Botanical species · safety record

Bryonia dioica

The EFSA Compendium of Botanicals holds 2 constituent measurements and 2 adverse-effect records for Bryonia dioica. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Bryonia dioica Jacq.

2Constituent measurements

2Safety records

3Cited sources

6Licensed products (Canada)

Also recorded as

Bryonia cretica L. subsp. dioica (Jacq.) Tutin

Synonyms are carried from the source compendium. A species may be traded and studied under more than one name, which is exactly how a safety record gets lost.

Regulatory presence

Health Canada's Licensed Natural Health Products Database holds 6 licensed products naming Bryonia dioica as a medicinal ingredient, matched on the exact Latin binomial. A licence records that a product met the regulator's requirements for sale in Canada. It is not evidence that the product works.

Source material stated

Fresh root harvested before the plant comes into flower
Root
Subterranean parts

What the records describe

Constituents measured

Plant parts

Preparations

Effect types

Target tissues

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

Substance	Plant part	Preparation	Concentration	Analytical method	Source
Cucurbitacins	Unspecified	Solvent extraction	—	Standard Chromatographic tests (paper- thin layer- and column chromatography)	Resolve DOI
Lectins	Unspecified	Solvent extraction	—	Unspecified	Resolve DOI

Recorded adverse effects

Adverse effects reported in the source literature, most often in animal or laboratory models at a stated preparation and dose.

Effect	Target tissue	Plant part	Preparation	Test organism	Test type	Source
Digestive	Digestive	Fruit unspecified	—	Human (as organism)	Acute toxicity	No resolvable identifier
Digestive	Digestive	Fruit unspecified	—	Human (as organism)	Acute toxicity	No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

Battelli, MG., Barbieri, L., Bolognesi, A., Buonamici, L., Valbonesi, P., Polito, L., VanDamme, EJM., Peumans, WJ., Stirpe, F. Ribosome-inactivating lectins with polynucleotide: Adenosine glycosidase activity. FEBS LETTERS, 1997, vol. 408, no. 3, p. 355-359. DOI
Yamani, Amal., Bunel, Valerian., Antoine, Marie-Helene., Husson, Cecile., Stevigny, Caroline., Duez, Pierre., Elachouri, Mostafa., Nortier, Joelle. Substitution between Aristolochia and Bryonia genus in North-Eastern Morocco: Toxicological implications. JOURNAL OF ETHNOPHARMACOLOGY, 2015, vol. 166, p. 250-260. DOI
Veit, M., Martin, E. Major poisonous plants: Components and their pharmacology. Pharmazeutische Zeitung, 1998, vol. 143, no. 26, p. 11-15.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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Independent literature