X., Clavo, Z.M., Jovel, E.M., Pardo-De-Santayana, M. Plantas con madre: Plants that teach and guide in the shamanic initiation process in the East-Central Peruvian Amazon. Journal of Ethnopharmacology, 2011, vol. 134, no. 3, p. 739-752. DOI
Sanz-Biset, Jaume., Canigueral, Salvador. Plant use in the medicinal practices known as strict diets in Chazuta valley (Peruvian Amazon). JOURNAL OF ETHNOPHARMACOLOGY, 2011, vol. 137, no. 1, p. 271-288. DOI
LLOYD, HA., FALES, HM., GOLDMAN, ME., JERINA, DM., PLOWMAN, T., SCHULTES, RE. BRUNFELSAMIDINE - A NOVEL CONVULSANT FROM THE MEDICINAL PLANT BRUNFELSIA-GRANDIFLORA. TETRAHEDRON LETTERS, 1985, vol. 26, no. 22, p. 2623-2624. DOI
Castioni, P., Kapetanidis, I. Volatile constituents from Brunfelsia grandiflora ssp. grandiflora: Qualitative analysis by GC-MS. Scientia Pharmaceutica, 1996, vol. 64, no. 1, p. 83-91.
de Campos, Sonia Machado. Scopoletin in Brunfelsia seeds. Anais. Acad. Brasil Cienc., 1964, p. 511-513.
Fuchino, Hiroyuki., Sekita, Setsuko., Mori, Kanami., Kawahara, Nobuo., Satake, Motoyoshi., Kiuchi, Fumiyuki. A new leishmanicidal saponin from Brunfelsia grandiflora. CHEMICAL & PHARMACEUTICAL BULLETIN, 2008, vol. 56, no. 1, p. 93-96. DOI
BENNETT, BC. HALLUCINOGENIC PLANTS OF THE SHUAR AND RELATED INDIGENOUS GROUPS IN AMAZONIAN ECUADOR AND PERU. BRITTONIA, 1992, vol. 44, no. 4, p. 483-493. DOI

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature