Botanical species · safety record

Bupleurum rotundifolium

The EFSA Compendium of Botanicals holds 8 constituent measurements for Bupleurum rotundifolium. This page reports what those source records contain and how to reach them. It carries no effect estimate, no dose and no recommendation.

Accepted name in source: Bupleurum rotundifolium L.

8Constituent measurements
0Safety records
6Cited sources
0Licensed products (Canada)

Regulatory presence

No Health Canada licensed natural health product in the snapshot names this species as a medicinal ingredient under this exact binomial. Absence here means absence from this one register under this one name, not absence from trade, and not a safety verdict.

What the records describe

Constituents measured

  • Pentacyclic triterpene saponins4
  • 1,8-cineole1
  • 2-pentylfuran1
  • Myrcene1
  • Polyacetylene derivatives1

Plant parts

  • Fruit unspecified5
  • Leaves2
  • Aerial part of plants1

Preparations

  • Solvent extraction5
  • Essential oil3

Recorded constituents

What analytical work has found in this species, at which plant part and preparation. A measured constituent is a fact about material, not about effect.

SubstancePlant partPreparationConcentrationAnalytical methodSource
1,8-cineoleFruit unspecifiedEssential oil2.2 PercentGC-MSNo resolvable identifier
2-pentylfuranFruit unspecifiedEssential oil1.5 PercentGC-MSNo resolvable identifier
MyrceneFruit unspecifiedEssential oil1.9 PercentGC-MSNo resolvable identifier
Pentacyclic triterpene saponinsAerial part of plantsSolvent extractionNuclear Magnetic Resonance (NMR)No resolvable identifier
Pentacyclic triterpene saponinsLeavesSolvent extractionNuclear Magnetic Resonance (NMR)No resolvable identifier
Pentacyclic triterpene saponinsLeavesSolvent extractionNuclear Magnetic Resonance (NMR)No resolvable identifier
Pentacyclic triterpene saponinsFruit unspecifiedSolvent extractionNuclear Magnetic Resonance (NMR)No resolvable identifier
Polyacetylene derivativesFruit unspecifiedSolvent extractionEnzyme-linked immunosorbent assay (ELISA)No resolvable identifier

Cited sources

The literature the compendium cites for this species. Metatron Health has no relationship with these authors or journals and earns nothing from citing them.

  1. Akin, Mehtap., Saracoglu, Hatice Taner., Demirci, Betul., Baser, Kemal Husnu Can., Kucukoduk, Mustafa. Chemical Composition and Antibacterial Activity of Essential Oils from Different Parts of Bupleurum rotundifolium L.. RECORDS OF NATURAL PRODUCTS, 2012, vol. 6, no. 3, p. 316-320.
  2. Nakano, Y., Matsunaga, H., Saita, T., Mori, M., Katano, M., Okabe, H. Antiproliferative constituents in Umbelliferae plants - II. Screening for polyacetylenes in some Umbelliferae plants, and isolation of panaxynol and falcarindiol from the root of Heracleum moellendorffii. BIOLOGICAL & PHARMACEUTICAL BULLETIN, 1998, vol. 21, no. 3, p. 257-261.
  3. Nakahara, Yuko., Okawa, Masafumi., Kinjo, Junei., Nohara, Toshihiro. Oleanene Glycosides of the Aerial Parts and Seeds of Bupleurum falcatum and the Aerial Parts of Bupleurum rotundifolium, and Their Evaluation as Anti-hepatitis Agents. CHEMICAL & PHARMACEUTICAL BULLETIN, 2011, vol. 59, no. 11, p. 1329-1339.
  4. AKAI, E., TAKEDA, T., KOBAYASHI, Y., CHEN, Y., OGIHARA, Y. MINOR TRITERPENOID SAPONINS FROM THE LEAVES OF BUPLEURUM-ROTUNDIFOLIUM L. CHEMICAL & PHARMACEUTICAL BULLETIN, 1985, vol. 33, no. 11, p. 4685-4690.
  5. AKAI, E., TAKEDA, T., KOBAYASHI, Y., OGIHARA, Y. SULFATED TRITERPENOID SAPONINS FROM THE LEAVES OF BUPLEURUM-ROTUNDIFOLIUM-L. CHEMICAL & PHARMACEUTICAL BULLETIN, 1985, vol. 33, no. 9, p. 3715-3723.
  6. Fujioka, T., Yoshida, K., Fujii, H., Nagao, T., Okabe, H., Mihashi, K. Antiproliferative constituents from umbelliferae plants VI. New ursane-type saikosaponin analogs from the fruits of Bupleurum rotundifolium. CHEMICAL & PHARMACEUTICAL BULLETIN, 2003, vol. 51, no. 4, p. 365-372.

Boundary

A constituent measurement is a fact about material at a stated preparation, not a statement about what that material does in a person. An adverse-effect or genotoxicity record is an observation reported in a source, most often in an animal or laboratory model. Neither is a Metatron Health conclusion about causality, human risk or benefit, and the absence of a record is not proof that a preparation is safe. Nothing here is diagnosis, prescribing or individual medical care.

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